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Comput Biol Med ; 171: 108028, 2024 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-38335817

RESUMEN

Raman Spectroscopy promises the ability to encode in spectral data the significant differences between biological samples belonging to patients affected by a disease and samples of healthy patients (controls). However, the decoding and interpretation of the Raman spectral fingerprint is still a difficult and time-consuming procedure even for domain experts. In this work, we test an end-to-end deep-learning diagnostic pipeline able to classify spectral data from saliva samples. The pipeline has been validated against the SARS-COV-2 Infection and for the screening of neurodegenerative diseases such as Parkinson's and Alzheimer's diseases. The proposed system can be used for the fast prototyping of promising non-invasive, cost and time-efficient diagnostic screening tests.


Asunto(s)
Enfermedad de Alzheimer , COVID-19 , Humanos , Saliva , Aprendizaje Automático , COVID-19/diagnóstico , Prueba de COVID-19
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