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Clin Neuropharmacol ; 40(1): 43-47, 2017.
Artículo en Inglés | MEDLINE | ID: mdl-27879550

RESUMEN

OBJECTIVE: The aim of this study was to report the case of a male patient with Parkinson disease who developed brachial plexopathy (BP) due to varicella-zoster virus, which was successfully treated with human immunoglobulin. METHOD: We report the case of a 75-year-old male subject with a diagnosis of Parkinson disease who came to our hospital complaining of pain, skin lesions, and strength loss in his right arm during the past 2 months. Physical examination revealed vesicular rash compatible with varicella-zoster virus lesions. Nerve conduction studies and magnetic resonance imaging of the brachial plexus showed inflammatory changes at that level. A trial with oral valacyclovir followed by intravenous methylprednisolone bolus was administered without further response. However, human intravenous immunoglobulin resulted in complete recovery of the symptoms. CONCLUSIONS: Human immunoglobulin is effective in BP due to zoster infection and must be considered if standard treatment fails. To the best of our knowledge, this is the first report of BP associated to zoster infection successfully treated with intravenous immunoglobulin.


Asunto(s)
Neuropatías del Plexo Braquial/tratamiento farmacológico , Neuropatías del Plexo Braquial/etiología , Encefalitis por Varicela Zóster/complicaciones , Inmunoglobulinas Intravenosas/uso terapéutico , Anciano , Neuropatías del Plexo Braquial/diagnóstico por imagen , Neuropatías del Plexo Braquial/virología , Encefalitis por Varicela Zóster/diagnóstico por imagen , Humanos , Imagen por Resonancia Magnética , Masculino , Conducción Nerviosa/efectos de los fármacos , Enfermedad de Parkinson/complicaciones
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