[THE CHROMATOGRAPHY-MASS SPECTROMETRY ANALYSIS OF MICROBIAL FATTY ACIDS IN HUMAN BIOLOGICAL FLUIDS AND THEIR CLINICAL SIGNIFICANCE].

The technique of mass-spectrometric microbial markers is known for almost 20 years. The technique is described in a number of research publications, dissertations and methodological literature. It passed the registration in Roszdravnadzor and is permitted for implementation as a new medical technology in medical institutions on the territory of the Russian Federation ("The evaluation of microecological human status using technique of mass-spectrometry" license FS No 2010/038 of 24.02.2010). The technique of mass-spectrometric microbial markers began to be developed as instrument of clinical routine analysis and monitoring of microecological status, infection and disbiosises in clinical and out-patient practice. The description of technology of mass- spectrometric microbial markers in this aspect requires different than before approach to introduction of clinical laboratory assistants and physicians into technique application. The substantiation given concerning species specificity of composition of fatty acids and (fatty) aldehydes of cellular wall of microorganisms as a basis of their species differentiation in pure culture. The choice is explained concerning molecular markers for their detection in blood and other clinical material with the purpose of further reconstruction of composition of human microbial cenosis (microecology) on blood or calculation of composition of mixed infection in organs om samples of inflammation focus--urine, liquor, phlegm, exudate, drainage, and similar samples containing chemical information about microbes.

[The functional state of the organism of 8- 16 years old schoolchildren residing in Moscow and Kiev].

An assessment of the functional state of the organism in 2929 Moscow and 2043 Kiev schoolchildren aged 8 - 16 years. It was shown that in terms of main physiometric indices ofphysical development Moscow and Kiev children 8 - 16 years differ from each other There were established statistically significant difference in the force capacities: in Kiev children aged 8 - 9 years muscle strength was significantly higher than that of their peers in Moscow. The force capacities of 10 - 14 year old girls and 16 - year old boys residing in Kiev were acknowledged to be significantly lower than that of in children of the same age residing in Moscow. Respiratory capacities in Kiev schoolchildren in all age and gender groups were significantly lower than in Muscovites of the same age. It was suggested to activate preventive measures aimed at increasing the functional capacities of the cardio-respiratory system, in the first place for the children - residents of Kiev.

[Changes in the physical development of Kiev schoolchildren over a ten-year period (1996-2008)].

Physical development and morphofunctional state were assessed in 2452 urban schoolchildren, by using the Ukrainian standards (intergroup regression scales). During their schooling, the Kiev schoolchildren of both sexes were shown to have significant qualitative and quantitative physical and morphofunctional worsening that was more obvious in boys. Not more than 57-59% of the Kiev children aged 6 to 17 years had normal physical development and harmonic morphofunctional state. Every six Kiev boys and every five girls had overweight and reduced chest circumference. In the period 1996-2008, there was significant weight gain without respective changes in chest circumference and height, which indicated an imbalance in growth processes and physical development in the present-day Kiev schoolchildren. Evaluation standards for schoolchildren's physical development were developed and put into practice of the state sanitary-and-epidemiological service of Ukraine.

[Physical development of schoolchildren in Moscow and Kiev].

Physical development was assessed in 2329 Moscow schoolchildren and 1433 Kiev ones aged 8 to 11 and 15 to 17 years. The Moscow and Kiev children aged 8 to 11 years did not differ in the basic anthropometric indices of physical development and force capacities. Gracilization processes were prevalent in the Kiev schoolchildren. Statistically significant differences were established in respiratory capacities: lung capacity was significantly higher in the Moscow children aged 8 to 10 years than in the Kiev ones of their age. Climatic and geographical features were found in the physical development of the Kiev teenagers: significantly higher chest circumference was observed in 15-16-year-old girls and 15-year-old boys than in the Moscow children of the same age. It is stated that the force capacities of the Kiev teenagers were significantly lower in all age-sex groups than in the Muscovites of the same age. It is proposed to activate preventive measures aimed at enhancing the functional capacities of the cardiorespiratory system primarily in the children living in Kiev.

[The informative value of international standards in evaluating the physical development of Ukrainian schoolchildren].

The physical development of 1347 rural schoolchildren was evaluated by the WHO international (BMI-for-age Z scores) and Ukrainian (intergroup regression scales) standards. Only every two of the children with normal physical development (by the WHO version) had moderate harmonious development. Every 10 "normal" group schoolchildren were stated to have underweight and 2-3% of the children were overweight. Among the 17-year-old girls, underweight was encountered 4 times more frequently than that in the boys of the same age, which confirms social influence on the formation of body proportions in the present-day rural girls. The specific features of physical development and the signs of gracialization processes were established in the pediatric population. Physical development evaluation by the body mass index may be employed in some (pediatric, sportive) branches of medicine, but the results of evaluation by the WHO international standards fail to provide objective knowledge of the status of physical development and its harmonicity as a whole. Intergroup regression scales are proposed to be used to evaluate physical development.

[Computed tomography in the diagnosis of complicated abdominal aortic aneurysms]. / Komp'iuternaia tomografiia v diagnostike oslozhnennykh anevrizm briushnoi polosti.

The paper analyzes the results of computed tomography (CT) conducted in 54 patients with complicated abdominal aortic aneurysms (AAA). Of them, 37 cases were diagnosed as having a complete rupture. There was dissection of the wall of the aneurysmally altered aorta and its slight tear in 11 and 6 cases, respectively. CT has been shown to allow one to diagnose complications due to AAA, their pattern, and site, to identify the factors that increase a risk for rupture, such as a slight tear of the inner layers of the wall of the aneurysmal abdominal aorta and its wall dissection. This all assists in solving a variety of the problems associated with treatment policy and may substantially reduce postoperative morbidity in this group of patients.

[Characteristics of actual nutrition and health of children in regions of the Russian Federation]. / Kharakteristika fakticheskogo pitaniia i zdorov'ia detei v regionakh Rossiiskoi Federatsii.

In the article the problems of actual nutrition and state of Russian children health are considered. The carried out examinations of the vitaminous status have shown presence of a deficit of vitamins E, B1, B6, PP, and also calcium, phosphorus, iron lactate, zinc in daily ration of children. The inadequate organization of C-vitaminization of boiled food in children establishments, low supplying of learning schools by a hot food, insufficient use of products from suer milk, fish, juices, meat products, butter, vegetables, fruit, eggs in a nutrition of children is marked. In same of regions of Russia the inadequate nutrition organization of early age children is marked. The positive experience of areas (St.-Petersburg, Ul'yanovsk, Rostov, Smolensk, Kirov, Kurgan, Samara region, Republic Buryatiya) on organization of children and juveniles nutrition, development of the regional programs on a children's food industry evolution, on providing of early age children by food stuffs, on improvement of a schoolboys nutrition, on improvement a nutrition of children in children's preschool establishments is analyzed. The positive experience of nutrition organization of children on an example of the Ryazan and Arkhangel'sk regions surveyed. The actual information about a vitaminization, quality and safety of children's nutrition, ready dishes in the organized collectives on data of 1999 are given.

[Computed tomography in refined diagnosis of abdominal aortic aneurysm: comparison of radiation therapies versus surgical outcomes and morphological studies of resected abdominal aortic fragments]. / Komp'iuternaia tomografiia v utochnennoi diagnostike anevrizm briushnoi aorty (po materialam sopostavleniia luchevykh metodov i rezul'tatov khirurgicheskogo i morfologicheskogo issledovanii rezetsirovannykh fragmentov briushnoi aorty).

The results of computed tomography (CT) was compared with ultrasonographic and angiographic findings in 168 patients. All data of radiation diagnosis of abdominal aortic aneurysms (AAA) were compared with those of operations and morphological studies of the resected fragments of the aortic parts changed due to aneurysms. These comparisons provided a detailed characterization of the potentialities of CT performed on a third-generation unit in the presurgical diagnosis of this abnormality. At the same time, detailed XCT findings (semeiotics of AAA and their complications, such infiltration, dissection, and rupture) are given. The study shows benefits of the refined AAA by applying routine CT. The paper gives a diagnostic algorithm of using radiation studies (ultrasonography, CT, angiography) in the diagnosis of AAA. Third-generation CT units widely used in clinical practice are shown to provide necessary and complete information on the magnitude of AAA. This makes it possible to extend the capacities of timely detection of this abnormality and to make a successful surgical intervention.

[The physical development, health status and "school maturity" of 6-year-old children (based on data from Shatura, Moscow Province)]. / Fizicheskoe razvitie, sostoianie zdorov'ia i "shkol'naia zrelost'" detei 6-letnego vozrasta (po materialam Shatury Moskovskoi oblasti).

The health status was studied in 223 preschool children from a kindergarten in the town of Shatura, Moscow Region. All the children were divided into groups according to their health status and physical development. The proportion of children unready to go to school was 32.2%.