RESUMEN
From propolis samples from Kenya, two new arylnaphtalene lignans were isolated, tetrahydrojusticidin B 1 and 6-methoxydiphyllin 2, along with four known phenolic compounds 5-8, found for the first time in propolis. The structures of the compounds were elucidated based on their spectral properties. The geranylstilbenes 7 and 8 demonstrated antibacterial activity against S. aureus, and the geranylflavon macarangin 6 possessed antiradical activity against DPPH radicals.
Asunto(s)
Antibacterianos/aislamiento & purificación , Depuradores de Radicales Libres/aislamiento & purificación , Lignanos/aislamiento & purificación , Própolis/química , Kenia , Pruebas de Sensibilidad Microbiana , Estructura Molecular , Naftalenos/aislamiento & purificaciónRESUMEN
Two new polyisoprenylated benzophenones, 18-ethyloxy-17-hydroxy-17,18-dihydroscrobiculatone A and 18-ethyloxy-17-hydroxy-17,18-dihydroscrobiculatone B, together with the known scrobiculatones A and B, were isolated from Venezuelan propolis. The scrobiculatones A and B showed significant antibacterial activity and moderate toxicity to Artemia salina nauplii.