The Effect of Repeated Shoulder Motion on Scapular Dyskinesis in Army ROTC Cadets.

INTRODUCTION: Altered or abnormal scapular motion has been associated with increased shoulder pain and dysfunction. Fatigue of the scapular stabilizing muscles resulting from repeated arm motion has been reported to alter scapular kinematics, which could result in the clinical assessment of scapular dyskinesis. The purpose of this study was to characterize the effect of repeated arm motion on the development of scapular dyskinesis. The hypothesis was that repeated arm motion will induce a subtle or obvious scapular dyskinesis. MATERIALS AND METHODS: About 30 army Reserve Officer Training Corps (ROTC) cadets participated in the research study. The cadets level of shoulder function was determined using the Quick Disabilities of the Arm Shoulder and Hand and Pennsylvania Shoulder Score shoulder scores. Cadets performed an exercise protocol of 30 repetitions of weighted shoulder motion in the frontal plane. Shoulder and scapular musculature strength measurements were recorded prior to and immediately following the exercise protocol using hand-held dynamometry. The scapular dyskinesis test was performed prior to the exercise protocol and during the last five repetitions of the exercise protocol. RESULTS: Prior to the exercise, protocol 3/30 were categorized with scapular dyskinesis on the left side and 3/30 were categorized with scapular dyskinesis on their right side. Following the exercise, protocol 8/30 were categorized with left-side scapular dyskinesis (χ2 = 9.167, P = 0.002) and 6/30 with right-side dyskinesis (χ2 = 4.537, P = 0.033). Shoulder strength decreased following the exercise protocol for all participants. The participants that developed scapular dyskinesis were weaker than those with normal scapular motion. However, the difference did not reach statistical significance. Participants graded with obvious scapular dyskinesis following the exercise protocol reported higher Quick Disabilities of the Arm Shoulder and Hand scores (P = 0.04) and lower scores on the Pennsylvania Shoulder Score (P = 0.005). CONCLUSIONS: Repeated shoulder motion increased the frequency of scapular dyskinesis in army ROTC cadets. The cadets that developed scapular dyskinesis also reported greater disability and lower function of the upper extremity. The results provide a link between scapular dyskinesis, upper extremity function, and the strength of the scapular stabilizing muscles. Improving the strength of the scapular stabilizing musculature might reduce the effects of repeated arm motions.

Simulation of the effect of hydrogen bonds on water activity of glucose and dextran using the Veytsman model.

Carbohydrates exhibit either van der Waals and ionic interactions or strong hydrogen bonding interactions. The prominence and large number of hydrogen bonds results in major contributions to phase behavior. A thermodynamic framework that accounts for hydrogen bonding interactions is therefore necessary. We have developed an extension of the thermodynamic model based on the Veytsman association theory to predict the contribution of hydrogen bonds to the behavior of glucose-water and dextran-water systems and we have calculated the free energy of mixing and its derivative leading to chemical potential and water activity. We compared our calculations with experimental data of water activity for glucose and dextran and found excellent agreement far superior to the Flory-Huggins theory. The validation of our calculations using experimental data demonstrated the validity of the Veytsman model in properly accounting for the hydrogen bonding interactions and successfully predicting water activity of glucose and dextran. Our calculations of the concentration of hydrogen bonds using the Veytsman model were instrumental in our ability to explain the difference between glucose and dextran and the role that hydrogen bonds play in contributing to these differences. The miscibility predictions showed that the Veytsman model is also able to correctly describe the phase behavior of glucose and dextran.

Molecular dynamic simulations and vibrational analysis of an ionic liquid analogue.

Deep eutectic solvents, considered ionic liquid (IL) analogues, show promise for many material science and engineering applications over typical ILs because they are readily available and relatively inexpensive. Atomistic molecular dynamics simulations have been performed over a range of temperatures on one eutectic mixture, 1:2 choline chloride/urea, using different force field modifications. Good agreement was achieved between simulated density, volume expansion coefficient, heat capacity, and diffusion coefficients and experimental values in order to validate the best performing force field. Atom-atom and center-of-mass radial distribution functions are discussed in order to understand the atomistic interactions involved in this eutectic mixture. Experimental infrared (IR) spectra are also reported for choline chloride-urea mixtures, and band assignments are discussed. The distribution of hydrogen-bond interactions from molecular simulations is correlated to curve-resolved bands from the IR spectra. This work suggests that there is a strong interaction between the NH2 of urea and the chlorine anion where the system wants to maximize the number of hydrogen bonds to the anion. Additionally, the disappearance of free carbonyl groups upon increasing concentrations of urea suggests that at low urea concentrations, urea will preferentially interact with the anion through the NH2 groups. As this concentration increases, the complex remains but with additional interactions that remove the free carbonyl band from the spectra. The results from both molecular simulations and experimental IR spectroscopy support the idea that key interactions between the moieties in the eutectic mixture interrupt the main interactions within the parent substances and are responsible for the decrease in freezing point.

Application of generalized two-dimensional infrared correlation spectroscopy to the study of a hydrogen-bonded blend.

In the preceding studies in this series, generalized two-dimensional (2D) infrared correlation spectroscopy has been applied to the study of polymer blends with relatively weak intermolecular interactions. In this paper, a miscible system with strong intermolecular interactions, hydrogen-bonded blends of poly(4-vinyl phenol) (PVPh) and poly(methyl methacrylate) (PMMA), is considered. It has been found that band positions in 2D plots are dependent on the data sets used, due to large peak shifts and/or bandwidth changes. This observation complements our preceding studies, in which it was found that new features correspond to maxima, minima, or points of inflection in the difference spectra used to generate the 2D plots and are not normal modes of vibration of specific functional groups. Great care needs to be taken in order not to interpret artifacts of the procedure in terms of new spectroscopic features.