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1.
Pan Afr Med J ; 48: 56, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-39315063

RESUMEN

Liposarcoma is a rare primitive mesenchymal tumor, developed at the expense of adipose tissue and with a preferential location in the thigh. We report an observation of liposarcoma in the buttock. A 56-year-old man, presented with a tumor of the right buttock for 2 years. Examination revealed an inflammatory, ulcerated tumor in the upper-external quadrant of the right buttock, measuring about 8 cm. Bilateral inguinal adenopathies were associated. The diagnostic hypotheses were: a squamous cell carcinoma, a cutaneous lymphoma, and cutaneous metastases. An anatomical examination confirmed the diagnosis of myxoid round-cell liposarcoma. The extension work-up appeared compatible with secondary pleuropulmonary, hepatic, cutaneous, and lymph node neoplastic localizations. The patient was treated with chemotherapy with the Adriamycin-carboplatin protocol. The evolution was rapidly fatal after a few weeks after the first course of chemotherapy. It should be evoked in front of any ulcerated tumor of the buttock.


Asunto(s)
Liposarcoma Mixoide , Neoplasias Cutáneas , Humanos , Nalgas/patología , Persona de Mediana Edad , Masculino , Liposarcoma Mixoide/patología , Liposarcoma Mixoide/diagnóstico , Liposarcoma Mixoide/tratamiento farmacológico , Neoplasias Cutáneas/patología , Neoplasias Cutáneas/diagnóstico , Resultado Fatal , Protocolos de Quimioterapia Combinada Antineoplásica/administración & dosificación , Doxorrubicina/administración & dosificación
2.
PLoS Negl Trop Dis ; 17(11): e0011372, 2023 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-37956163

RESUMEN

Mycetomas are endemic diseases in tropical and sub-tropical countries of Africa, Asia and America, mainly affecting rural populations living below the poverty line. We report a particular case of a mycetoma associated with pregnancy whose evolution was good, but at the cost of significant financial expenses. This was a 39-year-old woman who developed a fungal mycetoma due to Madurella mycetomatis from the ingunocrural region. The patient had to develop several previous pregnancies on this site of mycetoma, the outcome of which was favorable. The last pregnancy was accompanied by an aggravation of the mycetoma in the form of polyfistulized inflammatory swelling of the right inguino-crural region emitting black grains. Magnetic Resonance Imaging (MRI) of the region showed invasion of the adductor muscles at the level of the root of the thigh on its antero-internal side with no sign of pelvic extension or underlying bone lesion. The patient was treated by surgery associated with antifungal treatment. The evolution was favorable for pregnancy and mycetoma.


Asunto(s)
Madurella , Micetoma , Femenino , Humanos , Embarazo , Adulto , Micetoma/diagnóstico , Micetoma/tratamiento farmacológico , Micetoma/cirugía , Antifúngicos/uso terapéutico , África , Asia
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