Asunto(s)
Queilitis/etiología , Labio/patología , Lupus Eritematoso Discoide/complicaciones , Anciano , Anticuerpos Antinucleares/inmunología , Antirreumáticos/administración & dosificación , Antirreumáticos/uso terapéutico , Queilitis/diagnóstico , Queilitis/tratamiento farmacológico , Femenino , Humanos , Hidroxicloroquina/administración & dosificación , Hidroxicloroquina/uso terapéutico , Lupus Eritematoso Discoide/diagnóstico , Lupus Eritematoso Discoide/tratamiento farmacológico , Lupus Eritematoso Discoide/inmunología , Factor de Protección Solar/métodos , Resultado del TratamientoRESUMEN
Multiple miliary osteoma cutis consists of heterotopic foci of bone tissue in the dermis and subcutaneous tissue. Patients usually present with multiple, asymptomatic facial papules of several millimetres in diameter which cause distress regarding their cosmetic appearance. The condition is described as rare, as only a few cases have been reported since its first description in 1864 by Virchow. We therefore carried out a comprehensive literature search and review, in which 102 published cases were retrieved and analysed. The demographic and clinical aspects, as well as current therapy solutions, of this probably overlooked condition are discussed.
Asunto(s)
Enfermedades Óseas Metabólicas/diagnóstico , Enfermedades Óseas Metabólicas/terapia , Osificación Heterotópica/diagnóstico , Osificación Heterotópica/terapia , Enfermedades Cutáneas Genéticas/diagnóstico , Enfermedades Cutáneas Genéticas/terapia , Conservadores de la Densidad Ósea/uso terapéutico , Enfermedades Óseas Metabólicas/epidemiología , Procedimientos Quirúrgicos Dermatologicos , Diagnóstico Diferencial , Humanos , Osificación Heterotópica/epidemiología , Retinoides/uso terapéutico , Enfermedades Cutáneas Genéticas/epidemiologíaRESUMEN
Debridement is essential for the optimal care of venous leg ulcers. Several debridement methods with different limitations may be deployed. Trichloroacetic acid (TCA) is used for several dermatological purposes. Its application as a chemical debridement method for leg ulcers has never been explored. We designed a prospective study to determine the role of 80% TCA solution as a chemical debridement method for leg ulcers, regarding efficacy and procedure-associated pain. Chronic venous leg ulcers were treated with 3 cycles of 80% TCA solution or curettage over 1 week. Pain and the mean percentage of fibrin and devitalized tissue covering wound bed were evaluated. At the end of the study, a trend towards larger fibrin mean reduction among the TCA treated ulcers was observed, although this difference was not statistically significant (P = .35). The mean pain score after TCA application was significantly reduced compared to pain after curettage alone (P < 0.001). TCA presented several advantages over mechanical debridement: it is a more selective debridement method, has haemostatic properties, and a simpler and faster application. The 80% TCA solution may be a cheap, simple, and considerably less-painful chemical debridement method for venous leg ulcers compared to classical mechanical debridement.