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OBJECTIVE: This study aimed to present 2 cases with unusual lead complications in InterStim devices implanted in patients with refractory overactive bladder symptoms. MATERIALS: Two patients with InterStim implants presented with loss of efficacy. Both patients required lead revision surgery with findings of a twisted lead with associated lead migration. RESULTS: In both cases, revision surgery revealed twisting of the InterStim lead causing retrograde lead displacement. Patients were managed with lead removal and placement of a new lead. At the time of revision, one patient had a seroma within a large pocket of the implantable pulse generator (IPG) site, which was managed with closure and development of a new IPG pocket. In both cases, revision with new lead placement resulted in significant symptom improvement. CONCLUSIONS: Sacral neuromodulation lead complications are known to be among the most consequential adverse events. We report the first 2 cases, to our knowledge, of patients presenting with an InterStim device that lost efficacy due to lead twisting and subsequent retrograde lead migration, likely due to rotation of the IPG within the gluteal pocket. This finding is easily remedied with IPG pocket revision and lead replacement.
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Electrodos Implantados/efectos adversos , Falla de Equipo , Migración de Cuerpo Extraño/diagnóstico por imagen , Anciano , Terapia por Estimulación Eléctrica/instrumentación , Femenino , Migración de Cuerpo Extraño/cirugía , Humanos , Persona de Mediana Edad , Reoperación , Vejiga Urinaria Hiperactiva/terapiaRESUMEN
OBJECTIVE: To describe a novel surgical option for cystolithiasis management in female patients with no urethral access and prior abdominal surgeries. We present a 51-year-old female with a history of traumatic spinal cord injury with pelvic fractures and resultant neurogenic bladder. She underwent transabdominal bladder neck closure and bladder augmentation with continent diversion 2 years prior. CT abdomen/pelvis demonstrated a 3 cm stone and significant amount of bowel anterior to the bladder. METHODS: Pouchoscopy was performed via ureteroscope through the catheterizable stoma to assess stone location and mobility. A 14F-Foley was inserted for intraoperative decompression. An inverted-U incision was made on the anterior vaginal wall overlying the bladder base. Sharp and blunt dissection was performed in an avascular plane to dissect the vagina off of the bladder. Electrocautery was utilized to open perivesical tissue and the detrusor layer transversely. Further sharp dissection of perivesical tissue was achieved using Metzenbaum scissors. The bladder was filled via stoma Foley to improve visualization of bladder mucosa. Cystotomy was made and the 3 cm stone was removed, intact, using a Babcock. The bladder was closed in 2 layers with absorbable suture in running fashion. The bladder was refilled and the closure was watertight. The outer detrusor layer was closed with running locking 2-0 Polysorb, and a separate layer of perivesical tissue was closed over our 2-layer bladder closure using simple interrupted stitches. The vaginal flap was closed with running-locking 2-0 Polysorb. RESULTS: Operative time was 55 minutes. Estimated blood loss was 25 cc. The patient was discharged on postoperative-day 0 with a 14F-Foley in the catheterizable channel. The Foley was removed at the 3-week postoperative visit and patient resumed self-catheterization. No postoperative imaging was required. No complications were reported within 1 year. CONCLUSION: We demonstrate the feasibility of transvaginal cystolithotomy in females with bowel overlying bladder and no urethral access.
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Cálculos de la Vejiga Urinaria/cirugía , Femenino , Humanos , Persona de Mediana Edad , Procedimientos Quirúrgicos Urológicos/métodos , VaginaRESUMEN
Pelvic organ prolapse is common in parous women, although few report symptoms. The incidence of posterior compartment prolapse, or rectocele, is less well-reported. Posterior vaginal wall prolapse is associated with pain, constipation, and splinting. Surgery is the mainstay of therapy for symptomatic rectoceles. Though several surgical techniques have been described, no clear indications for type of repair have emerged. This article reviews the management strategies and draws conclusions about suture-based and site-specific techniques.
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Procedimientos Quirúrgicos Ginecológicos/métodos , Prolapso de Órgano Pélvico/cirugía , Rectocele/cirugía , Técnicas de Sutura , Vagina/cirugía , Femenino , Humanos , Recurrencia , Factores de RiesgoRESUMEN
OBJECTIVE: To determine if using one 250 mL bottle of intravesical contrast followed by sterile saline alters interpretation of fluoroscopic images during fluoro-urodynamics. MATERIALS AND METHODS: Subjects were randomized to receive 250 mL of intravesical contrast followed by sterile saline until maximal cystometric capacity vs non-dilute intravesical contrast alone during fluoro-urodynamics. Interpreters, blinded to study group, graded images on an ordinal rank scale rating confidence in image interpretation. Primary endpoint was differences in image interpretation between the two groups using visual grading characteristics curves and contrast-to-noise ratios (CNR). Secondary endpoints were obtaining anthropometric data such as body mass index and waist circumference to determine predictors of CNR in a multivariate multiple regression analysis. RESULTS: 26 subjects were randomized to receive dilute intravesical contrast and 22 non-dilute contrast; two subjects were unable to complete the study. There was no difference in baseline characteristics between the two groups. Visual grading characteristics demonstrated no difference in readability of the fluoroscopic images between groups and CNR was not statistically different between the two groups. No correlation was identified between CNR and waist circumference or body mass index. CONCLUSION: Interpretation of fluoro-urodynamic images and image quality was not altered with using of 250 mL of contrast followed by saline. Expert reviewers did not perceive a difference in their confidence to distinguish between the two groups. Fluoro-urodynamics can be reliably performed using only 250 mL of contrast without compromising the ability to read the fluoroscopic images.
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Medios de Contraste/administración & dosificación , Cistografía/métodos , Fluoroscopía/métodos , Administración Intravesical , Adulto , Antropometría , Medios de Contraste/efectos adversos , Cistografía/efectos adversos , Método Doble Ciego , Femenino , Fluoroscopía/efectos adversos , Humanos , Masculino , Persona de Mediana Edad , Estudios Prospectivos , Solución Salina/administración & dosificación , Relación Señal-Ruido , Uretra/diagnóstico por imagen , Vejiga Urinaria/diagnóstico por imagen , UrodinámicaRESUMEN
INTRODUCTION: Robotic surgical procedures have become more common in female pelvic reconstruction. Purported benefits of robotic assisted pelvic floor reconstruction (RAPFR) procedures include shorter hospital stay, faster recovery, lower blood loss, and decreased postoperative pain. Following RAPFR procedures, the current accepted practice is discharge after a one-night hospitalization. We assessed whether same day discharge (SDD) affects the short term safety of and patient satisfaction with robotic assisted pelvic floor reconstructive procedures, relative to those who remain hospitalized overnight. MATERIALS AND METHODS: We retrospectively reviewed the charts of women who underwent RAPFR procedures between October 2015 and October 2016. A same day discharge protocol for RAPFR was initiated in July 2016. To date, 10 patients have undergone SDD. These patients were compared to the consecutive patients from the prior 9 months who stayed overnight. To evaluate short term safety, we reviewed the medical record for any unscheduled Cleveland Clinic emergency department (ED) and/or office visits within 30 days of the RAPFR procedure. We then sent a mailed survey to all patients, querying their pelvic organ prolapse-related PGI-I and also offering a postoperative satisfaction questionnaire. Demographic, perioperative, postoperative data and survey results were compared using Student's t test and Fisher's exact test. RESULTS: In our series, 38 patients (95%) underwent robotic assisted sacrocolpopexy (RASC). Only 2 (5%) had a different RAPFR procedure, a robotic assisted vaginal mesh excision. Concomitant robotic assisted supracervical hysterectomy (SCH) was performed in 9 patients (30%) in the overnight group, whereas 1 of the SDD patients underwent SCH (10%). Demographics and operative characteristics did not differ between groups. Ultimately, patients in the SDD group were no more likely than the overnight group to require an unscheduled ED or office visit in the early postoperative period. With respect to satisfaction, no significant differences were observed between groups, with both groups noting substantial improvement in POP symptoms following surgery. CONCLUSIONS: In this pilot study, same day discharge after RAPFR procedures appears to be safe and feasible. RAPFR procedures were well-tolerated, with no difference in ED or non-urology office visits occurring during the early post-operative period in our series, regardless of length of stay. Patient satisfaction was equivalent between groups and universally high.
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Procedimientos Quirúrgicos Ambulatorios/métodos , Alta del Paciente , Prolapso de Órgano Pélvico/cirugía , Procedimientos de Cirugía Plástica/métodos , Procedimientos Quirúrgicos Robotizados/métodos , Anciano , Pérdida de Sangre Quirúrgica , Estudios de Cohortes , Bases de Datos Factuales , Estudios de Factibilidad , Femenino , Estudios de Seguimiento , Humanos , Tiempo de Internación , Persona de Mediana Edad , Tempo Operativo , Dolor Postoperatorio/fisiopatología , Dolor Postoperatorio/terapia , Seguridad del Paciente , Prolapso de Órgano Pélvico/diagnóstico , Procedimientos de Cirugía Plástica/efectos adversos , Estudios Retrospectivos , Procedimientos Quirúrgicos Robotizados/efectos adversos , Índice de Severidad de la Enfermedad , Factores de Tiempo , Resultado del TratamientoRESUMEN
PURPOSE: We sought to determine the safety of sacral neuromodulation in patients during lumbosacral 1.5 Tesla magnetic resonance imaging. MATERIALS AND METHODS: We prospectively recruited patients with a sacral neuromodulation implant who required lumbosacral 1.5 Tesla magnetic resonance imaging. Before imaging the patients completed validated urinary symptom questionnaires and a survey regarding the usual sacral neuromodulation sensation. The implantable pulse generator was interrogated, and impedances, battery life and stimulus amplitude sensory thresholds were assessed before and after magnetic resonance imaging. Devices were switched off before the patient entered the scanner. Patients were monitored during the study and magnetic resonance imaging related adverse events questionnaires were completed after imaging. Validated questionnaires were repeated 1 month after magnetic resonance imaging to assess for changes in sacral neuromodulation therapeutic efficacy. RESULTS: A total of 11 patients were enrolled in the study. Lower back pain, which was noted by 6 of the 11 patients (55%), was the most common indication for imaging. Immediately after magnetic resonance imaging only 1 patient reported mild discomfort during imaging at the site of the implantable pulse generator. This discomfort was present only during the scan and not afterward. Two patients reported warmth at the implantable pulse generator site during the scan, which was also present only during scanning. Patients did not report any other adverse events. There were no major changes in impedance or battery life after magnetic resonance imaging. Stimulus amplitude sensory thresholds and stimulation localization were unchanged. Validated questionnaires 1 month after imaging did not show worsening scores compared to scores before imaging. CONCLUSIONS: No significant adverse events occurred in patients implanted with a Medtronic InterStim™ II device who underwent a 1.5 Tesla lumbosacral magnetic resonance imaging scan. Therapeutic efficacy of sacral neuromodulation was unchanged 1 month after imaging.
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Neuroestimuladores Implantables , Plexo Lumbosacro/diagnóstico por imagen , Imagen por Resonancia Magnética/efectos adversos , Anciano , Anciano de 80 o más Años , Femenino , Humanos , Masculino , Persona de Mediana Edad , Seguridad del Paciente , Proyectos Piloto , Estudios ProspectivosRESUMEN
PURPOSE OF REVIEW: Overactive bladder (OAB) affects millions of people in the USA and has a significant impact on their quality of life. Despite having a number of safe and effective ways of managing refractory OAB patients, there are many promising new technologies actively being studied and developed for the treatment of this population. This review examines current new devices and technologies under study for the treatment of OAB. RECENT FINDINGS: Modifications to already established therapies such as sacral nerve stimulation (SNS) or tibial nerve stimulation (TNS) are currently being studied for refractory OAB. On the SNS front, a newly rechargeable, smaller neurostimulator has been developed and has shown promising results for the treatment of refractory OAB. There are two newly implantable TNS devices actively being studied for the treatment of refractory OAB. These implanted TNS systems will allow the patient to receive treatment from the comfort of their home without the need for frequent office visits. Most recently, radiofrequency ablation intravesical therapy has been proposed as a newer technology with the potential to reduce OAB symptoms. There are many new technologies actively being studied and developed for the management of refractory OAB patients. If shown to be safe and efficacious, these therapies may one day alter our current management of patients with OAB.
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Terapia por Estimulación Eléctrica/métodos , Vejiga Urinaria Hiperactiva/terapia , Difusión de Innovaciones , Humanos , Tratamiento de Radiofrecuencia Pulsada , Estimulación Eléctrica Transcutánea del NervioRESUMEN
Patients with pelvic organ prolapse (POP) may present with a large combination of symptoms including overactive bladder (OAB) symptoms such as urgency, frequency, and urgency incontinence. The explanation as to why these symptoms are more prevalent in POP patients is not clearly understood, but there seems to be an overall agreement that prolapse-induced bladder outlet obstruction (BOO) may trigger bladder changes resulting in OAB symptoms. Presuming this to be true, many of the studies managing OAB in POP patients have focused on the surgical management of prolapse and its aftermath, which in many of the patients leads to improvement of OAB symptoms. This review presents the most recent studies and evidence looking at management of OAB in the face of POP and seeks to evaluate if there is any association between prolapse severity and OAB symptoms.
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Prolapso de Órgano Pélvico/terapia , Vejiga Urinaria Hiperactiva/terapia , Humanos , Prolapso de Órgano Pélvico/etiología , Prevalencia , Obstrucción del Cuello de la Vejiga Urinaria/etiología , Vejiga Urinaria Hiperactiva/complicaciones , Vejiga Urinaria Hiperactiva/epidemiología , Vejiga Urinaria Hiperactiva/patología , Incontinencia UrinariaRESUMEN
Penetrating injuries are a major cause of mortality and morbidity. The most common diagnostic tool used in this setting is CT scan. We present a case of a traumatic hepatopleural fistula demonstrated by hepatobiliary scintigraphy. Traumatic abdominal injuries to the liver and diaphragm can result in complications, whose detection by CT scan is not always straightforward. Hepatobiliary scintigraphy is very useful in the search of bilious pleural effusions.
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Fístula del Sistema Digestivo/diagnóstico por imagen , Hepatopatías/diagnóstico por imagen , Enfermedades Pleurales/diagnóstico por imagen , Fístula del Sistema Respiratorio/diagnóstico por imagen , Fístula del Sistema Digestivo/etiología , Humanos , Hepatopatías/etiología , Masculino , Enfermedades Pleurales/etiología , Cintigrafía , Fístula del Sistema Respiratorio/etiología , Heridas Penetrantes/complicacionesRESUMEN
OBJECTIVE: The prevalence of human papillomavirus (HPV) in the oral cavity has not been as well studied as genital infection and its prevalence among drug users is uncertain. This study describes the prevalence and correlates of oral HPV infection among a sample of drug users in Puerto Rico (PR). METHODS: Cross-sectional study of 271 drug users aged 18-35 years, not undergoing substance abuse treatment, living in the San Juan metropolitan area. Oral samples were collected through an oral rinse and HPV infection status was detected through PCR and HPV typing. Information on covariates was obtained through face-to-face interviews and serum analyses. RESULTS: A total of 34 participants were positive for any HPV type (12.5%), whereas 13 individuals (4.8%) were positive for one of the 38 type-specific HPV probes evaluated. Among those HPV positive, the most common HPV type detected was non-oncogenic HPV 72 (11.8%, n = 4). Oncogenic HPV types detected were 35 (5.9%) and 56 (2.9%). Factors associated with oral HPV infection included binge drinking (OR = 3.85, 95% CI = 1.40, 10.58), HIV positivity (OR = 4.67, 95% CI = 1.58, 13.74) and ever having engaged in commercial sex (OR = 3.55, 95% CI = 1.46, 8.67); infection did not differ by age or gender. CONCLUSION: Consistent with previous studies in the genital and oral tract, HIV infection, alcohol abuse and commercial sex practices were strongly associated with oral HPV infection. Future studies should assess the implications of oral HPV infection on oral cancer risk in this population.
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Alphapapillomavirus/aislamiento & purificación , Boca/virología , Infecciones por Papillomavirus/epidemiología , Estomatitis/epidemiología , Trastornos Relacionados con Sustancias/epidemiología , Adolescente , Adulto , Alcoholismo/epidemiología , Comorbilidad , Estudios Transversales , ADN Viral/análisis , Femenino , Seropositividad para VIH/epidemiología , Pruebas de ADN del Papillomavirus Humano , Humanos , Masculino , Infecciones por Papillomavirus/virología , Prisioneros , Puerto Rico/epidemiología , Factores de Riesgo , Muestreo , Trabajo Sexual , Conducta Sexual , Factores Socioeconómicos , Estomatitis/virología , Estrés Psicológico/epidemiología , Adulto JovenRESUMEN
This study was aimed at examining the relationship between suicidal attempts, polydrug use, and depression in adolescents. A sample of 691 adolescents and their parents were interviewed. Subjects who met the criteria for depression and those who used alcohol were significantly more likely to be suicidal attempters (OR = 6.8, p < 0.001; OR = 7.5, p < 0.001). Polydrug users were significantly more likely to attempt suicide (OR = 8.8, p = 0.032). Adolescents with mothers who met the criteria for depression were more likely to report suicide attempts (OR = 2.4, p = 0.069). Health professionals need to screen for polydrug use and depression to prevent future suicidal behaviors.
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Alcoholismo/complicaciones , Depresión/complicaciones , Trastornos Relacionados con Sustancias/complicaciones , Intento de Suicidio/estadística & datos numéricos , Adolescente , Consumo de Bebidas Alcohólicas/efectos adversos , Alcoholismo/epidemiología , Alcoholismo/psicología , Niño , Depresión/epidemiología , Depresión/psicología , Femenino , Estudios de Seguimiento , Humanos , Incidencia , Entrevistas como Asunto , Masculino , Padres/psicología , Prevalencia , Puerto Rico/epidemiología , Factores de Riesgo , Medio Social , Factores Socioeconómicos , Trastornos Relacionados con Sustancias/epidemiología , Trastornos Relacionados con Sustancias/psicología , Intento de Suicidio/psicologíaRESUMEN
OBJECTIVE: This research aims to understand the circumstances associated with school dropout in a cohort of Puerto Rican adolescents. METHODS: The study collected data from adolescents and their parents. Information related to school dropout among adolescents was obtained from the second year follow-up data from the longitudinal study funded by NIDA "Risky Families Embedded in Risky Environments" (Grant No. R01 DA 15301). Data was collected employing a self-administered and a face-to-face interview protocol. Prediction of school dropout was assessed throughout adolescent characteristics, family background, school experiences and behaviors. RESULTS: During the second follow-up, two years after the baseline assessment, approximately 6.2% of the adolescents reported dropping out from school. Logistic regression analysis indicates that older adolescents (OR = 6.6, 1.37-31.67), whose mother used drugs during pregnancy (OR = 4.9, 1.31-17.91), who reported high rates of absenteeism (OR = 4.8, 1.63-14.13), high school grade retention (OR = 3.7, 1.14-12.05), and attended school where teachers were attacked or wounded by students (O R =7.0, 1.44-34.17) were more likely to dropout of school. DISCUSSION: : These findings emphasize the need to further understand the effects of different elements of adolescents' environment such as family and school. It has been posited that dropping out of school is a process whose characteristics can be detected long before it occurs. The fact that students who dropout are more likely to report skip classes and grade retention can be relevant elements in prevention and early intervention for teachers and other school personnel.
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Abandono Escolar/estadística & datos numéricos , Adolescente , Femenino , Predicción , Humanos , Masculino , Puerto RicoRESUMEN
Injection drug users (IDUs) contaminate preparation materials with blood-borne pathogens by using syringes as measuring and dispensing devices. In collaboration with IDUs, we developed a preventive intervention consisting of four new preparation practices aimed at avoiding the use of syringes in the preparation, and reducing the contamination of the materials. This report describes the results of a pilot trial introducing the new practices to ascertain their adoption potential and their potential efficacy in reducing contamination. Participants comprised 37 active IDUs among whom the new practices were promoted during 16 weeks. In addition to self-reported behaviors, the study collected cookers and plastic caps from shooting galleries and tested them for the presence of blood residues. Adoption rates were: (1) cleaning of skin area with hand sanitizer--65.6%; (2) directly pouring water with a dropper into the cooker--56.3%; (3) drawing drug solution with a preparation syringe and syringe filter--34.4%; and, (4) backload rinsing syringes--53.1%. Rates of blood residues detected in cookers and plastic caps were 41.7% prior to the trial, 28.6% at week 8, 24.6% at week 14, and 12.0% at week 18. We believe the results of the pilot trial are compelling and suggest that this intervention merits further formal testing.
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Composición de Medicamentos/métodos , Consumidores de Drogas/educación , Equipo Reutilizado , Conocimientos, Actitudes y Práctica en Salud , Abuso de Sustancias por Vía Intravenosa , Adulto , Investigación Participativa Basada en la Comunidad , Difusión de Innovaciones , Femenino , Infecciones por VIH/prevención & control , Infecciones por VIH/transmisión , Humanos , Masculino , Persona de Mediana Edad , Evaluación de Resultado en la Atención de Salud , Proyectos Piloto , Evaluación de Programas y Proyectos de Salud , Puerto Rico , Abuso de Sustancias por Vía Intravenosa/epidemiología , Abuso de Sustancias por Vía Intravenosa/prevención & control , Jeringas , Adulto JovenRESUMEN
Injection drug users (IDUs) in San Juan, Puerto Rico are characterized by high rates of daily injecting, injection of shared drugs, re-use of injection syringes, and use of shooting galleries. They lack adequate access to new injection syringes and drug preparation equipment, and experience elevated rates of HIV and HCV infection. Between April and August, 2006, researchers and active IDUs collaborated in the development of an experimental HIV/HCV intervention aimed at identifying drug preparation items and practices that will enable IDUs to make drug solutions without potentially contaminated injection syringes contacting materials used to prepare drugs. The collaboration involved discussing and testing a variety of drug preparation items and practices in office and community settings. The process was repeated until concerns that had been raised were resolved, and a tentative set of intervention items and practices to be evaluated in a community field trial was identified. Throughout, a strong emphasis was placed on the capacity of an item or practice to address common problems confronted by IDUs (blunted needles, clogged syringes, injected particles) in addition to the core aim of reducing contamination of preparation materials by blood in injection syringes. This report describes the final selection of items and practices: 1) A small water bottle that permits IDUs to add approximately .05 cc water drops directly to drug powder in cookers; 2) A preparation syringe (a type of ancillary equipment not used for injecting) that permits IDUs to pull up a measurable amount of water to add to drug powder, an alternative to producing water drops; 3) A filtering device, the Sterifilt filter, attached to a preparation syringe, which eliminates the need for cotton or cigarette filters; 4) Use of a preparation syringe to distribute drug solution by backloading to injection syringe(s); 5) A small water bottle enabling IDUs to clean injection syringes by backload rinsing. The overarching aim of this experimental HIV/HCV intervention was to promote the safe re-use of drug preparation and injection items, and to impact the large number of IDUs in San Juan who maintain personal injection syringes, but currently use communal ancillary equipment in shooting galleries and inject drug solutions prepared with other IDUs' injection syringes.
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This study investigates the role of neighborhoods in adolescent violence in poor neighborhoods in San Juan, Puerto Rico. The study is part of a larger longitudinal project examining risk and resilience in adolescents' ages 12 to 15 years old and their caregivers. Using a cross-sectional design, a self-completion questionnaire, and an interviewer questionnaire, the authors assessed violent behaviors among participants across demographics, characteristics, and neighborhood social disorganization using the concepts of physical disorders and social disorder. Adolescent violence was positively associated with social disorder. The finding that adults in these neighborhoods walk around with visible firearms and engage in fighting, may have led adolescents to perceive that violence is an accepted behavior. Furthermore, socially disorganized neighborhoods might be less likely to organize on their own behalf because the occurrence of negative experience limits the amount of social support and resources that are available in the neighborhood.
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Conducta del Adolescente , Delincuencia Juvenil/estadística & datos numéricos , Relaciones Padres-Hijo , Características de la Residencia/estadística & datos numéricos , Medio Social , Población Urbana/estadística & datos numéricos , Adolescente , Conducta del Adolescente/psicología , Estudios Transversales , Femenino , Humanos , Estudios Longitudinales , Masculino , Puerto Rico/epidemiología , Asunción de Riesgos , Factores SocioeconómicosRESUMEN
OBJECTIVE: We analyzed early sexual activity among Hispanic 14 to 15-year-old adolescents residing in a poor neighborhood in Puerto Rico. METHODS: Information from a sample of 325 adolescents was collected from a randomized sample of community households. Logistic regression analysis was used to identify the variables that help explained adolescents' sexual behavior. RESULTS: Adolescents whose parents reported poor communication and poor parent control were more likely to engage in early sexual activity that those peers that did not report this type of family relationship. Adolescents who reported poor parent bonding and lack of discipline were more likely to engage in early sexual relationships. CONCLUSIONS: Intervention and prevention programs need to be aware and address the role of the Hispanic culture in gender differences in early sexual activity in adolescence. If sexual norms related to gender role are changing in Puerto Rico, is a question that needs to be answered in future research.
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Coito , Hispánicos o Latinos , Adolescente , Factores de Edad , Femenino , Humanos , Masculino , Relaciones Padres-Hijo , Puerto RicoRESUMEN
Throughout the world, injection drug users (IDUs) are the group at highest risk for hepatitis C virus (HCV) infection. IDUs residing in the island of Puerto Rico and Puerto Rican IDUs residing in the U.S. mainland have been shown to be at very high risk of infection with HIV. However, the extent to which HCV infection has spread among IDUs in Puerto Rico is not yet known. The aims of this study were to estimate seroprevalence of HCV and to identify the correlates associated with HCV transmission. The sample was drawn through street outreach strategies and was comprised of 400 injection drug users not in treatment, living in the San Juan metropolitan area. HCV and HIV infection were detected by enzyme-linked immunosorbent assay and the results were confirmed by Western blot. Information on sociodemographics, drug use patterns, and risk behaviors was obtained through structured interviews. Bivariate analyses and multivariate logistic regression were used to assess covariates of infection with HCV. The prevalence of HCV infection was 89%. After controlling for sociodemographic characteristics, HCV infection was positively associated with increasing years of injection, injecting in a shooting gallery, tattooing in prison, and self-reported STD infection. Notably, IDUs who had initiated drug injection within the year prior to the study interview had an HCV infection rate of 57%. This study indicates that more aggressive educational programs are urgently needed to reduce the spread of HCV infection among IDUs in Puerto Rico.
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Hepatitis C/epidemiología , Abuso de Sustancias por Vía Intravenosa/epidemiología , Adulto , Western Blotting , Ensayo de Inmunoadsorción Enzimática , Femenino , Infecciones por VIH/epidemiología , Infecciones por VIH/transmisión , Hepatitis C/transmisión , Humanos , Masculino , Puerto Rico/epidemiología , Asunción de Riesgos , Estudios Seroepidemiológicos , Factores SocioeconómicosRESUMEN
El sangrado gastrointestinal de un divertículo de Meckel es una entidad clínica muy difícil de diagnosticar con técnicas endoscópicas o radiografías rutinarias, necesitándose a veces la angiografía. El escintigrama con pertecnetato de tecnecio 99m resulta una alternativa viable para el diagnóstico de esta condición