Comparison Between Traditional and Alternated Resistance Exercises on Blood Pressure, Acute Neuromuscular Responses, and Rating of Perceived Exertion in Recreationally Resistance-Trained Men.

ABSTRACT: Corrêa Neto, VG, Silva, DdN, Palma, A, de Oliveira, F, Vingren, JL, Marchetti, PH, da Silva Novaes, J, and Monteiro, ER. Comparison between traditional and alternated resistance exercises on blood pressure, acute neuromuscular responses, and rating of perceived exertion in recreationally resistance-trained men. J Strength Cond Res 38(5): e211-e218, 2024-The purpose of this study was to compare the acute effects of traditional and alternated resistance exercises on acute neuromuscular responses (maximum repetition performance, fatigue index, and volume load), rating of perceived exertion (RPE), and blood pressure (BP) in resistance-trained men. Fifteen recreationally resistance-trained men (age: 26.40 ± 4.15 years; height: 173 ± 5 cm, and total body mass: 78.12 ± 13.06 kg) were recruited and performed all 3 experimental conditions in a randomized order: (a) control (CON), (b) traditional (TRT), and (c) alternated (ART). Both conditions (TRT and ART) consisted of 5 sets of bilateral bench press, articulated bench press, back squat, and Smith back squat exercises at 80% 1RM until concentric muscular failure. The total number of repetitions performed across sets in the bench press followed a similar pattern for TRT and ART, with significant reductions between sets 3, 4, and 5 compared with set 1 (p < 0.05). There was a significant difference for set 4 between conditions with a lower number of repetitions performed in the TRT. The volume load was significantly higher for ART when compared with TRT. TRT showed significant reductions in BP after 10-, 40-, and 60-minute postexercise and when compared with CON after 40- and 60-minute postexercise. However, the effect size illustrated large reductions in systolic BP during recovery in both methods. Thus, it is concluded that both methods reduced postexercise BP.

Carbon Dots: A Bright Future as Anticounterfeiting Encoding Agents.

Counterfeit products and data vulnerability present significant challenges in contemporary society. Hence, various methods and technologies are explored for anticounterfeiting encoding, with luminescent tracers, particularly luminescent carbon dots (CDs), emerging as a notable solution. CDs offer promising contributions to product security, environmental sustainability, and the circular economy. This critical review aims to highlight the luminescence responsiveness of CDs to physical and chemical stimuli, achieved through nanoengineering their chemical structure. The discussion will delve into the various tunable luminescence mechanisms and decay times of CDs, investigating preferential excitations such as up-conversion, delayed fluorescence, fluorescence, room temperature phosphorescence, persistent luminescence, energy and charge transfer, as well as photo-chemical interactions. These insights are crucial for advancing anticounterfeiting solutions. Following this exploration, a systematic review will focus on the research of luminescent CDs' smart encoding applications, encompassing anticounterfeiting, product tracing, quality certification, and information encryption. Finally, the review will address key challenges in implementing CDs-based technology, providing specific insights into strategies aimed at maximizing their stability and efficacy in anticounterfeiting encoding applications.

A Cardiopulmonary Exercise Testing for Prescribing High-Intensity Interval Training Sessions with Elastic Resistance.

This study aims to analyze the agreement of cardiopulmonary variables between a cardiopulmonary exercise test with elastic resistance (CPxEL) and high-intensity interval exercise with elastic resistance (EL-HIIE). METHODS: Twenty-two physically independent participants were recruited. Visit one consisted of conducting a health survey and anthropometric assessment. On visit two, the participants performed CPxEL. After seven days, on visit three, the participants performed EL-HIIE. The CPxEL was carried out on a rubber mat demarcated by lines representing eight stages. The test consisted of alternating back and forth steps against elastic resistance. The increments were performed at a rate of one stage per minute, following a cadence controlled by a metronome calibrated by beats per minute (bpm). The EL-HIIE was performed at the stage corresponding to an intensity of ~85% VO2max, as determined by CPxEL. The EL-HIIE consisted of 10 × 1 min (work):1 min (passive rest), with a cadence of 200 bpm. Cardiopulmonary parameters, heart rate (HR), and oxygen consumption (VO2) were measured during exercise. Bland-Altman was applied to analyze the agreement between the HR and VO2 found in EL-HIIE and the values prescribed by CPxEL (~85-90% VO2max). RESULTS: The HRpeak and VO2peak in the EL-HIIE showed good agreement with the VO2CPxEL and HRCPxEL values, showing an average difference of (-1.7 mL·kg-1·min-1) and (0.3 bpm). CONCLUSIONS: The results of the present study demonstrate the agreement of cardiopulmonary variables between the CPxEL and the EL-HIIE. Therefore, for a more specific prescription of EL-HIIE intensity, CPxEL can be used.

Power and anaerobic capacity in female soccer: A comparison between different age-categories

Introduction: Nowadays, female soccer can be considered one of fastest growing sports trends. However, investigations regarding female soccer players’ performance are still scarce comparing to male soccer players. The purpose of this study was to compare the athletic profile of female soccer players from adult and youth categories of a professional soccer club. Material and methods Forty-two female soccer players from a professional soccer club were recruited for this investigation (adult category n = 21; youth category n = 21). Performance tests were randomly assigned. Aerobic capacity, sprint, change-of-direction ability, and power performance were assessed. Results There were no significant differences between groups for any of the proposed parameters. Also, better unilateral jump performance for the right leg was observed among adult players (p = 0.05). Conclusions The study suggests that there is no clear discrepancy between youth and adult categories regarding power, sprint, change-of-direction ability, and aerobic performance. However, a trend towards lower limb asymmetry was observed among adult players. (AU)

Controlling Morphing Behavior in 4D Printing: A Review About Microstructure and Macrostructure Changes in Polylactic Acid.

Four-dimensional (4D) printing combines stimulus-responsive materials with additive manufacturing (AM) technologies. This new concept of printing three-dimensional (3D) objects opens the possibility for solving processing issues, through the production of complex geometries that can undergo programmed temporal changes in response to external stimuli. However, as 4D technology emerges from AM, various challenges still need to be explored, such as the controlled morphing effect. Understanding the aspects related to this behavior, both at the macroscopic level of the structure and at the microscopic level of the polymeric chain, is fundamental. Focused on thermoplastic poly(lactic acid) (PLA) printed by fused deposition modeling, this review addressed the influence of molecular weight, polymeric chain modifications, and 3D printing parameters on the shape change effect of a PLA-based material. The glass transition temperature proved to be a highly important parameter, which can be modified by molecular weight changes. Nozzle temperature, fill density, print patterns, and raster angle are 3D printing parameters that influence the material shape change. Shape recovery is highly dependent on the recovery temperature. Potential applications for shape memory structures are also addressed in this review.

Efficacy of photobiomodulation in the treatment of oral mucositis in patients undergoing antineoplastic therapy: systematic review and meta-analysis.

PURPOSE: To evaluate the effectiveness of photobiomodulation in the treatment of oral mucositis. METHODS: Systematic review and meta-analysis encompassing in the electronic databases: LILACS, MEDLINE, EMBASE, COCHRANE, SCOPUS, WEB OF SCIENCE, and CINAHL and in http://clinicaltrials.gov . Eligibility criteria were randomized, non-randomized, and observational studies that used photobiomodulation for the treatment of oral mucositis. The endpoints were reduction in the severity of oral mucositis, duration of lesions, and pain reduction. For data analysis, the Review Manager 5.4 program was used. RESULTS: A total of 316 studies were identified, 297 in the electronic databases and 19 in http://clinicaltrials.gov . After removing duplicates, 260 studies were selected for title and abstract reading, of which 223 were excluded. A total of 37 studies were chosen for full reading, of which 6 were included in the review, totaling 299 patients. The treatment used was photobiomodulation. The patients were divided into two groups: the laser group used only photobiomodulation or associated with other therapies, and the control group did not use photobiomodulation. For the endpoint reduction in the severity of oral mucositis (OM), the chance of reduction of the OM was greater in the laser group as compared to the control group. For the endpoints duration of OM lesions and pain reduction, it was not possible to carry out a meta-analysis due to the high heterogeneity between studies. In the interpretation of the meta-analysis, the reduction in the severity of oral mucositis was greater in the group that received photobiomodulation. CONCLUSION: Photobiomodulation was effective in the treatment of oral mucositis.

Musculoskeletal Injury Prevalence, Pain Perception, and Physical Activity Level Among Brazilian Strength and Cross-Training Practitioners.

In this study, we sought to determine the prevalence of musculoskeletal injuries, perceived pain, and physical activity level among Brazilian practitioners of strength training (ST) and functional fitness (FF). Participants were 311 men and women who trained in 10 FF training centers and seven ST gyms. Each participant completed surveys of the prevalence of musculoskeletal injuries, their pain perception, and their physical activity level. A chi square test was used to analyze associations between groups and distributions of injuries. When any significant difference was observed, the difference score was analyzed through the adjusted residual values. Fisher's exact test was used to determined the associations between musculoskeletal injury prevalence and training modality (FF and ST) and between musculoskeletal injury prevalence and practice frequency (times/wk). To measure the magnitude of association between variables, the Phi coefficient was calculated for 2x2 associations and Cramer's V was used whenever the distributions were outside this standard. When the dependent variable presented a dichotomous characteristic, an Odds Ratio (OR) was calculated with a confidence interval of 95%. We found a higher musculoskeletal injury prevalence in the axial skeleton (n = 52; 83.88%) in FF practitioners and in the lower limbs of ST practitioners (n = 9; 52.96%). When the physical activity level cutoff point was set at 300 minutes per week, there was a significant relationship between physical activity and training modality (p = 0.005). There was also a significant association between pain perception and musculoskeletal injury (p < 0.001). Clinical follow-up was a protective factor to being injured (OR = 0.18; CI = 0.06-0.49), and, even after multivariate analysis this significant association was maintained (OR = 0.03; CI = 0.01 - 0.08). Thus, FF practitioners reported more musculoskeletal injuries than STs, and follow-up medical or physical therapy was a protective factor to these injuries. FF practitioners also had a higher level of weekly physical activity weekly than ST practitioners. Functional fitness practitioners may be at a higher risk of injuries than those who participate in traditional strength training.

Effects of foam rolling and strength training on post exercise hypotension in normotensive women: A cross-over study.

Foam rolling (FR) has recently become very popular among athletes and recreational exercisers and is often used during warm up prior to strength training (ST) to induce self-myofascial release. The purpose was to examine the acute effects of ST and FR performed in isolation or in combination on blood pressure (BP) responses during recovery in normotensive women. Sixteen normotensive and strength trained women completed four interventions: 1) rest control (CON), 2) ST only, 3) FR only, and 4) ST immediately followed by FR (ST + FR). ST consisted of three sets of bench press, back squat, front pull-down, and leg press exercises at 80% of 10RM. FR was applied unilaterally in two sets of 120 s to each of the quadriceps, hamstring, and calf regions. Systolic (SBP) and diastolic (DBP) BP were measured before (rest) and every 10 min, for 60 min, following (Post 10-60) each intervention. Cohen's d effect sizes were calculated to indicate the magnitude effect by the formula d = Md/Sd, where Md is the mean difference and Sd is the standard deviation of differences. Cohen's d effect-sizes were defined as small (≥0.2), medium (≥0.5), and large (≥0.8). There were significant reductions in SBP for ST at Post-50 (p < 0.001; d = -2.14) and Post-60 (p < 0.001; d = -4.43), for FR at Post-60 (p = 0.020; d = -2.14), and for ST + FR at Post-50 (p = 0.001; d = -2.03) and Post-60 (p < 0.001; d = -2.38). No change in DBP was observed. The current findings suggest that ST and FR performed in isolation can acutely reduce SBP but without an additive effect. Thus, ST and FR can both be used to acutely reduce SBP and, importantly, FR can be added to a ST regimen without furthering the SBP reduction during recovery.

Acute Cardiopulmonary Response of High-Intensity Interval Training with Elastic Resistance vs. High-Intensity Interval Training on a Treadmill in Healthy Adults.

This study aims to describe and compare cardiopulmonary and subjective responses during high-intensity interval training with elastic resistance (EL-HIIT) and traditional high-intensity interval training (HIIT) sessions. Twenty-two healthy adults (27.6 ± 4.4 years) performed an EL-HIIT and a HIIT protocol consisting of 10 × 1 min at ~85% V·O2max prescribed by cardiopulmonary-specific tests. Pulmonary parameters, heart rate (HR), blood lactate, and rate of perceived exertion (RPE) were measured during exercise. Paired t-test and Cohen's d effect size were used to compare peak and average values. Two-way repeated measures ANOVA and mixed model with Bonferroni's post hoc test were used to compare each bout during the session. The EL-HIIT session showed higher peak and average values of HR, ventilation (V·E), relative and absolute oxygen uptake (V·O2), carbon dioxide production (V·CO2), and RPE than HIIT (p < 0.05). The effect size (ES) comparing HIIT and EL-HIIT was large for HR, V·E, and lactate (≥0.8) in peak values. Comparing each bout between HIIT and EL-HIIT, no difference was found in peak values (p > 0.05) during the session (excluding baseline, warm-up, and recovery). EL-HIIT presented a more pronounced cardiopulmonary and subjective response than HIIT.

Development of an Open-Source Injection Mold Monitoring System.

In the highly competitive injection molding industry, the ability to effectively collect information from various sensors installed in molds and machines is of the utmost relevance, enabling the development of data-based Industry 4.0 algorithms. In this work, an alternative to commercially available monitoring systems used in the industry was developed and tested in the scope of the TOOLING 4G project. The novelty of this system is its affordability, simplicity, real-time data acquisition and display in an intuitive Graphical User Interface (GUI), while being open-source firmware and software-based. These characteristics, and their combinations have been present in previous works, but, to the authors' knowledge, not all of them simultaneously. The system used an Arduino microcontroller-based data acquisition module that can be connected to any computer via a USB port. Software was developed, including a GUI, prepared to receive data from both the Arduino module and a second module. In the current state of development, data corresponding to a maximum of six sensors can be visualized, at a rate of 10 Hz, and recorded for later usage. These capabilities were verified under real-world conditions for monitoring an injection mold with the objective of creating the basis of a platform to deploy predictive maintenance. Mold temperature, cavity pressure, 3-axis acceleration, and extraction force data showed the system can successfully monitor the mold and allowed the clear distinction between normal and abnormal operating patterns.

Manual myofascial release and muscle energy enhances trunk flexibility and strength in recreationally resistance-trained women: Cross-over study.

The purpose of this study was to compare the effects of myofascial release and muscle energy on acute outcomes in trunk extensors active range-of-motion and strength in recreationally resistance-trained women. Seventeen apparently healthy women performed three experimental protocols using a cross-over, randomized (counterbalanced in Latin Square format), and within-subjects design: a) range-of-motion and strength test after a manual myofascial release protocol (MFR); b) flexibility and strength test after a muscle energy protocol (ME); and c) range-of-motion and strength test without myofascial release or muscle energy (control condition). Active trunk range-of-motion was measured via a sit-and-reach test and trunk extension strength via isometric dorsal dynamometer. A significant increase in range-of-motion was found for MFR (p = 0.002; d = 0.71) and ME (p < 0.001; d = 0.47) when comparing post-intervention with baseline values. Similarly, a significant increase for strength was found for MFR (p = 0.018; d = 0.10) when comparing post-intervention with baseline values. In conclusion, both techniques (MFR and ME) improved trunk range-of-motion with the sit and reach test immediately post-intervention; however, MFR showed greater magnitude increases in range-of-motion (MFR: (medium magnitude) vs ME: small magnitude). Due to the potential health implications, both (MFR and ME) responses should be among the many considerations for rehabilitation and performance exercise prescription when prescribing an exercise regimen.

HIIT is most effective than mict on glycemic control of older people with glucose metabolism impairments: A systematic review and metanalysis.

INTRODUCTION: Physical exercise can improve glucose metabolism; however, the best type, volume, intensity, and frequency aren't knowledge. High-Intensity Interval Training (HIIT), an emergent exercise type implicated as a short time-efficient exercise to improve metabolic health, needs more investigation regarding the traditional Moderate-Intensity Continuous Training (MICT). OBJECTIVE: To identify the effects of MICT and HIIT on glycemic control of older people with glucose metabolism impairments. METHODS: Our research question was based on the PICO model and the systematic review of the literature according to the guidelines of the preferred report items for systematic reviews and PRISMA meta-analyses. An extensive search was conducted in the Web of Science, PubMed, and Scielo databases. Only English language papers were included. The keywords used were "HIIT and metabolism of the elderly", "HIIT and glucose metabolism of the elderly", and "MICT and metabolism of the elderly", which were crossed with the Boolean operators "AND" and "OR" or both according to the guidelines of the PRISMA. RESULTS: Seventy papers were retrieved in the initial search. After applying all inclusions and exclusion parameters, 63 articles were excluded. In the end, six papers were classified as eligible for this study. All data categorically demonstrates that both HIIT and MICT can improve glucose metabolism with a larger effect size towards the HIIT model after the meta-analysis, pointing to HIIT as the most effective strategy. CONCLUSION: Both modalities can improve glucose metabolism in the elderly with a clear advantage for HIIT over MICT.

Effects of Different Recovery Modalities on Delayed Onset Muscle Soreness, Recovery Perceptions, and Performance Following a Bout of High-Intensity Functional Training.

The purpose of this study was to investigate the effects of the foam rolling technique and static stretching on perceptual and neuromuscular parameters following a bout of high-intensity functional training (HIFT), which consisted of 100 pull-ups, 100 push-ups, 100 sit-ups, and 100 air squats (Angie benchmark) in recreationally trained men (n = 39). Following baseline measurements (Feeling Scale, Visual Analogue Scale, Total Quality Recovery, Sit-and-Reach, Countermovement Jump, and Change-of-Direction t-test), the volunteers performed a single bout of HIFT. At the end of the session, participants were randomly assigned to one of three distinct groups: control (CONT), foam rolling (FR), or static stretching (SS). At the 24 h time-point, a second experimental session was conducted to obtain the post-test values. The level of significance was set at p < 0.05. Regarding power performance, none of the three groups reached pretest levels at 24 h point of the intervention. However, the CONT group still showed a greater magnitude of effect at the 24 h time-point (ES = 0.51, p ≥ 0.05). Flexibility presented the same recovery pattern as power performance (post × 24 h CONT = ES = 0.28, FR = ES = 0.21, SS = ES = 0.19). At 24 h, all groups presented an impaired performance in the COD t-test (CONT = ES = 0.24, FR = ES = 0.65, SS = ES = 0.56 p ≥ 0.05). The FR protocol resulted in superior recovery perceptions (pre × 24 h TQR = ES = 0.32 p ≥ 0.05). The results of the present study indicate that the use of FR and SS exercises may not be indicated when aiming to restore neuromuscular performance following a single bout of HIFT. The use of the FR technique during the cooldown phase of a HIFT session may be helpful in improving an individual's perception of recovery.

Development and Mechanical Characterization of Short Curauá Fiber-Reinforced PLA Composites Made via Fused Deposition Modeling.

The increase in the use of additive manufacturing (AM) has led to the need for filaments with specific and functional properties in face of requirements of structural parts production. The use of eco-friendly reinforcements (i.e., natural fibers) as an alternative to those more traditional synthetic counterparts is still scarce and requires further investigation. The main objective of this work was to develop short curauá fiber-reinforced polylactic acid (PLA) composites made via fused deposition modeling. Three different fiber lengths (3, 6, and 8 mm), and three concentrations in terms of weight percentage (2, 3.5, and 5 wt.%) were used to fabricate reinforced PLA filaments. Tensile and flexural tests in accordance with their respective American Society for Testing and Materials (ASTM) standards were performed. A thermal analysis was also carried out in order to investigate the thermal stability of the new materials. It was found that the main driving factor for the variation in mechanical properties was the fiber weight fraction. The increase in fiber length did not provide any significant benefit on the mechanical properties of the curauá fiber-reinforced PLA composite printed parts. The composites produced with PLA filaments reinforced by 3 mm 2% curauá fiber presented the overall best mechanical and thermal properties of all studied groups. The curauá fiber-reinforced PLA composites made via fused deposition modeling may be a promising innovation to improve the performance of these materials, which might enable them to serve for new applications.

Is There Agreement and Precision between Heart Rate Variability, Ventilatory, and Lactate Thresholds in Healthy Adults?

This study aims to analyze the agreement and precision between heart rate variability thresholds (HRVT1/2) with ventilatory and lactate thresholds 1 and 2 (VT1/2 and LT1/2) on a treadmill. Thirty-four male students were recruited. Day 1 consisted of conducting a health survey, anthropometrics, and Cardiopulmonary Exercise Test (CPx). On Day 2, after 48 h, a second incremental test was performed, the Cardiopulmonary Stepwise Exercise Test consisting of 3 min stages (CPxS), to determine VT1/2, LT1/2, and HRVT1/2. One-way repeated-measures ANOVA and effect size (ηp2) were used, followed by Sidak's post hoc. The Coefficient of Variation (CV) and Typical Error (TE) were applied to verify the precision. Bland Altman and the Intraclass Correlation Coefficient (ICC) were applied to confirm the agreement. HRVT1 showed different values compared to LT1 (lactate, RER, and R-R interval) and VT1 (V̇E, RER, V̇CO2, and HR). No differences were found in threshold 2 (T2) between LT2, VT2, and HRVT2. No difference was found in speed and V̇O2 for T1 and T2. The precision was low to T1 (CV > 12% and TE > 10%) and good to T2 (CV < 12% and TE < 10%). The agreement was good to fair in threshold 1 (VT1, LT1, HRVT1) and excellent to good in T2 (VT1, LT1, HRVT1). HRVT1 is not a valid method (low precision) when using this protocol to estimate LT1 and VT1. However, HRVT2 is a valid and noninvasive method that can estimate LT2 and VT2, showing good agreement and precision in healthy adults.

Cardiopulmonary Exercise Testing with Elastic Resistance: A New Reproducible Proposal for Determination of Ventilatory Thresholds and Maximum Oxygen Consumption.

To propose a new Cardiopulmonary Exercise Test with Elastic Resistance (CPxEL) and compare the physiological responses to conventional cardiopulmonary exercise test (CPx) performed on a treadmill. In addition, we tested the reproducibility of the CPxEL. Twenty-four physically active participants completed the CPx (first session) and CPxEL twice (second and third sessions) interspersed by seven days. A treadmill protocol with increments of 1km·h-1 every minute until exhaustion was used in CPx. The CPxEL consisted of performing alternating steps back-and-forth against an elastic resistance attached to a belt and an incremental protocol with 1 stage (S) per minute following a cadence of 200 bpm controlled by a metronome in an 8-stage rubber mat. First analysis: first ventilatory threshold (VT1) occurred at 69.7% and 75.3% of maximal heart rate (HRmax) and 53.5% and 65.7% of maximal oxygen consumption (V̇O2max). Second VT (VT2) occurred at 93.3% and 96.8% of the HRmax and 87.0% and 96.9% of V̇O2max for CPx and CPxEL, respectively. At exhaustion, V̇O2max, perceived exertion (BORG-CR10 and OMNI-RES EB), and test duration presented lower values for CPxEL (P < 0.05). Second analysis: VT1 occurred at warm-up (S0) (P = 0.731), VT2 occurred at S5 (P = 0.912), and the exhaustion occurred at S6 and S7 (P = 0.271) for CPxEL and retest, respectively. The intraclass correlation coefficient (ICC) for V̇O2max was 0.921 and for HRmax was 0.930. The CPxEL has good test-retest reproducibility and represents a possible and interesting add-on to determine maximal oxygen consumption, maximal heart rate, and second ventilatory threshold without using traditional ergometers.

Comment on Teles et al. HIIE Protocols Promote Better Acute Effects on Blood Glucose and Pressure Control in People with Type 2 Diabetes than Continuous Exercise. Int. J. Environ. Res. Public Health 2022, 19, 2601.

After a careful appraisal, we are concerned that the article "HIIE Protocols Promote Better Acute Effects on Blood Glucose and Pressure Control in People with Type 2 Diabetes than Continuous Exercise" [...].

Optimization to Assist Design and Analysis of Temperature Control Strategies for Injection Molding-A Review.

Injection molding (IM) is the most widespread and economical way to obtain high-quality plastic components. The process depends, however, to a great extent, on the quality and efficiency of the injection molding tools. Given the nature of the IM process, the temperature control system (TCS), its design, and its efficiency are of utmost importance for achieving the highest possible quality of plastic parts in the shortest possible time. For that reason, the implementation of additive manufacturing (AM) in novel IM temperature control strategies has gained considerable interest in academia and industry over the years. Conformal cooling channels (CCCs) are TCSs that have already demonstrated great potential when compared to conventional gun-drilling systems. Nevertheless, despite the recent advances, the design of these systems is still an open field of study and requires additional research in both aspects deemed as critical: thermo-mechanical models and the application of optimization techniques. This review paper tackles all the relevant, available papers on this topic, highlighting thermo-mechanical models developed by TCS designers and the optimization techniques used. The articles were thoroughly analyzed, and key points on the design of new TCS and new opportunities were identified.

McCune-Albright syndrome - A case report with transmission electron microscopy

Abstract McCune - Albright syndrome is a genetic disease with cutaneous mosaicism caused by post-zygotic activating mutations in GNAS locus, it has a triad of fibrous bone dysplasia, café-au-lait macules and precocious puberty. We examined a 22-year-old female patient with café au lait spot in right side of the abdomen, with a chessboard - like distribution, extending to right thigh with geographical contours, she has also an ovarian cyst, scoliosis and truncal obesity. Biopsies were taken from the hyperpigmented area and processed for light microscopy and for transmission electron microscopy. Light microscopy showed increased melanin pigment with HE staining. Immunohistochemistry with melanocytic markers (HMB-45 and Melan-A) revealed a normal number of melanocytes. Transmission electron microscopy demonstrated normal epidermal structures, such as desmosomes, cytokeratin filaments and hemidesmosomes. With high magnifications an irregular melanossomal contour was seen, with some indentations in their outline.

Effects of Manual Therapies and Resistance Exercise on Postexercise Hypotension in Women With Normal Blood Pressure.

ABSTRACT: Monteiro, ER, Pescatello, LS, Winchester, JB, Corrêa Neto, VG, Brown, AF, Budde, H, Marchetti, PH, Silva, JG, Vianna, JM, and Novaes, JdS. Effects of manual therapies and resistance exercise on postexercise hypotension in women with normal blood pressure. J Strength Cond Res 36(4): 948-954, 2022-The purpose of this investigation was to examine the acute effects of resistance exercise (RE) and different manual therapies (static stretching and manual massage [MM]) performed separately or combined on blood pressure (BP) responses during recovery in women with normal BP. Sixteen recreationally strength-trained women (age: 25.1 ± 2.9 years; height: 158.9 ± 4.1 cm; body mass: 59.5 ± 4.9 kg; body mass index: 23.5 ± 1.9 kg·m-2; baseline systolic BP median: 128 mm Hg; and baseline diastolic BP median: 78 mm Hg) were recruited. All subjects performed 6 experiments in a randomized order: (a) rest control (CON), (b) RE only (RE), (c) static-stretching exercise only (SS), (d) MM only, (e) RE immediately followed by SS (RE + SS), and (f) RE immediately followed by MM (RE + MM). RE consisted of 3 sets of bilateral bench press, back squat, front pull-down, and leg press exercises at 80% of 10RM. Static stretching and MM were applied unilaterally in 2 sets of 120 seconds to each of the quadriceps, hamstring, and calf regions. Systolic (SBP) and diastolic BP were measured before (rest) and every 10 minutes for 60 minutes following (Post 10-60) each intervention. There were significant intragroup differences for RE in Post-50 (p = 0.038; d = -2.24; ∆ = -4.0 mm Hg). Similarly, SBP intragroup differences were found for the SS protocol in Post-50 (p = 0.021; d = -2.67; ∆ = -5.0 mm Hg) and Post-60 (p = 0.008; d = -2.88; ∆ = -5.0 mm Hg). Still, SBP intragroup differences were found for the MM protocol in Post-50 (p = 0.011; d = -2.61; ∆ = -4.0 mm Hg) and Post-60 (p = 0.011; d = -2.74; ∆ = -4.0 mm Hg). Finally, a single SBP intragroup difference was found for the RE + SS protocol in Post-60 (p = 0.024; d = -3.12; ∆ = -5.0 mm Hg). Practitioners should be aware that SS and MM have the potential to influence BP responses in addition to RE or by themselves and therefore should be taken into consideration for persons who are hypertensive or hypotensive.