Quantum-like modeling in biology with open quantum systems and instruments.

We present the novel approach to mathematical modeling of information processes in biosystems. It explores the mathematical formalism and methodology of quantum theory, especially quantum measurement theory. This approach is known as quantum-like and it should be distinguished from study of genuine quantum physical processes in biosystems (quantum biophysics, quantum cognition). It is based on quantum information representation of biosystem's state and modeling its dynamics in the framework of theory of open quantum systems. This paper starts with the non-physicist friendly presentation of quantum measurement theory, from the original von Neumann formulation to modern theory of quantum instruments. Then, latter is applied to model combinations of cognitive effects and gene regulation of glucose/lactose metabolism in Escherichia coli bacterium. The most general construction of quantum instruments is based on the scheme of indirect measurement, in that measurement apparatus plays the role of the environment for a biosystem. The biological essence of this scheme is illustrated by quantum formalization of Helmholtz sensation-perception theory. Then we move to open systems dynamics and consider quantum master equation, with concentrating on quantum Markov processes. In this framework, we model functioning of biological functions such as psychological functions and epigenetic mutation.

Application of Theory of Quantum Instruments to Psychology: Combination of Question Order Effect with Response Replicability Effect.

Recently, quantum formalism started to be actively used outside of quantum physics: in psychology, decision-making, economics, finances, and social science. Human psychological behavior is characterized by a few basic effects; one of them is the question order effect (QOE). This effect was successfully modeled (Busemeyer-Wang) by representing questions A and B by Hermitian observables and mental-state transformations (back action of answering) by orthogonal projectors. However, then it was demonstrated that such representation cannot be combined with another psychological effect, known as the response replicability effect (RRE). Later, this no-go result was generalized to representation of questions and state transformations by quantum instruments of the atomic type. In light of these results, the possibility of using quantum formalism in psychology was questioned. In this paper, we show that, nevertheless, the combination of the QOE and RRE can be modeled within quantum formalism, in the framework of theory of non-atomic quantum instruments.

Experimental Test of Residual Error-Disturbance Uncertainty Relations for Mixed Spin-½ States.

The indeterminacy inherent in quantum measurements is an outstanding character of quantum theory, which manifests itself typically in the uncertainty principle. In the last decade, several universally valid forms of error-disturbance uncertainty relations were derived for completely general quantum measurements for arbitrary states. Subsequently, Branciard established a form that is optimal for spin measurements for some pure states. However, the bound in his inequality is not stringent for mixed states. One of the present authors recently derived a new bound tight in the corresponding mixed state case. Here, a neutron-optical experiment is carried out to investigate this new relation: it is tested whether error and disturbance of quantum measurements disappear or persist in mixing up the measured ensemble. The attainability of the new bound is experimentally observed, falsifying the tightness of Branciard's bound for mixed spin states.

Erratum: Experimental Test of Entropic Noise-Disturbance Uncertainty Relations for Spin-1/2 Measurements [Phys. Rev. Lett. 115, 030401 (2015)].

This corrects the article DOI: 10.1103/PhysRevLett.115.030401.

Experimental Test of Entropic Noise-Disturbance Uncertainty Relations for Spin-1/2 Measurements.

Information-theoretic definitions for noise and disturbance in quantum measurements were given in [Phys. Rev. Lett. 112, 050401 (2014)] and a state-independent noise-disturbance uncertainty relation was obtained. Here, we derive a tight noise-disturbance uncertainty relation for complementary qubit observables and carry out an experimental test. Successive projective measurements on the neutron's spin-1/2 system, together with a correction procedure which reduces the disturbance, are performed. Our experimental results saturate the tight noise-disturbance uncertainty relation for qubits when an optimal correction procedure is applied.

Noise and disturbance in quantum measurements: an information-theoretic approach.

We introduce information-theoretic definitions for noise and disturbance in quantum measurements and prove a state-independent noise-disturbance tradeoff relation that these quantities have to satisfy in any conceivable setup. Contrary to previous approaches, the information-theoretic quantities we define are invariant under the relabelling of outcomes and allow for the possibility of using quantum or classical operations to "correct" for the disturbance. We also show how our bound implies strong tradeoff relations for mean square deviations.

Experimental test of error-disturbance uncertainty relations by weak measurement.

We experimentally test the error-disturbance uncertainty relation (EDR) in generalized, strength-variable measurement of a single photon polarization qubit, making use of weak measurement that keeps the initial signal state practically unchanged. We demonstrate that the Heisenberg EDR is violated, yet the Ozawa and Branciard EDRs are valid throughout the range of our measurement strength.

Experimental violation and reformulation of the Heisenberg's error-disturbance uncertainty relation.

The uncertainty principle formulated by Heisenberg in 1927 describes a trade-off between the error of a measurement of one observable and the disturbance caused on another complementary observable such that their product should be no less than the limit set by Planck's constant. However, Ozawa in 1988 showed a model of position measurement that breaks Heisenberg's relation and in 2003 revealed an alternative relation for error and disturbance to be proven universally valid. Here, we report an experimental test of Ozawa's relation for a single-photon polarization qubit, exploiting a more general class of quantum measurements than the class of projective measurements. The test is carried out by linear optical devices and realizes an indirect measurement model that breaks Heisenberg's relation throughout the range of our experimental parameter and yet validates Ozawa's relation.

Conservative quantum computing.

The Wigner-Araki-Yanase theorem shows that conservation laws limit the accuracy of measurement. Here, we generalize the argument to show that conservation laws limit the accuracy of quantum logic operations. A rigorous lower bound is obtained of the error probability of any physical realization of the controlled-NOT gate under the constraint that the computational basis is represented by a component of spin, and that physical implementations obey the angular momentum conservation law. The lower bound is shown to be inversely proportional to the number of ancilla qubits or the strength of the external control field.

Conservation laws, uncertainty relations, and quantum limits of measurements.

The uncertainty relation between the noise operator and the conserved quantity leads to a bound on the accuracy of general measurements. The bound extends the assertion by Wigner, Araki, and Yanase that conservation laws limit the accuracy of "repeatable," or "nondisturbing," measurements to general measurements, and improves the one previously obtained by Yanase for spin measurements. The bound represents an obstacle to making a small quantum computer.