RESUMEN
A case of pyoderma gangrenosum that occurred in the absence of underlying illness and was initially misdiagnosed is described. Hemorrhagic pustules and ulcers appeared over vein-graft sites after open heart surgery and were treated with cyclosporine. The result was rapid and complete resolution. It is the purpose of this report to emphasize pyoderma gangrenosum as a cause of ulceration in healthy individuals and to highlight the addition of cyclosporine to the therapeutic armamentarium.
Asunto(s)
Ciclosporina/uso terapéutico , Piodermia Gangrenosa/tratamiento farmacológico , Humanos , Masculino , Persona de Mediana Edad , Piodermia Gangrenosa/patologíaRESUMEN
Lancefield group G streptococcus is now recognized as a pathogen and has been reported to cause severe infections, including meningitis. We describe the first case of meningitis caused by this organism in a patient with acquired immunodeficiency syndrome (AIDS) and the direct transmission of the pathogen to a technologist accidentally exposed to the cerebrospinal fluid. To prove the identity of the two strains, we have tested them employing the Vitek system. We have also tested 13 other strains of group G streptococci obtained from different sources. Our results yielded 14 different biotypes with the 15 strains tested. The only identical ones were the two suspect strains from the index case and the technologist. We conclude that the biotyping system employed in our study appears to be a useful epidemiological tool for marking group G streptococci.
Asunto(s)
Síndrome de Inmunodeficiencia Adquirida/complicaciones , Infección de Laboratorio/microbiología , Meningitis/microbiología , Infecciones Estreptocócicas/microbiología , Streptococcus/clasificación , Técnicas de Tipificación Bacteriana , Femenino , Humanos , Masculino , Meningitis/complicaciones , Persona de Mediana Edad , Faringitis/microbiología , Infecciones Estreptocócicas/complicacionesRESUMEN
Staphylococcus aureus has been reported to cause a high number of infections and septicemias, often related to intravenous catheters, in patients with acquired immunodeficiency syndrome (AIDS). Our objective was to assess the frequency of S. aureus nasal carriage among patients with AIDS or AIDS-related complex (ARC). The nasal carriage rate of S. aureus was determined within 24 hours of admission in 64 consecutively hospitalized patients with AIDS or ARC. Intravenous drug abusers were excluded. A control group of 64 patients with other diseases was also tested. Of 64 patients with AIDS or ARC, 35 (55%) were nasal carriers of S. aureus, compared with 18 (28%) of 64 control patients. Recent hospitalization did not influence carriage rate, nor did the recent use of antibiotics or zidovudine. The significant S. aureus carriage rate in patients with AIDS or ARC may contribute to the high incidence of intravenous catheter-related S. aureus infections in this population.
