A new serovar and a new serological variant belonging to Salmonella enterica subspecies diarizonae.

Description of a new serovar (S. IIIb 16:k:e,n,x,z15) and a new serological variant (S. IIIb 42:z10:e,n,x,z15:z60 ) belonging to the genus Salmonella isolated from stool specimens of Brazilian snakes (Crotalus durissus).

A new serovar and a new serological variant belonging to Salmonella enterica subspecies diarizonae

Description of a new serovar (S. IIIb 16:k:e,n,x,z15) and a new serological variant (S. IIIb 42:z10:e,n,x,z15:z60 ) belonging to the genus Salmonella isolated from stool specimens of Brazilian snakes (Crotalus durissus)

Evaluation of a balanced fresh paste diet for maintenance of captive neotropical rattlesnakes used for venom production.

OBJECTIVE: To evaluate efficacy of a balanced fresh paste diet for maintenance of captive neotropical rattlesnakes used for venom production. DESIGN: Controlled clinical trial. ANIMALS: 40 healthy neotropical rattlesnakes. PROCEDURE: Rattlesnakes were force-fed once per week (10% of body weight) for 19 weeks; 20 control snakes received dead mice, whereas 20 test snakes received a balanced fresh paste diet. Ecdysis rates were calculated, and body weight was recorded weekly. After 19 weeks, venom was extracted and analyzed. RESULTS: Sickness or deaths were not observed; weight loss during ecdysis and weight gain overall were similar between groups. Snakes fed the balanced fresh paste diet had similar ecdysis frequency, venom potency, and protein concentration in venom as did snakes fed mice. CONCLUSIONS AND CLINICAL RELEVANCE: Results suggest that a balanced fresh paste diet has sufficient nutritional value to avoid weight loss and death and does not adversely affect venom quality in captive neotropical rattlesnakes.

[Orthotopic ileal neobladders in men and women: techniques and comparison]. / Le neovesciche ileali ortotopiche nell'uomo e nella donna: tecniche a confronto.

PURPOSE: evaluation of results and complications of ileal orthotopic neobladders in men and women with transitional cell carcinoma. MATERIALS AND METHODS: between 12-89 and 12-95 we performed 146 radical cystectomy for bladder neoplasm, in 32 patients we can perform ileal orthotopic neobladder, 29 were male and 3 were female. Oncologic indications to this kind of operation were: clinical stage T2, T3a, T3b, T1G3 multicentric and or recurrence, absence of metastasis absence of nodal metastasis, negativity of urethral biopsy. General contraindications were urethral stenosis and incontinence. Oncological contraindications, in woman, were bladder neck neoplasm or urethral neoplasm. In 4 patients we use Camey II technique, in 19 pts we performed the paduan ileal neobladder, in 9 pts we use Hautmann technique. 7 patients performed neoadjuvant chemotherapy with 4 circles of MVAC, 4 pts underwent adjuvant chemotherapy, and 2 pts salvage chemotherapy. In woman we take care during cystectomy to dissect cardinal ligament very close to cervix uteri, to resect the uterosacral ligament far to the sacrum. We did not dissect under the ureter and we cut the urethra 0.5-1 cm far from the bladder neck. RESULTS: follow up was between 6 and 66 months. 24 patients are now alive and disease free, 2 patients are alive with disease progression, 1 have a pelvic recurrence and 1 have pulmonary recurrence. 4 pts died for disease progression and 2 for non oncological cause, quality of life was considered as regard to continence and sexual activity. 1 pts was completely incontinent and 1 pts has nocturnal incontinence with a daily micturation every 1 hour. We can evaluate only 18 patients for sexual activity and 4 reported normal erection. COMPLICATIONS: in three cases we had to reoperate for early complications due to mechanical bowel obstruction, ileocutaneous fistula and wound dehiscence. In three cases we had the formation of stones, in two patients ureteroileal stenosis, in two cases urethro-ileal stenosis and 1 reflux from the neobladder. Orthotopic ileal neobladder allows a very good quality of life and is the first choice derivation after radical cystectomy.

[Terazosin in the treatment of benign prostatic hypertrophy]. / La terazosina nella terapia dell'ipertrofia prostatica benigna.

Benign prostatic hypertrophy provokes clinical manifestations correlated on one hand to a static obstructive component, due to the increase in glandular size, and on the other hand to a dynamic component, controlled by the alpha adrenergic autonomic system which gives the smooth muscular tonus of the prostatic adenoma. The alpha adrenergic receptor block reduces the dynamic component, improves the clinical and urodynamic parameters determined by the infra-bladder obstruction in patients with BPH. The selective alpha 1, long acting antagonists especially, such as terazosin, offer a safe and efficient therapy for selected patients suffering from BPH. They also have the indisputable benefit of mono-administration. In this study the basic concepts of BPH treatment with terazosin are discussed.