1.
Molecules
; 24(21)2019 Oct 25.
Artículo
en Inglés
| MEDLINE
| ID: mdl-31731437
RESUMEN
A catalyst-free heterocyclization reaction of α-chloroglycinates with thiobenzamides or thioureas leading to 2,4-disubstituted-5-acylamino-1,3-thiazoles has been developed. The methodology provides straightforward access to valuable building blocks for pharmaceutically relevant compounds.