Are premenstrual syndrome and aggression related to body mass index in adolescents?

OBJECTIVE: This cross-sectional study aimed to examine the relationship between premenstrual syndrome (PMS) and aggression during adolescence with body mass index (BMI), which is a topic not yet investigated in the literature. PATIENTS AND METHODS: This cross-sectional study was conducted with 1,450 adolescents aged 12-18 years, who applied to the Pediatric Adolescent Outpatient Clinic and voluntarily agreed to participate in the study. Anthropometric measurements of the adolescents were taken and the Premenstrual Syndrome Scale and Buss-Perry Aggression Questionnaire were administered to the adolescents. It was discovered that all the adolescents participating in the study had PMS. RESULTS: It was determined that as the levels of PMS were elevated, physical aggression, hostility, anger and verbal aggression gradually increased. Additionally, this increase was statistically significant (p<0.001). It was further discovered that there were statistically significant differences between the BMI classifications of the adolescents and PMS, physical aggression, hostility, anger and verbal aggression statuses (p<0.001). Accordingly, it was determined that as the BMI values of the adolescents increased, PMS and aggressive attitude levels increased. CONCLUSIONS: This study is the first in the literature to examine the relationship between PMS and aggression, and BMI in adolescents. Within this framework, it was determined that PMS frequency and aggression levels were high in overweight/obese adolescents. Accordingly, it is predicted that both PMS and aggression levels can decrease with healthy body weight in adolescents.

A DIFFERENT PERSPECTIVE OF ELEVATED LACTATE IN PEDIATRIC PATIENTS WITH DIABETIC KETOACIDOSIS.

OBJECTIVE: This study aims to determine the frequency and prognostic significance of lactic acidosis in children with diabetic ketoacidosis (DKA) admitted to the pediatric intensive care unit. METHODS: The study was carried out retrospectively by examining the patients admitted to the pediatric intensive care unit for the treatment of DKA. The ages of the patients ranged from 2 to 18 years. The patients with the following parameters were enrolled in the study: serum blood glucose>200 mg/dL, ketonuria presence, venous blood gas pH ≤7.1, bicarbonate <15. RESULTS: A total of 56 patients were included in the study with a mean age of 111.07 ± 51.13 months. The recovery time from DKA was 16.05 ± 6.25 h in the group with low lactate level and it was 13.57 ± 8.34 h in the group with high lactate level with no statistically significant difference. There was a negative correlation between lactate levels and the recovery time from DKA. CONCLUSION: Lactic acidosis is common in DKA, and unlike other conditions, such as sepsis, it is not always a finding of poor prognosis that predicts the severity of the disease or mortality. We think that high lactate may even protect against possible brain edema-cerebral damage in DKA.