1.
ACS Med Chem Lett
; 9(1): 61-64, 2018 Jan 11.
Artículo
en Inglés
| MEDLINE
| ID: mdl-29348813
RESUMEN
We report the first synthesis of the plant isoflavonoid biliatresone. The convergent synthesis has been applied to the synthesis of several analogs, which have facilitated the first structure-activity relationship study for this environmental toxin that, on ingestion, recapitulates the phenotype of biliary atresia.