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Nouv Rev Fr Hematol (1978) ; 27(1): 11-4, 1985.
Artículo en Francés | MEDLINE | ID: mdl-3991355

RESUMEN

Epidemiologic programs in Martinique during the last 10 years and particularly the last 5, have allowed the determination of the Hb S, Hb C, beta thalassemia traits frequencies. A number of rare variants have been detected during the course of these screening programs. Many of these Hb variants have been analysed at the structural level. For some of them a pathologic interaction with Hb S is observed (Hb D Punjab, Hb O Arab...), and the use of electrophoretic mobilities obtained with the reference samples provides the basis of a rapid, highly probable presumptive identification and then, a useful tool, when for example genetic counselling is necessary.


Asunto(s)
Hemoglobinas Anormales/aislamiento & purificación , Métodos Epidemiológicos , Hemoglobina C/aislamiento & purificación , Hemoglobina Falciforme/aislamiento & purificación , Hemoglobinas Anormales/genética , Humanos , Recién Nacido , Focalización Isoeléctrica , Martinica , Fenotipo , Rasgo Drepanocítico/sangre , Talasemia/sangre
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