RESUMEN
There were examined and treated 52 patients with odontogenic phlegmons of maxillofacial region, from them 25 patients received basic therapy and 27 - additionally sodium hypochrorite, rexod and reamberin during 5 days. It was established that combined use of the abovementioned preparations exerted positive influence upon oxidation-reduction processes, promoted tissue hypoxia and endotoxicosis correction.
Asunto(s)
Celulitis (Flemón)/terapia , Radicales Libres/antagonistas & inhibidores , Enfermedades Maxilares/microbiología , Enfermedades Maxilares/terapia , Oxidantes/uso terapéutico , Hipoclorito de Sodio/uso terapéutico , Adolescente , Adulto , Celulitis (Flemón)/tratamiento farmacológico , Técnicas Electroquímicas , Humanos , Persona de Mediana Edad , Oxidación-Reducción , Adulto JovenRESUMEN
The paper shows limitations of the traditional indices used to evaluate a patient's chemical status and describes methods for assessment of its uniformity, by using nonparametric chi 2 test, identifying patient subgroups, and comparing a few groups. A new procedure is proposed to present cytochemical findings.
Asunto(s)
Células Sanguíneas/química , Histocitoquímica/estadística & datos numéricos , Células Sanguíneas/citología , Histocitoquímica/métodos , Humanos , Estadísticas no ParamétricasRESUMEN
The study assesses absolute and relative errors in the calculation of cytochemical indices in a precise patient. At present, the semiquantitative index (the mean cytochemical coefficient (MCC) after G. Astaldi and L. Verg) is widely used to evaluate the cytochemical activity of leukocytes. At the same time other indices, such as differentiating cytochemical coefficient (DCC) after I. G. Bondarenko, occasionally find application. Analysis of the results of simulation of an array containing 500 leukograms has demonstrated that the individual relative detection error for MCC ranges from 13 to 21% and that for DCC 20 to 51%. The results of the study enable an adequate estimation of the ways of expressing the cytochemical findings, which are proposed by different authors.
Asunto(s)
Errores Diagnósticos , Hemocromatosis/diagnóstico , Histocitoquímica/normas , Humanos , Cómputos Matemáticos , Reproducibilidad de los ResultadosRESUMEN
The paper compares the apparent blood viscosity (BV)-shift rate (SR) curves, by using uni- and multidimensional dispersion analysis. The study has indicated that when admitted to hospital, patients with maxillofacial phlegmons have higher BV due to worse blood rheological and coagulative properties. An analysis of the BV-SR curves has shown that there are the most significant differences between the parameters at moderate and high SR while the differences are frequently insignificant at low SR (on admission, on days 3 and 10). For hemocorrection of increased BV, co-administration of disaggregatory agents is indicated during the treatments proposed. Uni- and multidimensional analyses used to examine the curves of the apparent BV to the individual value of SR and throughout its range are the most informative tools for assessing the quality of treatment in patients with maxillofacial phlegmons and a statistically warranted method for multiple comparisons.
Asunto(s)
Transfusión de Sangre Autóloga , Celulitis (Flemón)/terapia , Enfermedades Maxilomandibulares/terapia , Oxidantes/administración & dosificación , Hipoclorito de Sodio/administración & dosificación , Terapia Combinada , Femenino , Humanos , Masculino , Oxidación-ReducciónRESUMEN
Possibilities of modern methods of maths statistics for comparative evaluation of efficacy of different methods of treatment of patients with suppurative-inflammatory diseases of maxillo-facial region were analyzed and an integral index of treatment efficacy was suggested. Application of the integral index of treatment efficacy showed that intravenous injection of sodium hypochlorite and autohemotherapy with oxidized blood led to the closest apposition of cluster center of these patients to the cluster center of healthy persons. It testifies to greater efficacy of such treatment of the disease in comparison to the other methods.
Asunto(s)
Enfermedades Maxilomandibulares/terapia , Infecciones de los Tejidos Blandos/terapia , Adolescente , Adulto , Transfusión de Sangre Autóloga/métodos , Análisis por Conglomerados , Cara , Análisis Factorial , Femenino , Hemostasis , Humanos , Enfermedades Maxilomandibulares/sangre , Enfermedades Maxilomandibulares/patología , Masculino , Persona de Mediana Edad , Oxidantes/administración & dosificación , Hipoclorito de Sodio/administración & dosificación , Infecciones de los Tejidos Blandos/sangre , Infecciones de los Tejidos Blandos/patología , Supuración , Resultado del TratamientoRESUMEN
Twenty-five patients with pyoinflammatory maxillofacial diseases treated in an inpatient setting in the Regional Dentistry Clinic of Krasnodar and 8 healthy volunteers were examined. After opening and draining of the purulent focus the patients were divided into 2 groups. Group 1 consisted of 21 patients treated by intravenous 0.04% sodium hypochlorite (SHC) and intravenous infusions of SHC-oxidized autoblood for 2-3 days. Group 2 (6 pts) was treated by intravenous infusions of SHC-oxidized autoblood for 6 days. The criteria of intoxication were erythrocyte resistance tests in hypotonic sodium chloride and at different concentrations of urea in isotonic medium. A new method for evaluating erythrogram deviations from reference values is proposed, which helps adequately assess the severity of intoxication.