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ChemSusChem
; 12(13): 3144-3151, 2019 Jul 05.
Artículo
en Inglés
| MEDLINE
| ID: mdl-30945447
RESUMEN
A highly efficient method for the oxidative coupling of 2-substituted 3-oxindoles with aromatic compounds to form 2,2-disubstituted indolin-3-ones with broad scope is described. This work utilized oxygen as the terminal oxidant and a base-metal catalyst under mild conditions instead of toxic/precious-metal reagents and higher-molecular-weight oxidants. Quaternary structures were produced in modest-to-excellent yields (up to 96 %) without prefunctionalization.