Vibrio vulnificus infection from tilapia sting wounds in an inland city: A case report.

Vibrio vulnificus is a pathogen that can cause serious and fatal infections, primarily associated with a history of contact with the sea or aquatic organisms or products. However, with global climate change and increased global seafood trade, V. vulnificus infections are also occurring in non-coastal areas. In this report, we present the successful diagnosis and treatment of a case of necrotizing wound caused by V. vulnificus infection in an inland city in southwest China. In addition, we review the epidemiology and distribution of V. vulnificus in China and related vaccine research, which may provide a reference for the clinical diagnosis and treatment of V. vulnificus infection.

Regioselectivity Switch of α-Amino Acid-Derived Esters and MBH Carbonates for the Synthesis of Allyl-Substituted Azlactones.

Allylic azlactones are greatly significant in terms of potential bioactivities and synthetic applications. Owing to the burgeoning interest of the pharmaceutical industry in α-amino acid derivatives, discovering strategies for the synthesis of allylic azlactones is important. Herein, we establish a transition-metal-free regioselectivity switch of α-amino acid-derived esters and MBH carbonates, which exhibits broad reaction scope and good reaction yields. Control reactions indicate that both base and solvent are important for regioselectivity.

Preparation and Characteristics of Building Dust Suppressants with Strong Resistance to Harsh Environments.

Most dust suppressants used for buildings currently lack sufficient resistance to harsh conditions, such as high temperatures and wind erosion. To solve this problem, it is necessary to develop a new type of dust suppressant. In this study, the guar gum molecule was chemically modified to remove the active hydroxyl group in order to significantly improve the stability and adhesion of guar gum. Eventually, a composite dust suppressant was synthesized by incorporating a surfactant and an absorbent agent into modified guar gum. The functional groups of the reaction products were analyzed via infrared experiments, thus confirming the success of the modification. Wind erosion resistance and scanning electron microscopy experiments confirmed the improved bonding capabilities of the composite dust suppressant with dust particles. In experiments on wind erosion resistance, the dust fixation rate exceeded 50% after the application of the composite dust suppressant. The results of the thermogravimetric tests showed that the maximum mass loss rate of the samples with modified guar gum dust suppressants was 6.0% and 28% lower than those of the samples with unmodified guar gum dust suppressants and water, respectively. Furthermore, the tests conducted on pH value and corrosion resistance indicated that the pH value of this dust suppressant was comparable to that of tap water and demonstrated a similar rate of metal corrosion. The practical significance of this study is to improve the dust suppressant used in buildings, to improve the performance of dust suppressant and resistance to harsh environment, and to help to continuously improve the health of personnel and environmental protection during construction. The practical significance of this study is to improve the dust suppressant used in buildings, to improve the performance of dust suppressant and resistance to harsh environments, and to help to continuously improve the health of personnel and environmental protection during construction, which has positive practical significance for the building industry and related fields.

Highly Active Manganese Oxide from Electrolytic Manganese Anode Slime for Efficient Removal of Antibiotics Induced by Dissociation of Peroxymonosulfate.

In this paper, high-activity manganese oxide was prepared from electrolytic manganese anode slime to realize the efficient removal of antibiotics. The effects of sulfuric acid concentration, ethanol dosage, liquid-solid ratio, leaching temperature and leaching time on the leaching of manganese from electrolytic manganese anode slime were systematically studied. Under the optimal conditions, the leaching rate of manganese reached 88.74%. In addition, a Mn3O4 catalyst was synthesized and used to activate hydrogen persulfate (PMS) to degrade tetracycline hydrochloride (TCH). The synthesized Mn3O4 was characterized by XRD, XPS, Raman, SEM and HRTEM. As a result, the prepared Mn3O4 is spherical, with high purity and crystallinity. The catalytic activity of Mn3O4 for PMS to degrade TCH was increased to 82.11%. In addition, after four cycles, the performance remained at 78.5%, showing excellent stability and recyclability. In addition, O2- and 1O2 are the main active species in the degradation reaction. The activity of Mn3O4 is attributed to it containing Mn(II) and Mn(III) at the same time, which can quickly realize the transformation of high-valence and low-valence manganese, promote the transfer of electrons and realize the degradation of organic pollutants.

A clinical case and a review of Mycobacterium fortuitum infections direct diagnosis approach and treatment in a patient with leg fractures.

Mycobacterium fortuitum infections of the musculoskeletal system are commonly missed, given their rarity and the absence of systemic symptoms. In this study, we isolated the M. fortuitum from the skin sinus tract of a traffic accident patient's right medial knee surgical incision (over the open fracture wound), and confirmed by Morphological analysis, MALDI-TOF MS, 16S rRNA gene sequencing, and mNGS. Then we adjusted the treatment plan and treated the patient with cefoxitin, amikacin, and doxycycline. At three months follow-up review, his wound had completely healed. This report may provide a reference for the clinical treatment of Mycobacterium fortuitum infection in patients with open fractures.

Nanoscale magnetic imaging of ferritins in a single cell.

The in situ measurement of the distribution of biomolecules inside a cell is one of the important goals in life science. Among various imaging techniques, magnetic imaging (MI) based on the nitrogen-vacancy (NV) center in diamond provides a powerful tool for the biomolecular research, while the nanometer-scale MI of intracellular proteins remains a challenge. Here, we use ferritin as a demonstration to realize the MI of endogenous proteins in a single cell using the NV center as the sensor. With the scanning, intracellular ferritins are imaged with a spatial resolution of ca. 10 nm, and ferritin-containing organelles are colocalized by correlative MI and electron microscopy. The approach paves the way for nanoscale MI of intracellular proteins.

Decoherence Control of Nitrogen-Vacancy Centers.

Quantum mechanical systems lose coherence through interacting with external environments-a process known as decoherence. Although decoherence is detrimental for most of the tasks in quantum information processing, a substantial degree of decoherence is crucial for boosting the efficiency of quantum processes, for example, in quantum biology and other open systems. The key to the success in simulating those open quantum systems is therefore the ability of controlling decoherence, instead of eliminating it. Motivated by simulating quantum open systems with Nitrogen-Vacancy centers, which has become an increasingly important platform for quantum information processing tasks, we developed a new set of steering pulse sequences for controlling various coherence times of Nitrogen-Vacancy centers; our method is based on a hybrid approach that exploits ingredients in both digital and analog quantum simulations to dynamically couple or decouple the system with the physical environment. Our numerical simulations, based on experimentally-feasible parameters, indicate that decoherence of Nitrogen-Vacancy centers can be controlled externally to a very large extend.