Asunto(s)
Anticuerpos Monoclonales/uso terapéutico , Dermatitis Alérgica por Contacto/etiología , Dermatitis Atópica/complicaciones , Fármacos Dermatológicos/uso terapéutico , Resinas de Plantas/efectos adversos , Adulto , Anticuerpos Monoclonales/efectos adversos , Anticuerpos Monoclonales Humanizados , Dermatitis Atópica/tratamiento farmacológico , Fármacos Dermatológicos/efectos adversos , Femenino , Humanos , Pruebas del ParcheRESUMEN
We report a case of a 65-year-old man who developed an asymptomatic bluish spot that affected the flank and left lumbar region with the onset 10 years prior. He had a history of diffuse systemic sclerosis with anti-Scl-70-positive antibodies. The appearance of the skin lesion coincided with the onset of his disease. The skin biopsy was consistent with the diagnosis of acquired dermal melanocytosis. The relationship between the appearance of acquired pigmented macules and spots and systemic sclerosis has been known for years, although it is an infrequent finding.
Asunto(s)
Melanosis/complicaciones , Esclerodermia Difusa/complicaciones , Anciano , Humanos , Masculino , Población BlancaRESUMEN
No disponible
Asunto(s)
Humanos , Masculino , Anciano de 80 o más Años , Arteritis de Células Gigantes/diagnóstico , Necrosis/patología , Piel/lesiones , Arterias Temporales/fisiopatología , Arteritis de Células Gigantes/tratamiento farmacológico , Arteritis de Células Gigantes/patología , Proteína C-Reactiva/uso terapéuticoRESUMEN
Bier anaemic spots, cyanosis with urticaria-like eruption syndrome is a recently described benign vasomotor dermatosis that mainly affects the lower limbs. Histopathology shows multiple dilated dermal vessels with scattered eosinophils. We report a case on the trunk and upper limbs.
Asunto(s)
Enfermedades Cutáneas Vasculares/diagnóstico , Piel/patología , Niño , Cianosis/etiología , Exantema/etiología , Humanos , Masculino , Enfermedades Cutáneas Vasculares/patología , Síndrome , Torso/patología , Extremidad Superior/patología , Urticaria/etiologíaAsunto(s)
Toxinas Botulínicas Tipo A/uso terapéutico , Enfermedad de Darier/diagnóstico , Enfermedad de Darier/tratamiento farmacológico , Progresión de la Enfermedad , Adulto , Nalgas , Esquema de Medicación , Estudios de Seguimiento , Humanos , Región Lumbosacra , Masculino , Índice de Severidad de la Enfermedad , Resultado del TratamientoAsunto(s)
Ciclosporina/uso terapéutico , Glucagonoma/complicaciones , Eritema Necrolítico Migratorio/tratamiento farmacológico , Neoplasias Pancreáticas/complicaciones , Fármacos Dermatológicos/uso terapéutico , Glucagonoma/diagnóstico , Humanos , Masculino , Persona de Mediana Edad , Eritema Necrolítico Migratorio/diagnóstico , Eritema Necrolítico Migratorio/etiología , Neoplasias Pancreáticas/diagnóstico , Síndromes Paraneoplásicos/complicaciones , Síndromes Paraneoplásicos/diagnósticoRESUMEN
No disponible
Asunto(s)
Humanos , Masculino , Persona de Mediana Edad , Síndrome de Schnitzler/diagnóstico , Exantema/etiología , Prurito/etiología , Interleucina-1/antagonistas & inhibidores , Antagonistas de los Receptores Histamínicos/uso terapéuticoRESUMEN
Prurigo nodularis (PN) is an intensely pruriginous dermatological disorder whose treatment is challenging for dermatologists. It is characterized by eruptions of papules and hyperkeratotic nodules, some of which are eroded, on the extensor surfaces of the limbs. The most commonly used treatments for this condition are oral antihistamines and topical or systemic steroids. Thalidomide is an effective treatment option in cases of recalcitrant PN; however, its most frequent adverse effect is neurotoxicity, which often results in its discontinuation. Lenalidomide is an analogue of thalidomide that is more powerful and associated with less neurotoxicity than thalidomide. We report the third case of PN treated with lenalidomide, which involved a patient who was refractory to thalidomide. Lenalidomide may be a more effective treatment for PN than thalidomide and has a more favorable side effects profile than its counterpart.