RESUMEN
INTRODUCTION: Acrylates are widely used low-molecular-weight substances, initially introduced in industry in the 1930s and subsequently applied also in medicine and the home. One of their main features is the ability to undergo polymerization. The most commonly used acrylic compounds are cyanoacrylates, methacrylates, and acrylates. OBJECTIVE: To confirm suspicion of occupational disease in a group of workers in an elevator factory. MATERIAL AND METHODS: We studied 8 patients with dermatitis of the hands and finger pads. In their work, the patients came into contact with acrylates. Patch testing was applied with an acrylate panel (BIAL-Aristegui, Bilbao, Spain). RESULTS: Seven of the patients (87. 5%) had a positive result with 1% ethylene glycol dimethacrylate. Positive RESULTS: were also observed for 2% hydroxyethyl methacrylate (5 patients, 62. 5%), 1% triethylene glycol dimethacrylate (4 patients, 50%), 10% ethyl methacrylate monomer (3 patients, 37. 5%), 10% methyl methacrylate monomer (2 patients, 25%), 1% ethyl acrylate (1 patient, 12. 5%), and 0. 1% acrylic acid (1 patient, 12. 5%). CONCLUSIONS: We highlight the strong sensitizing capacity of acrylates and the importance of taking all necessary preventive measures in industries where these substances are used. Such measures should include avoidance of contact with the product in cases where sensitization has been confirmed.
Asunto(s)
Acrilatos/toxicidad , Dermatitis por Contacto/diagnóstico , Dermatitis por Contacto/etiología , Enfermedades Profesionales/inducido químicamente , Enfermedades Profesionales/diagnóstico , Adulto , Humanos , Masculino , Persona de Mediana EdadAsunto(s)
Alérgenos/efectos adversos , Anethum graveolens/efectos adversos , Dermatitis Alérgica por Contacto/diagnóstico , Extractos Vegetales/efectos adversos , Urticaria/diagnóstico , Adulto , Dermatitis Alérgica por Contacto/etiología , Diagnóstico Diferencial , Ensayo de Inmunoadsorción Enzimática , Femenino , Humanos , Inmunoglobulina E/sangre , Pruebas Intradérmicas , Pruebas del Parche , Urticaria/inducido químicamenteAsunto(s)
Dermatitis Alérgica por Contacto/etiología , Dermatitis Profesional/etiología , Poaceae/efectos adversos , Semillas/efectos adversos , Alérgenos/efectos adversos , Animales , Aves , Dermatitis Alérgica por Contacto/diagnóstico , Dermatitis Profesional/diagnóstico , Estudios de Seguimiento , Dermatosis de la Mano/diagnóstico , Dermatosis de la Mano/etiología , Humanos , Masculino , Persona de Mediana Edad , Ocupaciones , Pruebas del Parche , Recurrencia , Medición de RiesgoRESUMEN
Many works have dealt with the study of the allergenic relevance of profilin from allergenic extracts, mainly derived from pollens and vegetable foods. Olive pollen extracts also contain a profilin allergen (Ole e 2). This protein has been characterized in detail, so the amino-acid sequence of three isoforms and the structural model of one of them are already known. The prevalence of Ole e 2 for olive allergenic patients has been evaluated by different in vivo and in vitro methods, and the results compared with those obtained for another pollen profilins.