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1.
Gan To Kagaku Ryoho ; 42(12): 1591-3, 2015 Nov.
Artículo en Japonés | MEDLINE | ID: mdl-26805106

RESUMEN

We present a successful case of treatment of colonic metastasis and peritoneal recurrence of type 4 gastric cancer by using colectomy and chemotherapy. A 70-year-old woman with a diagnosis of type 4 advanced gastric cancer underwent distal gastrectomy. The final pathological diagnosis was LM, circ, type 4, sig, pT4a (SE), ly1, v1, pN1, M0, P0, CY0, pStage Ⅲa. Adjuvant chemotherapy was conducted with oral administration of S-1, though regrettably the chemotherapy was interrupted because of diarrhea, an adverse effect of S-1. Metastatic recurrence occurred on the transverse colon, for which she underwent transverse colectomy 2.9 years after the initial surgery. Another colonic metastasis in the ascending colon along with peritoneal recurrence was diagnosed 3.11 years after the initial surgery, and the patient underwent a palliative colostomy and received chemotherapy with S-1 plus docetaxel. She was successfully treated up to a clinical CR with chemotherapy, and she died 5.10 years after the initial surgery. In this case, a good prognosis was obtained through the combination of resection of the recurrence sites, palliative surgery for avoiding obstruction, and chemotherapy using S-1 plus docetaxel for metachronous multiple metastases.


Asunto(s)
Neoplasias del Colon/secundario , Neoplasias Gástricas/patología , Anciano , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapéutico , Quimioterapia Adyuvante , Colectomía , Neoplasias del Colon/tratamiento farmacológico , Neoplasias del Colon/cirugía , Docetaxel , Combinación de Medicamentos , Resultado Fatal , Femenino , Humanos , Ácido Oxónico/administración & dosificación , Recurrencia , Neoplasias Gástricas/tratamiento farmacológico , Neoplasias Gástricas/cirugía , Taxoides/administración & dosificación , Tegafur/administración & dosificación
2.
Gan To Kagaku Ryoho ; 42(12): 2343-5, 2015 Nov.
Artículo en Japonés | MEDLINE | ID: mdl-26805358

RESUMEN

A 57-year-old woman was diagnosed with a pancreatic tumor. Abdominal computed tomography showed cStage Ⅳa pancreatic cancer with a 20×16 mm tumor near the base of the celiac artery. Since the tumor contacted the SMA at an angle of 90 degrees, it was judged as a borderline resectable tumor. In addition, cStage ⅠB gastric cancer was found in the corpus ventriculi. Since the patient had a respiratory complication, a distal pancreatectomy with celiac axis resection in combination with a total gastrectomy was considered too aggressive for this patient. Therefore, she received chemoradiotherapy prior to the surgery. Distal pancreatectomy with D2 lymphadenectomy and subtotal gastrectomy with lower left phrenic artery preservation was performed. This case involved a considerable extension of the disease and radical surgery; however, currently the patient's prognosis and QOL are good.


Asunto(s)
Neoplasias Primarias Múltiples/terapia , Neoplasias Pancreáticas/terapia , Neoplasias Gástricas/terapia , Quimioradioterapia , Femenino , Gastrectomía , Humanos , Persona de Mediana Edad , Estadificación de Neoplasias , Neoplasias Primarias Múltiples/patología , Pancreatectomía , Neoplasias Pancreáticas/patología , Pronóstico , Neoplasias Gástricas/patología
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