[The systemic approach to analysis of opinions of patients about medical service].

The maintenance of health of residents of the Northern Regions of Russia, including those living in the Arctic zone of the cbountry, is a condition of its advance development in XXI century. The percentage of Russian citizen vaccinated against the new coronavirus infection (COVID-19) does not exceed 50% after beginning of implementation of vaccination program. It can be conditioned by lower level of both of credence of citizen to health care system and health literacy.Purpose of the study is to establish determinants of vaccination of population against COVID-19 in circumpolar region of Russia as exemplified by the Arkhangelsk Oblast.The sociological survey was carried out using the interview technique of patients of medical organizations (n=433) and conditionally healthy residents of the Arkhangelsk Oblast (n=139). To evaluate the level of general health literacy the Russian version of questionnaire HLS19 - Q22-RU was applied. The most of conditionally healthy respondents and consumers of medical services looked for information about methods of prevention and treatment (80.4% and 58.2% correspondingly), had an experience of vaccination against COVID-19 (79% and 56.3% correspondingly). The relative chances of conditionally healthy respondents, women, and respondents having no children and no credence to national health care system to independently look for information related to COVID-19 is higher at 2.94, 2.08, 1.55 and 1.48-1.57 times correspondingly. The relative chances of conditionally healthy respondents having no children in family and assessing one's economic status as "higher than average" to be vaccinated against COVID-19 is higher at 4.02, 1.52, 1.53 times correspondingly. Availability of experience of vaccination against COVID-19 is conditioned by higher level of general health literacy.In the Arkhangelsk Oblast and other circumpolar regions of Russia the programs of increasing loyalty of citizen to measures of population prevention, including vaccine prevention, is to be implemented with consideration of established determinants of of vaccinations against COVID-19.

Three-dimensional coherent structures of electrokinetic instability.

A direct numerical simulation of the three-dimensional elektrokinetic instability near a charge-selective surface (electric membrane, electrode, or system of micro- or nanochannels) has been carried out and analyzed. A special finite-difference method has been used for the space discretization along with a semi-implicit 31/3-step Runge-Kutta scheme for the integration in time. The calculations employ parallel computing. Three characteristic patterns, which correspond to the overlimiting currents, are observed: (a) two-dimensional electroconvective rolls, (b) three-dimensional regular hexagonal structures, and (c) three-dimensional structures of spatiotemporal chaos, which are a combination of unsteady hexagons, quadrangles, and triangles. The transition from (b) to (c) is accompanied by the generation of interacting two-dimensional solitary pulses.

[Adsorption of spin-labeled flocculants on E. coli cells]. / Izuchenie adsorbtsii spin-mechenykh flokuliantov na kletkakh E. coli.

The interaction of intact E. coli cells with polymeric flocculants polyethylenimine and dextran was being studied by spin-labelling. The nitroxyl groups of spin-labelled polymers are reduced during formation of the adsorption layer on the cell surface. Some peculiarities of redox reactions between polymer macroradicals and units of the bacterial electron-transport chain were studied depending of temperature and flocculation regime. The course of the reduction of spin-labelled polymer radicals and characteristics of EPR spectra of the flocculant give evidence on the formation of a loose polymeric layer on the surface of E. coli cells.

[Physiological activity of Escherichia coli cells studied by the spin exchange method]. / Izuchenie fiziologicheskoi aktivnosti kletok Escherichia coli metodom spinovogo obmena.

The respiration and reducing activity of Escherichia coli M-17 cells was studied at physiological temperatures using the phenomenon of spin exchange between water-soluble nitroxyl radicals and molecular oxygen in liquid bacterial media. The peak intensity of the EPR signal from nitroxyl probes was characterized by a two-stage kinetics. The first stage was due to the rapid uptake of dissolved O2 whereas the second stage was caused by the anaerobic reduction of free radicals. The maximal rates of respiration and radical reduction were found at 45 to 55 degrees C. The rate of cell respiration changed when lipids underwent a gel-liquid crystal structural transition.

[Interaction of divalent copper ions with the cell surface of Escherichia coli studied by spin exchange]. / Izuchenie vzaimodeistviia ionov dvukhvalentnoi medi s kletochnoi poverkhnost'iu Escherichia coli metodom spinovogo obmena.

The binding of cupric ions to the surface ionogenic groups of Escherichia coli was studied by the method of spin exchange. The formation of coordination complexes between these groups and cupric ions inhibited the physiological activity of the cells by interfering with the operation of their electron-transport chain.