RESUMEN
OBJECTIVE: To assess the association between atopic dermatitis (AD) and ascariasis in 2 to 10-aged children from the neighborhood Pedregal, in the city of Campina Grande, Brazil, an area of low socioeconomic index. METHODS: Cross-sectional study conducted with the use of the standard questionnaire from the International Study of Asthma and Allergies in Childhood (ISAAC) and stool parasitological exam for Ascaris lumbricoides. The dependent variable was AD diagnosis: absent, mild, and severe. Multivariate logistic regression and descriptive analysis of the variable were used. Associations were estimated using relative risk (RR) and odds ratio (OR). The statistical inference was based on 95% confidence intervals (95%CI). RESULTS: We assessed 1,195 children, 612 (51.2%) female. The AD prevalence was 24.6%, and ascariasis prevalence was 26.1%. In the mild AD group of children, 44 (36.7%) were infected by A. lumbricoides while in the severe AD group, 40 (22.9%) had the same geohelminthosis (p = 0.01). Comparing negative cases of AD between mild and severe forms, the infection with A. lumbricoides increased the frequency of mild AD (RR = 1.7; p = 0.009), but not the severe form (RR = 0.86; p = 0.46). Evaluating only the positive cases of dermatitis, 120 mild AD (40.8%) and 176 with severe AD (58.2%), it can be said that the exposure to the parasite decreased the frequency of the severe form of dermatitis (RR = 1.46; p = 0.016). CONCLUSION: There is a high prevalence of AD and of ascariasis in the population studied. The severe AD is related to lower parasitemia of A. lumbricoides.
Asunto(s)
Ascariasis/epidemiología , Dermatitis Atópica/epidemiología , Animales , Ascariasis/parasitología , Ascaris lumbricoides/aislamiento & purificación , Brasil/epidemiología , Niño , Preescolar , Dermatitis Atópica/clasificación , Métodos Epidemiológicos , Femenino , Humanos , MasculinoRESUMEN
Objetivo: Avaliar a associação entre dermatite atópica (DA) e ascaridíase em crianças de 2 a 10 anos do bairro do Pedregal, Campina Grande (PB), área de baixos indicadores socioeconômicos. Métodos: Trata-se de estudo transversal a partir da aplicação do questionário padrão do International Study of Asthma and Allergies in Chlidhood (ISAAC) e exame parasitológico de fezes para Ascaris lumbricoides. A variável dependente foi o diagnóstico de DA ausente, DA leve e DA grave. Efetuou-se análise de regressão logística multivariada, bem como análise descritiva das variáveis do estudo. As associações foram estimadas por meio de risco relativo (RR) e razão de chances (odds ratio, OR). A inferência estatística foi baseada em intervalos de confiança de 95 por cento (IC95 por cento). Resultados: Foram avaliadas 1.195 crianças, sendo 51,2 por cento (n = 612) do sexo feminino. A prevalência de DA foi de 24,6 por cento, e a de ascaridíase, de 26,1 por cento. Das crianças com DA leve, 44 (36,7 por cento) eram parasitadas pelo A. lumbricoides, enquanto que 40 (22,9 por cento), com DA grave, apresentavam a mesma geo-helmintose (p = 0,01). Comparando-se os casos negativos para DA com os casos leves e graves, constatou-se que a presença de ascaridíase aumentou a ocorrência de dermatite leve (RR = 1,7; p = 0,009), mas não de DA grave (RR = 0,86; p = 0,46). Avaliando-se apenas os casos positivos de dermatite, DA leve (n = 120; 40,8 por cento) e DA grave (n = 176; 59,2 por cento), verifica-se que a exposição parasitária diminui a ocorrência da forma grave (RR = 1,46; p = 0,016). Conclusão: Existe elevada prevalência de DA e de ascaridíase na população estudada. A forma grave de DA está associada com baixa parasitemia de A. lumbricoides.
Objective: To assess the association between atopic dermatitis (AD) and ascariasis in 2 to 10-aged children from the neighborhood Pedregal, in the city of Campina Grande, Brazil, an area of low socioeconomic index. Methods:Cross-sectional study conducted with the use of the standard questionnaire from the International Study of Asthma and Allergies in Childhood (ISAAC) and stool parasitological exam for Ascaris lumbricoides. The dependent variable was AD diagnosis: absent, mild, and severe. Multivariate logistic regression and descriptive analysis of the variable were used. Associations were estimated using relative risk (RR) and odds ratio (OR). The statistical inference was based on 95 percent confidence intervals (95 percentCI). Results: We assessed 1,195 children, 612 (51.2 percent) female. The AD prevalence was 24.6 percent, and ascariasis prevalence was 26.1 percent. In the mild AD group of children, 44 (36.7 percent) were infected by A. lumbricoides, while in the severe AD group, 40 (22.9 percent) had the same geohelminthosis (p = 0.01). Comparing negative cases of AD between mild and severe forms, the infection with A. lumbricoides increased the frequency of mild AD (RR = 1.7; p = 0.009), but not the severe form (RR = 0.86; p = 0.46). Evaluating only the positive cases of dermatitis, 120 mild AD (40.8 percent) and 176 with severe AD (58.2 percent), it can be said that the exposure to the parasite decreased the frequency of the severe form of dermatitis (RR = 1.46; p = 0.016). Conclusion: There is a high prevalence of AD and of ascariasis in the population studied. The severe AD is related to lower parasitemia of A. lumbricoides.