Impact of malocclusion and oral habits on oral health-related quality of life and sleep disturbance in young adults : A cross-sectional study.

PURPOSE: The aim of this study was to investigate the impact of malocclusion and oral habits on oral health-related quality of life and sleep disturbance in young adults. METHODS: A cross-sectional study was conducted with a sample of 213 young adults aged 18-30 years. Dental occlusion data were assessed through clinical examination. A questionnaire was used to collect data on oral habits. Outcomes were collected using the Oral Health Impact Profile (OHIP-14) and Mini Sleep Questionnaire. RESULTS: Anterior open bite (adjusted odds ratio [OR] = 2.41, 95% confidence interval [CI] = 1.02-5.67, p = 0.044), swallowing disorders (adjusted OR = 2.39, 95% CI = 1.13-5.05, p = 0.022), and sleeping on hands were associated with a negative impact on oral health-related quality of life. Females (adjusted OR = 2.61, 95% CI = 1.10-6.17, p = 0.029), teeth grinding (adjusted OR = 2.78, 95% CI = 1.08-7.14, p = 0.034), biting lips or cheeks (adjusted OR = 4.28, 95% CI = 1.49-12.29, p = 0.007), and self-perception of need for orthodontic treatment (adjusted OR = 7.88, 95% CI = 2.12-29.30, p = 0.002) were associated as a risk for sleep disturbances. CONCLUSION: The findings suggest that oral habits and some types of malocclusions can impact oral health-related quality of life. In addition, sleep disturbances were associated with a greater need for orthodontic treatment and a habit of grinding teeth in young adults.

Molecular characterization and frequency of human pegivirus type 1 (HPgV-1) in kidney transplant recipients from Central-West Brazil.

Human Pegivirus Type 1 (HPgV-1), a ubiquitous commensal virus, has been recently suggested as a marker of immunologic function. There is scarce data for the presence, genotypes, and molecular characteristics of HPgV-1 among kidney transplant recipients. Therefore, the objective of this study was to examine the prevalence and the molecular characteristics (cycle threshold, genotypes) of this viral infection among kidney transplant recipients from the Brasília, Federal District of Brazil. HPgV-1 RNA detection in the plasma was assessed by RT-qPCR. Positive samples were submitted to sequencing and phylogenetic analysis of the 5´-UTR portion of the viral genome. The estimated HPgV-1 prevalence among renal-transplant recipients was 20%. The performed phylogenetic inference revealed that the most frequent genotype among these patients was HPgV-1 genotype 2 (78.9%) presented by its two subgenotypes (2 A and 2B), followed by genotypes 1 and 3 (10.5% each). This study presents new data about the HPgV-1 circulation and molecular characteristics among kidney transplant recipients from the Federal District of Brazil. Further work is fundamental to examine the effect of HPgV-1 among patients with immunological suppression, including kidney transplant recipients.

Influence of Neonatal Ankyloglossia on exclusive breastfeeding in the six first months of life: a cohort study. / Influência da Anquiloglossia neonatal na amamentação exclusiva nos seis primeiros meses de vida: estudo de coorte.

PURPOSE: To analyze the influence of ankyloglossia on the prevalence and duration of exclusive breastfeeding of full-term infants up to the sixth month of life. METHODS: Prospective cohort study, carried out with 225 mother-infant dyads who were followed up in the first six months of life in a center specialized in breastfeeding in a tertiary hospital. Full-term infants with asymptomatic ankyloglossia (no need for surgery) were compared with infants without change at monthly follow-up. Ankyloglossia was diagnosed using the Bristol Tongue Assessment Tool, with a positive diagnosis being considered for those with a score less than or equal to 5 considering functional and anatomical aspects. Statistical analyzes were performed using descriptive statistics, logistic regression (weaning determinants), relative risk, and survival curves (to analyze breastfeeding duration between groups with and without ankyloglossia). RESULTS: Ankyloglossia was associated with weaning (considered even partial) before the sixth month of life. After adjusted analysis, a higher risk of weaning was detected in infants with this alteration, with a risk present from the second month of life. In the survival analysis, the duration of breastfeeding in infants with ankyloglossia was shorter when compared to children without alterations. CONCLUSION: Compared to infants with normal lingual frenulum, babies with ankyloglossia had shorter exclusive breastfeeding time, but well above the average observed in the general population. The risk of weaning for this group was also higher.

OBJETIVO: Analisar a influência da anquiloglossia na prevalência e no tempo de exclusividade do aleitamento materno de lactentes a termo até o sexto mês de vida. MÉTODOS: Estudo de coorte prospectivo, realizado com 225 díades mãe-bebê que foram acompanhadas nos seis primeiros meses de vida em centro especializado em amamentação em um hospital terciário. Lactentes a termo com anquiloglossia do tipo assintomática (sem necessidade de cirurgia) foram comparados com lactentes sem alteração em um acompanhamento mensal. O diagnóstico de anquiloglossia foi realizado através do Bristol Tongue Assessment Tool, sendo considerados com diagnóstico positivo aqueles com escore menores ou iguais a 5 considerando os aspectos funcionais e anatômicos. As análises estatísticas foram realizadas através de estatística descritiva, regressão logística (determinantes do desmame), risco relativo e curvas de sobrevivência (para analisar o tempo de aleitamento entre os grupos com e sem anquiloglossia). RESULTADOS: A anquiloglossia esteve associada com o desmame (considerado ainda que parcial) antes do sexto mês de vida. Após análise ajustada, foi detectado maior risco de desmame nos lactentes com a alteração presente, com risco presente a partir do segundo mês de vida. Na análise de sobrevida, o tempo de aleitamento nos lactentes com anquiloglossia foi menor quando comparadas às crianças sem alteração. CONCLUSÃO: Em comparação com lactentes com freio lingual normal, os bebês com anquiloglossia apresentaram tempo menor de aleitamento exclusivo, porém bem acima da média observada na população geral. O risco de desmame para este grupo também foi maior.

Ecological modeling, biogeography, and phenotypic analyses setting the tiger cats' hyperdimensional niches reveal a new species.

Recently, the tiger-cat species complex was split into Leopardus tigrinus and Leopardus guttulus, along with other proposed schemes. We performed a detailed analysis integrating ecological modeling, biogeography, and phenotype of the four originally recognized subspecies-tigrinus, oncilla, pardinoides, guttulus-and presented a new multidimensional niche depiction of the species. Species distribution models used > 1400 records from museums and photographs, all checked for species accuracy. Morphological data were obtained from institutional/personal archives. Spotting patterns were established by integrating museum and photographic/camera-trap records. Principal component analysis showed three clearly distinct groups, with the Central American specimens (oncilla) clustering entirely within those of the Andes, namely the pardinoides group of the cloud forests of the southern Central-American and Andean mountain chains (clouded tiger-cat); the tigrinus group of the savannas of the Guiana Shield and central/northeastern Brazil (savanna tiger-cat); and the guttulus group in the lowland forests of the Atlantic Forest domain (Atlantic Forest tiger-cat). This scheme is supported by recent genetic analyses. All species displayed different spotting patterns, with some significant differences in body measurements/proportions. The new distribution presented alarming reductions from the historic range of - 50.4% to - 68.2%. This multidimensional approach revealed a new species of the elusive and threatened tiger-cat complex.

O ensino de lutas/artes marciais como uma prática de educação libertadora: entremeando círculos de cultura, situações-problema e jogos / The teaching of fights/martial arts as a liberating education practice: interspersing crop circles, situational issues, and games / La enseñanza de lucha/artes marciales como práctica de educación liberadora: intercalando círculos en las cosechas, problemas situacionales y juegos

RESUMO A inserção das Lutas/Artes Marciais no campo escolar tem sido tema frequente no campo da Educação Física. As obras de Paulo Freire emergem como possibilidade para atuação pedagógica nesse tema. Realizou-se uma pesquisa-formação qualitativa, com observação, análise e reflexão sobre a experiência com três turmas de Ensino Médio de uma escola pública do município de Lavras (Brasil), somando-se 44 horas/aula. Recorreu-se a um diário de bordo para registro. Os resultados apontaram para uma vasta bagagem cultural dos estudantes sobre o assunto. Concluiu-se que o ensino de práticas como essa, numa perspectiva de educação libertadora, pode contribuir com a formação de sujeitos autônomos, com visões ampliadas de mundo.

ABSTRACT The insertion of Fights/Martial Arts in the school field has been a frequent theme in the field of Physical Education. Paulo Freire's works emerge as a possibility for pedagogical action in this theme. A qualitative research was carried out, with observation, analysis and reflection on the experience with three high school classes from a public school in the municipality of Lavras (Brazil), adding up to 44 hours/class. A logbook was used for recording. The results pointed to a vast cultural baggage of students on the subject. It was concluded that the teaching of practices like this, in a perspective of liberating education, can contribute to the formation of autonomous subjects, with expanded views of the world.

RESUMEN La inserción de las Luchas/Artes Marciales en el ámbito escolar ha sido un tema frecuente en el campo de la Educación Física. Las obras de Paulo Freire emergen como una posibilidad de acción pedagógica en esta temática. Se realizó una investigación cualitativa, con observación, análisis y reflexión sobre la experiencia con tres clases de secundaria de una escuela pública del municipio de Lavras (Brasil), sumando 44 horas/clase. Para el registro se utilizó un cuaderno de bitácora. Los resultados apuntaron a un vasto bagaje cultural de los estudiantes sobre el tema. Se concluyó que la enseñanza de prácticas como ésta, en una perspectiva de educación liberadora, puede contribuir a la formación de sujetos autónomos, con visiones ampliadas del mundo.

Ankyloglossia severity in infants: maternal pain, self-efficacy, and functional aspects of breastfeeding / Gravidade da anquiloglossia em bebês: dor materna, autoeficácia e aspectos funcionais do aleitamento materno

ABSTRACT Objective: To analyze functional aspects of breastfeeding, self-efficacy, and pain reported by mothers during breastfeeding, in newborns with severe and mild ankyloglossia. Methods: This is an observational study, carried out with 81 babies with ankyloglossia, assessed by the Bristol Tongue Assessment Tool (severe: scores 0-3; mild: scores 4-6) nested in a cohort carried out at the University Hospital of the Federal University of Maranhão, São Luis, Brazil. The functional aspects of breastfeeding were analyzed using the Breastfeeding Observation Form of the United Nations Children's Fund (BOF-UNICEF) and the LATCH Scoring System. Breastfeeding self-efficacy was measured using the Breastfeeding Self-Efficacy Scale — Short-Form. Pain indicators were evaluated by the Short-Form McGill Pain Questionnaire. The significance level adopted was 5%. Results: Maternal age was 26.7±0.8 years, and 64.2% reported high school education. Most babies were male (67.9%), and the birth weight was 3232±60g. A significant association was detected in the sucking aspect evaluated by the BOF-UNICEF [β=0.22 (95%CI 0.07; 0.73), p-value=0.013]. However, the groups did not differ in the assessment of breastfeeding performed by the LATCH scale. The groups had no differences in the assessment of breastfeeding self-efficacy reported by mothers, and in pain scores. Conclusions: Despite the observation of sucking difficulty in infants with severe ankyloglossia., the quality of breastfeeding in general, maternal pain, and self-efficacy reported by mothers do not differ when compared with infants with mild ankyloglossia. Therefore, the severity of ankyloglossia seems not to affect the breastfeeding indicators.

RESUMO Objetivo: Analisar aspectos funcionais da amamentação, autoeficácia e dor relatada pelas mães durante a amamentação, em recém-nascidos com anquiloglossia grave e leve. Métodos: Estudo observacional, realizado com 81 bebês diagnosticados com anquiloglossia avaliados pelo Bristol Tongue Assessment Tool (grave: escores 0-3; leve: escores: 4-6), aninhados em um estudo de coorte realizado no Hospital Universitário da Universidade Federal do Maranhão, São Luís, Brasil. Os aspectos funcionais do aleitamento materno foram analisados por meio do Formulário de Observação da Amamentação do Fundo Internacional para a Infância das Nações Unidas (BOF-UNICEF) e da Escala LATCH. Aautoeficácia foi mensurada por meio da Breastfeeding Self-Efficacy Scale — Short-Form. Os indicadores de dor foram avaliados pelo Short-Form McGill Pain Questionnaire. O nível de significância adotado foi de 5%. Resultados: A idade materna foi 26,7±0,8 anos, e 64,2% concluíram o ensino médio. A maioria dos recém-nascidos era do sexo masculino (67,9%), e o peso ao nascer foi 3232±60g. Foi detectada associação significante no aspecto da sucção avaliado pelo BOF-UNICEF [β=0,22 (IC95% 0,07; 0,73), p=0,013]. No entanto, os grupos não diferiram na avaliação do aleitamento materno realizada pela escala LATCH. Os grupos não apresentaram diferenças na avaliação da autoeficácia em amamentar relatada pelas mães e no escore de dor. Conclusões: Apesar de ter sido observada dificuldade de sucção em lactentes com anquiloglossia grave, a qualidade da amamentação em geral, a dor materna e a autoeficácia relatada pelas mães não diferem quando comparadas com as de lactentes com anquiloglossia leve. Assim, a gravidade da anquiloglossia parece não afetar os indicadores de amamentação.

Influência da Anquiloglossia neonatal na amamentação exclusiva nos seis primeiros meses de vida: estudo de coorte / Influence of Neonatal Ankyloglossia on exclusive breastfeeding in the six first months of life: a cohort study

RESUMO Objetivo Analisar a influência da anquiloglossia na prevalência e no tempo de exclusividade do aleitamento materno de lactentes a termo até o sexto mês de vida. Métodos Estudo de coorte prospectivo, realizado com 225 díades mãe-bebê que foram acompanhadas nos seis primeiros meses de vida em centro especializado em amamentação em um hospital terciário. Lactentes a termo com anquiloglossia do tipo assintomática (sem necessidade de cirurgia) foram comparados com lactentes sem alteração em um acompanhamento mensal. O diagnóstico de anquiloglossia foi realizado através do Bristol Tongue Assessment Tool, sendo considerados com diagnóstico positivo aqueles com escore menores ou iguais a 5 considerando os aspectos funcionais e anatômicos. As análises estatísticas foram realizadas através de estatística descritiva, regressão logística (determinantes do desmame), risco relativo e curvas de sobrevivência (para analisar o tempo de aleitamento entre os grupos com e sem anquiloglossia). Resultados A anquiloglossia esteve associada com o desmame (considerado ainda que parcial) antes do sexto mês de vida. Após análise ajustada, foi detectado maior risco de desmame nos lactentes com a alteração presente, com risco presente a partir do segundo mês de vida. Na análise de sobrevida, o tempo de aleitamento nos lactentes com anquiloglossia foi menor quando comparadas às crianças sem alteração. Conclusão Em comparação com lactentes com freio lingual normal, os bebês com anquiloglossia apresentaram tempo menor de aleitamento exclusivo, porém bem acima da média observada na população geral. O risco de desmame para este grupo também foi maior.

ABSTRACT Purpose To analyze the influence of ankyloglossia on the prevalence and duration of exclusive breastfeeding of full-term infants up to the sixth month of life. Methods Prospective cohort study, carried out with 225 mother-infant dyads who were followed up in the first six months of life in a center specialized in breastfeeding in a tertiary hospital. Full-term infants with asymptomatic ankyloglossia (no need for surgery) were compared with infants without change at monthly follow-up. Ankyloglossia was diagnosed using the Bristol Tongue Assessment Tool, with a positive diagnosis being considered for those with a score less than or equal to 5 considering functional and anatomical aspects. Statistical analyzes were performed using descriptive statistics, logistic regression (weaning determinants), relative risk, and survival curves (to analyze breastfeeding duration between groups with and without ankyloglossia). Results Ankyloglossia was associated with weaning (considered even partial) before the sixth month of life. After adjusted analysis, a higher risk of weaning was detected in infants with this alteration, with a risk present from the second month of life. In the survival analysis, the duration of breastfeeding in infants with ankyloglossia was shorter when compared to children without alterations. Conclusion Compared to infants with normal lingual frenulum, babies with ankyloglossia had shorter exclusive breastfeeding time, but well above the average observed in the general population. The risk of weaning for this group was also higher.

Clonal complexes of carbapenem-resistant Klebsiella pneumoniae recovered from community sewage.

Carbapenem-resistant Klebsiella pneumoniae (CR-Kp) are life-threatening multidrug-resistant bacteria. In this study, CR-Kp strains isolated from sewage treatment plants (STPs) (n = 12) were tested for carbapenemase genes (blaKPC, blaNDM, blaIMP, blaVIM and blaOXA-48) and had their sequence types (ST) and clonal complexes (CCs) defined. A collection of clinical CR-Kp strains recovered in local hospitals was added to phylogenetic analyses along with sewage strains in order to infer clonality among CR-Kp strains. A total of 154 CR-Kp strains were isolated from raw sewage [55.8% (86/154)], treated sewage [25.3% (39/154)] and from water body downstream from STPs [18.8% (29/154)]. No CR-Kp strain was isolated from upstream water samples. blaKPC or blaNDM were detected in 143 (92.8%) strains. The occurrence of blaKPC-or-NDM CR-Kp strains was positively associated with the number of hospitalized patients in the areas serviced by STPs. Eleven STs were detected in CR-Kp strains, most of them belonging to the clinically relevant CC11 [ST11 (n = 13-28.2%) and ST340 (n = 7-15.2%)]. CCs 11, 15, 17, 147 and 2703 are shared by clinical and sewage CR-Kp strains. In conclusion, sewage harbors clinically relevant clones of CR-Kp that resist sewage treatments, contaminating water bodies downstream from STPs.

Torcida ganha jogo? Possíveis efeitos da Covid-19 na vantagem em casa nas séries A e B do Campeonato Brasileiro de Futebol / Crowd wins game? Possible effects of Covid-19 on home advantage in Serie A and B of Brazilian Football Championship / Multitud gana el juego? Posibles efectos del Covid-19 en ventaja de casa en la Serie A y B del Campeonato Brasileño de Fútbol

Introdução: Este trabalho analisa os possíveis desdobramentos advindos da pandemia de Covid-19 para o desempenho esportivo das equipes do Campeonato Brasileiro Séries A e B. Tal abordagem se justifica, pois poderá contribuir para um possível alargamento sobre o tema Vantagem em Casa no futebol brasileiro. Objetivo: comparar o desempenho das equipes mandantes no Campeonato Brasileiro, séries A e B, nos anos em que a pandemia obrigou as equipes a jogarem sem a presença de torcida nos estádios (2020 e 2021), com o desempenho de duas temporadas sem as restrições da pandemia (2019 e 2022). Metodologia: Para isto, foi realizada uma pesquisa documental, com foco na porcentagem de pontos conquistados em casa pelas equipes participantes do Campeonato Brasileiro série A e B nos anos de 2019, 2020, 2021 e 2022. Resultados e discussão: A análise dos dados ocorreu via plataforma Transfermarkt, para calcular o percentual de aproveitamento e evidenciou-se que a variável torcida, isoladamente, não exerceu influência significativa no desempenho das equipes mandantes da Série A e Série B do Campeonato Brasileiro. Conclusão: constatamos que possivelmente, as outras variáveis da Vantagem em Casa conseguiram compensar a ausência de público nos estádios.

Introduction: This work analyzes the possible consequences arising from the Covid-19 pandemic for the sporting performance of teams in the Brazilian Championship Series A and B. Such an approach is justified, as it could contribute to a possible expansion of the theme of Home Advantage in Brazilian football . Objective: to compare the performance of the home teams in the Brazilian Championship, series A and B, in the years in which the pandemic forced teams to play without fans in the stadiums (2020 and 2021), with the performance of two seasons without restrictions of the pandemic (2019 and 2022). Methodology: For this, documentary research was carried out, focusing on the percentage of points won at home by the teams participating in the Brazilian Championship series A and B in the years 2019, 2020, 2021 and 2022. Results and discussion: Data analysis took place via the Transfermarkt platform, to calculate the percentage of success and it was evident that the fan variable, in isolation, did not have a significant influence on the performance of the home teams in Series A and Series B of the Brazilian Championship. Conclusion: we found that the other Home Advantage variables possibly managed to compensate for the absence of an audience.

Introducción: Este trabajo analiza las posibles consecuencias derivadas de la pandemia de Covid-19 para el desempeño deportivo de los equipos del Campeonato Brasileño Serie A y B. Tal enfoque se justifica, ya que podría contribuir para una posible ampliación del tema de la Ventaja de Local. en el fútbol brasileño. Objetivo: comparar el desempeño de los equipos locales en el Campeonato Brasileño, series A y B, en los años en que la pandemia obligó a los equipos a jugar sin aficionados en los estadios (2020 y 2021), con el desempeño de dos temporadas sin restricciones. de la pandemia (2019 y 2022). Metodología: Para ello, se realizó una investigación documental, centrándose en el porcentaje de puntos ganados en casa por los equipos participantes del Campeonato Brasileño de las series A y B en los años 2019, 2020, 2021 y 2022. Resultados y discusión: Se tomó el análisis de los datos. realizado a través de la plataforma Transfermarkt, para calcular el porcentaje de éxito y se evidenció que la variable afición, de forma aislada, no tuvo influencia significativa en el desempeño de los equipos locales en la Serie A y Serie B del Campeonato Brasileño. Conclusión: encontramos que las otras variables Home Advantage posiblemente lograron compensar la ausencia de audiencia.

Does neonatal ankyloglossia interfere in the growth of infants during the first 6 months of life? A case series nested in a cohort study.

BACKGROUND: Ankyloglossia is commonly reported as one of the major causes of breastfeeding difficulty. There is a lack of research on infant growth and latching performance with clinical measures. CASES PRESENTATION: We describe a series of eight clinical cases (three female and five male infants) in a specialized breastfeeding center in a tertiary hospital in Northeast Brazil. The mothers were of mixed race and ranged from 13 to 41 years of age. Ankyloglossia was diagnosed within the first 48 hours after delivery. We measured the standards of growth, the mothers' perception of breastfeeding, and a pain indicator, and performed an assessment of breastfeeding. The regularity of breastfeeding was maintained despite the early diagnosis of ankyloglossia. Growth indicators were not affected in the sixth month in any of the babies, with only one measuring below expectations in the third month, with no impact on general health. CONCLUSIONS: In the cases reported in this paper, the infants overcame the initial difficulties in breastfeeding and maintained their normal growth course in the first 6 months of life.

Environmental spreading of clinically relevant carbapenem-resistant gram-negative bacilli: the occurrence of blaKPC-or-NDM strains relates to local hospital activities.

BACKGROUND: Aquatic matrices impacted by sewage may shelter carbapenem-resistant (CR) Gram-negative bacilli (GNB) harboring resistance genes of public health concern. In this study, sewage treatment plants (STPs) servicing well-defined catchment areas were surveyed for the presence of CR-GNB bearing carbapenemase genes (blaKPC or blaNDM). RESULTS: A total of 325 CR-GNB were recovered from raw (RS) and treated (TS) sewage samples as well as from water body spots upstream (UW) and downstream (DW) from STPs. Klebsiella-Enterobacter (KE) group amounted to 116 isolates (35.7%). CR-KE isolates were recovered from TS, DW (35.7%) and RS samples (44.2%) (p = 0.001); but not from UW samples. KE isolates represented 65.8% of all blaKPC or blaNDM positive strains. The frequency of blaKPC-or-NDM strains was positively associated with the occurrence of district hospitals located near STPs, as well as with the number of hospitalizations and of sewer connections serviced by the STPs. blaKPC-or-NDM strains were recovered from ST samples in 7 out of 14 STPs, including four tertiary-level STPs; and from 6 out of 13 DW spots whose RS samples also had blaKPC-or-NDM strains. CONCLUSIONS: Clinically relevant GNB bearing blaKPC-or-NDM resist sewage treatments and spread into environmental aquatic matrices mainly from STPs impacted by hospital activities.

Alterations of oral functions and dental malocclusions in adolescents: a cross-sectional population-based study.

This article aims to assess whether alterations of oral functions (AOF) are associated with malocclusion (MO)'s type and severity. Cross-sectional study of a representative sample of 332 adolescents aged 12 years in São Luís-MA, Northeastern Brazil. MO criteria included Angle's classification, Dental Aesthetic Index, and other morphological problems. The AOF were evaluated by breathing, phonation, chewing, and swallowing. Odds ratios (OR) and 95% confidence intervals (95%CI) were calculated using logistic and multinomial regression analyses (α=5%). Mouth breathing was associated with defined (OR=3.84; 95%CI=1.45-10.12), disabling (OR=4.34; 95%CI=1.99-9.49), and class III (OR=4.15; 95%CI=1.19-14.54) MO. Phonation problems were associated with defined (OR=2.01; 95%CI=1.02-4.39), disabling (OR=3.04; 95%CI=1.55-5.96), and Class II (OR=2.02; 95%CI=1.28-3.18) MO. Chewing disorders were associated with posterior crossbite (PCB) (OR=2.32; 95%CI=1.12-4.82). Swallowing disorders were associated with Class III MO (OR=5.66; 95%CI=1.35-23.71), PCB (OR=6.13; 95%CI=2.76-13.62), and posterior open bite (OR=4.53; 95%CI=1.72-8.92). Breathing and phonation alterations are associated with MO in anterior arch segments, while chewing and swallowing disorders, in the posterior segments.

Alterations of oral functions and dental malocclusions in adolescents: a cross-sectional population-based study / Alterações das funções orais e má oclusão em adolescentes: um estudo transversal de base populacional

Abstract This article aims to assess whether alterations of oral functions (AOF) are associated with malocclusion (MO)'s type and severity. Cross-sectional study of a representative sample of 332 adolescents aged 12 years in São Luís-MA, Northeastern Brazil. MO criteria included Angle's classification, Dental Aesthetic Index, and other morphological problems. The AOF were evaluated by breathing, phonation, chewing, and swallowing. Odds ratios (OR) and 95% confidence intervals (95%CI) were calculated using logistic and multinomial regression analyses (α=5%). Mouth breathing was associated with defined (OR=3.84; 95%CI=1.45-10.12), disabling (OR=4.34; 95%CI=1.99-9.49), and class III (OR=4.15; 95%CI=1.19-14.54) MO. Phonation problems were associated with defined (OR=2.01; 95%CI=1.02-4.39), disabling (OR=3.04; 95%CI=1.55-5.96), and Class II (OR=2.02; 95%CI=1.28-3.18) MO. Chewing disorders were associated with posterior crossbite (PCB) (OR=2.32; 95%CI=1.12-4.82). Swallowing disorders were associated with Class III MO (OR=5.66; 95%CI=1.35-23.71), PCB (OR=6.13; 95%CI=2.76-13.62), and posterior open bite (OR=4.53; 95%CI=1.72-8.92). Breathing and phonation alterations are associated with MO in anterior arch segments, while chewing and swallowing disorders, in the posterior segments.

Resumo O objetivo deste artigo é avaliar se alterações das funções orais (AFO) estão associadas ao tipo e gravidade da maloclusão (MO). Estudo transversal com amostra representativa de 332 adolescentes de 12 anos em São Luís-MA, Nordeste do Brasil. Critérios de MO incluíram Classificação de Angle, Índice de Estética Dental e outros problemas morfológicos. As AFO foram avaliadas por respiração, fonação, mastigação e deglutição. Odds ratios (OR) e intervalos de confiança de 95% (IC95%) foram calculados em análises de regressão logística e multinomial (α=5%). Respiração oral foi associada com MO definida (OR=3,84; IC95%=1,45-10,12), incapacitante (OR=4,34; IC95%=1,99-9,49) e classe III (OR=4,15; IC95%=1,19-14,54). Problemas de fonação foram associados às MO definidas (OR=2,01; IC95%=1,02-4,39), incapacitantes (OR=3,04; IC95%=1,55-5,96) e Classe II (OR=2,02; IC95%=1,28-3,18). Alterações na mastigação foram associadas à mordida cruzada posterior (MCP) (OR=2,32; IC95%=1,12-4,82). Deglutição atípica foi associada à MO Classe III (OR=5,66; IC95%=1,35-23,71), MCP (OR=6,13; IC95%=2,76-13,62) e mordida aberta posterior (OR=4,53; IC95%=1,72-8,92). Alterações de respiração e fonação estão associadas às MO nos segmentos anteriores do arco, enquanto as de mastigação e deglutição, nos segmentos posteriores.

Orthodontic Movement of Central Incisor with Previously-healed Root Fracture associated with Unerupted Canines.

Teeth with root fracture may need orthodontic treatment. This case report presents the management of unerupted canines in a patient with previously-healed/untreated horizontal root fracture in the maxillary left central incisor. The malocclusion was treated maintaining pulp vitality considering the principles to improve the eruption path of maxillary canines and move short-rooted teeth. The root-fractured tooth remained symptomless after orthodontic treatment without significant adverse effects, and stayed stable following 2-year follow-up.

Insertion sequences disrupting mgrB in carbapenem-resistant Klebsiella pneumoniae strains in Brazil.

OBJECTIVES: This study aimed to characterise insertional mutations disturbing themgrB gene in carbapenem-resistant Klebsiella pneumoniae (CRKp). METHODS: A total of 118 clinical CRKp isolates were surveyed for polymyxin resistance and insertion sequence (IS) elements disruptingmgrB. RESULTS: Of the 118 isolates, 78 (66.1%) displayed polymyxin resistance, of which 54% (42/78) hadmgrB::IS inserts. Sequencing analyses showed 13 insertion sites in mgrB. mgrB::ISSen4(IS3) was observed for the first time in CRKp. CONCLUSIONS: Ten different IS elements disruptedmgrB, with a predominance (76%) of IS5 sequences.

DLLME-SFO-GC-MS procedure for the determination of 10 organochlorine pesticides in water and remediation using magnetite nanoparticles.

There exists a high demand for fast, simple, and reliable methodologies for determining the presence of organochlorine pesticides (OCPs) on environmental samples. Moreover, the toxicity and accumulation of potential OCPs in several environments have led to the development of technologies that achieve their removal from contaminated waters. In this study, a novel method combining a dispersive liquid-liquid microextraction procedure based on the solidification of floating organic drop is developed and validated for the extraction, preconcentration, and determination of 10 OCPs: α-BHC, p,p'-DDE, δ-BHC, dieldrin, p,p'-DDT, endosulfan I, endosulfan sulfate, heptachlor, heptachlor epoxide (isomer B), and methoxychlor in water samples. The results show that the calibration curves were linear for all the studied compounds, and the coefficients of correlation higher than 0.99. The variation coefficient for precision and accuracy was lower than 10%, and the accuracy ranged from 93 to 105%. Low limit of detection and limit of quantification values ranging from 0.06-3.00 ng mL-1 and 0.20-10 ng mL-1 were obtained, respectively. The capability of the proposed method was confirmed using an analysis of the water samples before and after the degradation process; this was achieved by employing nanomaterials, while performing an analysis of 160 real samples that were sourced from a Brazilian river. A cobalt-doped magnetite was applied for the environmental remediation of the studied compounds, and it was verified that the novel material has the potential to be used in environmental remediation with a degradation efficiency exceeding 80% for the majority of the studied compounds.