Gross and microscopic features in chancroid: a study in 200 new culture-proven cases in San Salvador.

BACKGROUND AND OBJECTIVES: A better knowledge of gross and microscopic features in chancroid are important in this increased frequency disease. STUDY DESIGN: Two biopsies were taken from each one of 200 culture-proven cases of chancroid, and studied through different stains. RESULTS: The ratio male/female was 15.7/1, and adenopathies were found in 87%. Biopsies showed edema, lymphohistiocytic inflammation and fibrinoid vasculitis, as well as the presence of numerous eosinophils and Russell bodies. CONCLUSION: Biopsy should be considered as an important tool for the diagnostic of chancroid.