[Clinical and pathogenetic aspects of the chronic occupational intoxication with fluorine compounds in modern reality].

Multi-year follow-up of 358 workers of aluminum pot rooms, including 165 individuals suffering from fluorosis, has shown significant changes in the clinical picture of the chronic occupational fluorine intoxication, developed under modern conditions of production, at lower concentrations of fluorine compounds in the air of working area. In this connection, the pathology of the musculoskeletal system plays the dominating role in this clinical picture and has the large variability of combinations of the individual sections destructions of the bone tissue. The main criterion to establish the phase of the disease is still the number and severity of the signs of this destruction. The visceral pathology in contemporary production circumstances is registered with less frequency and loses a number of the previously described clinical manifestations, however, is still of some importance to identify the early signs of the disease and to prevent the dental fluorosis on time.

[Changes in fluorosis clinical manifestations under treatment and during post-contact period].

The article covers results of health state monitoring in patients with fluorosis stages I and II, who remain or continue contact with fluor and its compounds. The author evaluated treatment efficiency for fluorosis patients and risk group members, demonstrated efficiency of therapy designed with consideration of biologic rhythms in various body systems, clinical manifestations and the disease pathogenesis.