1.
Chembiochem
; 14(17): 2259-62, 2013 Nov 25.
Artículo
en Inglés
| MEDLINE
| ID: mdl-24166757
RESUMEN
Chemical diversity: Two SAM-dependent N-methyltransferases-LmbJ from the biosynthesis of the antibiotic lincomycin and CcbJ from celesticetin biosynthesis-have been characterized and compared. Both tested enzymes form multimers and are able to utilize N-demethyllincomycin, the natural substrate of LmbJ, with comparable efficiency.