Frequency-dependent dynamics of steady-state visual evoked potentials under sustained flicker stimulation.

Steady-state visual evoked potentials (SSVEP) are electroencephalographic signals elicited when the brain is exposed to a visual stimulus with a steady frequency. We analyzed the temporal dynamics of SSVEP during sustained flicker stimulation at 5, 10, 15, 20 and 40 Hz. We found that the amplitudes of the responses were not stable over time. For a 5 Hz stimulus, the responses progressively increased, while, for higher flicker frequencies, the amplitude increased during the first few seconds and often showed a continuous decline afterward. We hypothesize that these two distinct sets of frequency-dependent SSVEP signal properties reflect the contribution of parvocellular and magnocellular visual pathways generating sustained and transient responses, respectively. These results may have important applications for SSVEP signals used in research and brain-computer interface technology and may contribute to a better understanding of the frequency-dependent temporal mechanisms involved in the processing of prolonged periodic visual stimuli.

Temporal Modulation of Steady-State Visual Evoked Potentials.

Electroencephalographic responses to periodic stimulation are termed steady-state visual evoked potentials (SSVEP). Their characteristics in terms of amplitude, frequency and phase are commonly assumed to be stationary. In this work, we tested this assumption in 30 healthy participants submitted to 50 trials of 60 s flicker stimulation at 15 Hz frequency. We showed that the amplitude of the first and second harmonic frequency components of SSVEP signals were in general not stable over time. The power (squared amplitude) of the fundamental component was stationary only in 30% the subjects, while the power at the second harmonic frequency was stationary in 66.7% of the group. The phases of both SSVEP frequency components were more stable over time, but could exhibit small drifts. The observed temporal changes were heterogeneous across the subjects, implying that averaging results over participants should be performed carefully. These results may contribute to improved design and analysis of experiments employing prolonged visual stimulation. Our findings offer a novel characterization of the temporal changes of SSVEP that may help to identify their physiological basis.