Successful surgical treatment of medically refractory epilepsy after chemotherapy in a child with leukemia: a case report.

INTRODUCTION: Mesial temporal sclerosis associated with acute lymphoblastic leukemia has been rarely reported. CASE REPORT: We report a case of a 15-year-old boy with acute lymphoblastic leukemia who developed medically refractory temporal lobe epilepsy in a long time period after chemotherapy, and successfully treated with surgical resection. CONCLUSIONS: To our knowledge, this is the first description of a leukemic child with medically refractory temporal lobe epilepsy who achieved seizure-freedom postoperatively during the long-term follow-up. The clinical history and details of the underlying pathophysiological background and treatment of this complication are discussed in this case report.