1.
Chinese Pharmacological Bulletin
; (12): 896-902, 2023.
Artículo
en Chino
| WPRIM (Pacífico Occidental)
| ID: wpr-1013915
RESUMEN
Aim To investigate the effects of total flavonoids from Rosa rugosa (TFR) on cerebral ischemia reperfusion injury (CIRI) in rats, and to investigate whether TFR inhibited neuronal apoptosis by regulating phosphoinositide 3-kinase/protein kinase B (PI3K/AKT) signaling pathway and endoplasmic reticulum stress (ERS) pathways. Methods SD rats were randomly divided into sham operation group, model group, low-dose group (50 mg · kg