RESUMEN
Progress in gene-drive research has stimulated discussion and debate on ethical issues including community engagement and consent, policy and governance, and decision-making involved in development and deployment. Many organizations, academic institutions, foundations, and individual professionals have contributed to ensuring that these issues are considered prior to the application of gene-drive technology. Central topics include co-development of the technology with local stakeholders and communities and reducing asymmetry between developers and end-users. Important questions include with whom to conduct engagement and how to define community acceptance, develop capacity-building activities, and regulate this technology. Experts, academics, and funders have suggested that global frameworks, standards, and guidelines be developed to direct research in answering these important questions. Additionally, it has been suggested that ethical principles or commitments be established to further guide research practices. The challenging and interesting contradiction that we explore here is that the vast majority of these conversations transpire with little or no input from potential end-users or stakeholders who, we contend, should ultimately determine the fate of the technology in their communities. The question arises, whose concerns regarding marginalization, disempowerment, and inequity should be included in discussions and decisions concerning how inequities are perceived and how they may be addressed? At what stage will true co-development occur and how will opinions, perspectives and knowledge held by low-income country stakeholders be applied in determining answers to the questions regarding the ethics being debated on the academic stage? Our opinion is that the time is now.
RESUMEN
Tropidurus oreadicus Rodrigues 1987 is a recently described species, thus there are no reports of helminthes parasites for this species. In this study, a morphological characterisation was performed of a nematode species parasite of the large intestine of T. oreadicus captured in an urban area. This urban area is similar to the estuarine dale from Guamá river and the "igarapés" of Belém, Pará State, Brazil. Morphological analysis suggested that the parasite is a new species of nematode, based mainly on the number and distribution pattern of the caudal papillae in males, which is unique for this species. In the present work, we describe for the first time the structure, number, and disposition of the cervical papillae. The morphological data were supported by scanning electron microscopy, which served as an important tool for distinguishing these nematodes from other species of the genus.
