ChatGPT and dentistry: a step toward the future.

This article aims to explore the integration of ChatGPT, an advanced conversational artificial intelligence model, in the field of dentistry. The review primarily consists of information related to the capabilities and functionalities of ChatGPT and how these abilities can aid dental professionals. This study includes data from research papers, case studies, and relevant literature on language models, as well as papers on dentistry, patient communication, dental education, and clinical decision-making. A systematic approach was used to select relevant studies and literature. The selection criteria focused on papers that specifically discussed the integration of language models, ChatGPT in particular, in dentistry and their applications. The study findings revealed that ChatGPT has significant potential to revolutionize dentistry by offering various applications and benefits. It can enhance patient engagement and understanding through personalized oral health information and guidance. In dental education, ChatGPT can provide interactive learning, case studies, and virtual patient simulations. ChatGPT can also assist researchers in analyzing dental literature, identifying patterns, and generating insights. Moreover, it supports dentists with evidence-based recommendations, treatment options, and diagnostic support. Integrating ChatGPT in dentistry can be highly beneficial, but it is crucial to address ethical considerations, accuracy, and privacy concerns. Responsible implementation and continuous improvement of its functionalities are necessary to ensure that patient care and outcomes are improved.

Pyodermatitis-pyostomatitis vegetans: a case report and systematic review focusing on oral involvement.

BACKGROUND: Pyodermatitis-pyostomatitis vegetans (PPV) is a rare mucocutaneous disease characterized by multiple pustules and it is considered a marker for inflammatory bowel disease (IBD). The oral manifestations of this condition are referred to as pyostomatitis vegetans (PSV). PURPOSE: To investigate which features could help in establishing the diagnosis of PSV, with or without cutaneous lesions, based on information retrieved from all cases of PSV described in the literature. A case of PV from the authors was also included in the analysis. METHODS: An electronic search was undertaken, last updated in August 2022. Inclusion criteria included publications reporting cases of PSV, with the diagnosis confirmed by the pathological examination of oral or skin lesions, and presence of IBD. RESULTS/CONCLUSIONS: Sixty-two publications with 77 cases of PSV and an associated IBD were included. Features that are helpful in establishing the diagnosis of PSV are snail track appearance of oral lesions, an associated IBD (which is not always symptomatic), evidence of intraepithelial clefting on microscopic examination of oral lesions, and peripheral blood eosinophilia. A gold standard for the management of PSV does not exist and high-level evidence is limited. There is no established therapeutic protocol for PSV and management primarily consists of topical and/or systemic corticosteroids, antirheumatic drugs (sulfasalazine, mesalazine), monoclonal antibody (infliximab, adalimumab) immunosuppressives (azathioprine, methotrexate), antibiotics (dapsone), or a combination of these. The risk of recurrence of oral lesions is considerable when the medication dose is decreased or fully interrupted.

Oral squamous cell carcinoma arising from areas of Graft-versus-host disease: A systematic review / Carcinoma oral de células escamosas que surge de áreas de enfermedad de injerto contra huésped: una revisión sistemática

Background: Graft-versus-host disease (GVHD) is an immune system reaction that occurs in patients with ahistory of hematopoietic stem cell transplantation (HSCT), in which the grafted donor's cells attack those of thehost. The objective of this systematic review was to present a study on oral squamous cell carcinoma (OSSC) thatdeveloped from GVHD areas in patients undergoing HSCT.Material and Methods: An electronic search was conducted in the databases PUBMED, WEB OF SCIENCE,SCOPUS, MEDLINE and SCIENCE DIRECT, according to PRISMA guidelines. Results: Of the 1582 results, 23 articles were included, resulting in 81 cases. The most common underlying diseasefor performing the transplant was Myeloid Leukemia (55.6%). The mean age was 39 years, with a predilection formales (64.2%). The tongue was the site of GVHD that most frequently underwent transformation to SCC (59.3%).The average time between transplantation and the development of GVHD was of approximately of 8 months, whilethe average period of development between transplantation and the development of OSCC was of approximately of111 months. The most common treatment to GVHD was cyclosporine associated with corticosteroids.Conclusions: OSCCs arising from areas of GVHD present a different evolution from conventional oral carcinomas,since they affect younger patients, smoking and alcohol are not important etiological factors and finally because theypresent good prognosis, but further studies with larger number cases followed are needed to confirm our findings.(AU)

Oral manifestations of amyloidosis and the diagnostic applicability of oral tissue biopsy.

BACKGROUND: Amyloidosis exhibits a variable spectrum of systemic signs and oral manifestations that can be difficult to diagnose. This study aimed to characterize the clinical, demographic, and microscopic features of amyloidosis in the oral cavity. METHODS: This collaborative study involved three Brazilian oral pathology centers and described cases with a confirmed diagnosis of amyloidosis on available oral tissue biopsies. Clinical data were obtained from medical records. H&E, Congo-red, and immunohistochemically stained slides were analyzed. RESULTS: Twenty-six oral biopsies from 23 individuals (65.2% males; mean age: 59.6 years) were included. Oral involvement was the first sign of the disease in 67.0% of cases. Two patients had no clinical manifestation in the oral mucosa, although the histological analysis confirmed amyloid deposition. Amyloid deposits were distributed in perivascular (88.0%), periacinar and periductal (80.0%), perineurial (80.0%), endoneurial (33.3%), perimuscular (88.2%), intramuscular (94.1%), and subepithelial (35.3%) sites as well as around fat cells (100.0%). Mild/moderate inflammation was found in 65.4% of cases and 23.1% had giant cells. CONCLUSIONS: Amyloid deposits were consistently found in oral tissues, exhibiting distinct deposition patterns. Oral biopsy is less invasive than internal organ biopsy and enables the reliable identification of amyloid deposits even in the absence of oral manifestations. These findings corroborate the relevance of oral biopsy for the diagnosis of amyloidosis.

Contribution of public oral pathology services to the diagnosis of oral and oropharyngeal cancer in Brazil.

This study aimed to evaluate the contribution of oral and maxillofacial pathology laboratories (OMPLs) in Brazilian public universities to the diagnosis of lip, oral cavity, and oropharyngeal squamous cell carcinoma (SCC). A cross-sectional study was performed using biopsy records from a consortium of sixteen public OMPLs from all regions of Brazil (North, Northeast, Central-West, Southeast, and South). Clinical and demographic data of patients diagnosed with lip, oral cavity, and oropharyngeal SCC between 2010 and 2019 were collected from the patients' histopathological records. Of the 120,010 oral and maxillofacial biopsies (2010-2019), 6.9% (8,321 cases) were diagnosed as lip (0.8%, 951 cases), oral cavity (4.9%, 5,971 cases), and oropharyngeal (1.2%, 1,399 cases) SCCs. Most cases were from Brazil's Southeast (64.5%), where six of the OMPLs analyzed are located. The predominant profile of patients with lip and oral cavity SCC was Caucasian men, with a mean age over 60 years, low schooling level, and a previous history of heavy tobacco consumption. In the oropharyngeal group, the majority were non-Caucasian men, with a mean age under 60 years, had a low education level, and were former/current tobacco and alcohol users. According to data from the Brazilian National Cancer Institute, approximately 9.9% of the total lip, oral cavity, and oropharyngeal SCCs reported over the last decade in Brazil may have been diagnosed at the OMPLs included in the current study. Therefore, this data confirms the contribution of public OMPLs with respect to the important diagnostic support they provide to the oral healthcare services extended by the Brazilian Public Health System.

Gingival neoplasms: a multicenter collaborative study of 888 patients in Brazil

Background: To evaluate the prevalence and clinicopathological features of a large series of gingival neoplasms in Brazil. Material and methods: All gingival benign and malignant neoplasms were retrieved from the records of six Oral Pathology Services in Brazil, during a 41-year period. Clinical and demographic data, clinical diagnosis, and histopathological data were collected from the patients' clinical charts. For statistical analysis, the chi-square, median test of independent samples and the U Mann-Whitney tests were used, considering a significance of 5%. Results: From 100,026 oral lesions, 888 (0.9%) were gingival neoplasms. There were 496 (55.9%) males, with a mean age of 54.2 years. Most cases (70.3%) were malignant neoplasms. Nodules (46.2%) and ulcers (38.9%) were the most common clinical appearance for benign and malignant neoplasms, respectively. Squamous cell carcinoma (55.6%) was the most common gingival neoplasm, followed by squamous cell papilloma (19.6%). In 69 (11.1%) malignant neoplasms, the lesions were clinically considered to be inflammatory or of infectious origin. Malignant neoplasms were more common in older men, appeared with larger size, and with a time of complaint shorter than benign neoplasms (p<0.001). Conclusions: Benign and malignant tumors may appear as nodules in gingival tissue. In addition, malignant neoplasms, especially squamous cell carcinoma, should be considered in the differential diagnosis of persistent single gingival ulcers. (AU)

Oral follicular lymphoma: a clinicopathologic and molecular study.

Follicular lymphoma is a hematolymphoid neoplasm that originates from germinal center B cells. It is made up of a combination of small cleaved centrocytes and a varying quantity of larger non-cleaved centroblasts to describe the clinical, microscopic, immunohistochemical, and molecular features of oral follicular lymphomas. Follicular lymphomas affecting the oral cavity were retrieved from pathology files. Immunohistochemistry was performed to confirm the diagnosis, and fluorescence in situ hybridization (FISH) was employed to detect rearrangements in BCL2, BCL6, and MYC genes. Clinical and follow-up data were obtained from the patient's medical and pathology files. Twenty cases were obtained. There was an equal sex distribution (10 males: 10 females) and a mean age of 60.9 years (range: 10-83 years-old). Lesions presented as asymptomatic swellings, usually in the palate (10 cases) and the buccal mucosa (7 cases). Five patients presented with concomitant nodal involvement. Microscopic evaluation depicted the follicular growth pattern with diffuse areas in six cases. Grades 1 and 2 follicular lymphomas represented 12 cases, while grade 3A neoplasms accounted for other 8 cases. Two cases showed rearrangements in MYC, BCL2, and BCL6 genes, while single BCL2 translocation was found in eight cases. Two cases had no translocation. Three patients deceased and the 2-year overall survival achieved 88%. Follicular lymphoma affecting the oral cavity is uncommon, usually affects the palate as a non-ulcerated swelling and the presence of a systemic disease most always be ruled out.

Acinic cell carcinoma of the oral and maxillofacial region: an international multicenter study

Abstract The aim of this study was to describe the prevalence, clinicopathological, and prognostic features of acinic cell carcinoma (AciCC) of the oral and maxillofacial region. AciCC cases were retrospectively retrieved from 11 pathology centers of three different countries. Medical records were examined to extract demographic, clinical, pathologic, and follow-up information. A total of 75 cases were included. Females (65.33%) with a mean age of 45.51 years were mostly affected. The lesions usually presented as an asymptomatic (64.28%) nodule (95.66%) in the parotid gland (70.68%). The association of two histopathological patterns was the most common finding (48.93%) and the tumors presented mainly conventional histopathological grades (86.11%). Surgical treatment was performed in the majority of the cases (59.19%). Local recurrence was observed in 20% of the informed cases, regional metastasis in 30.43%, and distant metastasis in 12.50%. The statistical analysis showed that the cases with a solid histopathological pattern (p=0.01), high-grade transformation (p=0.008), recurrence (p=0.007), and regional metastasis (p=0.03) were associated with poor survival. In conclusion, high histopathological transformation, presence of nodal metastasis, and recurrence were prognostic factors for AciCC of the oral and maxillofacial region.

Synchronous jawbone diseases: a multicenter retrospective study

Abstract The aim of this study is to report an original case series of synchronous jawbone diseases. Data of patients seen over 13 years were extracted from the files of three Oral Radiology and Pathology diagnostic centers in Brazil. The clinical, radiographic, and laboratory characteristics were tabulated and analyzed by the authors; the patients were described according to lesion type. Seventy-two synchronous jawbone diseases were included in this study. Florid osseous dysplasia, Gorlin-Goltz syndrome, and cherubism were the most frequent disorders reported in this case series. In addition, the posterior mandible area was the main site of manifestation. Florid osseous dysplasia and Gorlin-Goltz syndrome represented two-thirds of our samples. With the utilization of adequate demographic, clinical, and radiologic information, it is possible to diagnose most of the synchronous lesions of jawbones. Sometimes, however, we need complementary exams, such as histopathologic and biochemical analysis or dosing of calcium, phosphorus, and alkaline phosphatase.

Contribution of public oral pathology services to the diagnosis of oral and oropharyngeal cancer in Brazil

Abstract This study aimed to evaluate the contribution of oral and maxillofacial pathology laboratories (OMPLs) in Brazilian public universities to the diagnosis of lip, oral cavity, and oropharyngeal squamous cell carcinoma (SCC). A cross-sectional study was performed using biopsy records from a consortium of sixteen public OMPLs from all regions of Brazil (North, Northeast, Central-West, Southeast, and South). Clinical and demographic data of patients diagnosed with lip, oral cavity, and oropharyngeal SCC between 2010 and 2019 were collected from the patients' histopathological records. Of the 120,010 oral and maxillofacial biopsies (2010-2019), 6.9% (8,321 cases) were diagnosed as lip (0.8%, 951 cases), oral cavity (4.9%, 5,971 cases), and oropharyngeal (1.2%, 1,399 cases) SCCs. Most cases were from Brazil's Southeast (64.5%), where six of the OMPLs analyzed are located. The predominant profile of patients with lip and oral cavity SCC was Caucasian men, with a mean age over 60 years, low schooling level, and a previous history of heavy tobacco consumption. In the oropharyngeal group, the majority were non-Caucasian men, with a mean age under 60 years, had a low education level, and were former/current tobacco and alcohol users. According to data from the Brazilian National Cancer Institute, approximately 9.9% of the total lip, oral cavity, and oropharyngeal SCCs reported over the last decade in Brazil may have been diagnosed at the OMPLs included in the current study. Therefore, this data confirms the contribution of public OMPLs with respect to the important diagnostic support they provide to the oral healthcare services extended by the Brazilian Public Health System.

Sialolithiasis of the submandibular gland associated with stafne bone defect: case report / Sialolitíase da glândula submandibular associada a defeito ósseo de stafne: relato de caso

ABSTRACT Sialolithiasis is the formation of calcific concretions within duct of a salivary gland that affects the submandibular gland with greater prevalence. Stafne bone cavity is a rare mandibular defect of unknown etiology, which commonly presents glandular tissue inside. The aim of this work is to report the first clinical case of sialolithiasis of the submandibular gland with associated Stafne bone defect. Although most of Stafne bone cavity are associated with the salivary gland, there are no studies that prove the association between the two injuries, and further studies are needed to elucidate the relationship between the injuries.

RESUMO A sialolitíase é a formação de cálculos no interior do ducto de uma glândula salivar que acomete com maior prevalência a glândula submandibular. O defeito ósseo de Stafne é um defeito mandibular raro de etiologia desconhecida, que comumente apresenta tecido glandular no interior. O objetivo desse trabalho é relatar o primeiro caso clínico de sialolitíase da glândula submandibular com defeito ósseo de Stafne associado.Apesar da maioria dos desfeitos ósseos de Stafne estarem associado à glândula salivar, não há estudos que comprovem a associação entre as duas lesões, sendo necessários mais estudos para elucidar a relação entre as lesões.

Uso do guia endodôntico para resolução de canais calcificados: relato de caso / Use of endodontic guide for resolution of calcified root canals: case report

Introdução: a ciência endodôntica tem como objetivo a manutenção do elemento dentário em função no sistema estomatognático, por meio de procedimentos de sanificação, modelagem e obturação dos condutos radiculares. Porém, o sucesso do tratamento pode estar comprometido devido à presença de obliterações parciais ou totais da cavidade pulpar, que dificultam ou, até mesmo, impedem o procedimento. Recentemente, os avanços tecnológicos possibilitaram a transposição dessas barreiras com a confecção de um guia que permite o acesso retilíneo e direciona ao forame apical do canal obliterado. Métodos: o presente estudo descreve o uso do guia endodôntico em um paciente do sexo masculino, de 54 anos de idade, diagnosticado com necrose pulpar no elemento #14, com obliteração do conduto palatino. Resultados: o sucesso do tratamento pôde ser observado após seis meses de controle radiográfico e ausência de sintomatologia. Conclusões: o tratamento endodôntico de canais calcificados por meio da Endodontia guiada demonstrou ser uma abordagem clinicamente viável para localizar canais radiculares obliterados e prevenir acidentes e complicações nos dentes que não podem ser acessados de forma previsível por meio da terapia endodôntica tradicional (AU).

Introduction: Endodontic science aims to maintain the dental element in function in the stomatognathic system, through procedures of sanification, modeling and obturation of the root conduits. However, the success of the treatment may be compromised due to the presence of partial or total obliterations of the pulp cavity, which hinder and even impede the procedure. Recently, the technological advance made it possible to transpose these barriers with the creation of a guide that allows rectilinear access and directs to the apical foramen of the obliterated canal. Methods: The present study describes the use of the endodontic guide in a 54-year-old male patient, diagnosed with pulp necrosis in element 14, with obliteration of the palatine conduit. Results: The success of the treatment could be observed after six months of radiographic control and absence of symptomatology. Conclusions: Endodontic treatment of calcified canals through guided endodontics demonstrates a clinically viable approach to locate obliterated root canals and prevent accidents and complications in teeth that cannot be predictably accessed through traditional endodontic therapy (AU).

Linicopathological analysis of head and neck rhabdomyosarcoma: A series of 10 cases and literature review

Background: To describe the clinicopathological characteristics of a series of head and neck rhabdomyosarcoma (RMS) and to review the literature. Material and Methods: Cases diagnosed as RMS affecting the head and neck region were retrospectively retrieved from the files of two Brazilian institutions from January 2006 to January 2017. Data on clinical features (sex, age and affected site), microscopic subtype, immunohistochemical results, treatment employed and follow-up status were obtained from the patient's medical charts. Results: During the period considered, 10 cases of RMS were identified. Females predominated (4M:6F), the mean age at diagnosis was 16.5 years-old and the orbit was the most affected site (4 cases). Microscopically, most cases were classified as embryonal RMS (6 cases) and the Desmin/Myogenin/Myo-D1 immunohistochemical positivity was useful to confirm the diagnosis. Chemotherapy and radiotherapy were applied to 9 and 8 patients respectively, whereas 2 patients were treated by surgery. Recurrences occurred in 3 patients and distant metastasis in 2 cases. Nine patients were alive in their last follow-up, 3 of them with disease, whereas 1 patient died due to the disease. Conclusions: Head and neck RMS is an aggressive malignant neoplasm which demands especial concern to achieve early diagnosis and successful treatment (AU)

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Nuclear metallothionein in oral squamous cell carcinoma: clinicopathological parameters and patient survival

Abstract The aim of this study was to identify the immunoexpression of methallothionein in oral squamous cell carcinoma as well as to address the correlation with clinical features, histological grade and patient survival. Samples were collected from 93 patients with tongue squamous cell carcinoma who presented for follow-up. Immunohistochemical expression of methallothionein in all groups was performed. The scoring system has previously been published by Tsurutani in 2005, which is based on intensity and distribution of staining. We used Kappa index to evaluate the degree of observers' agreement under metallothionein immunostaining and histological grade. Associations between methallothionein expression and clinical parameters (age, gender, smoking, tumor size, lymph node metastasis and disease stage) were examined for statistical significance using the chi-squared test. The overall survival rates were estimated by the Kaplan-Meier method and the relationship between protein expression and survival was compared using the log-rank test (p < 0.05). Our results showed no statistically significant association between methallothionein immunostaining and the selected clinicopathological variables. Immunohistochemistry results showed positive nuclear immunostaining for metallothionein in 62,37% (58/93) and negative for metallothionein 37,63% (35/93). The degree of examiners agreement by Kappa varied from substantial to perfect and both metallothionein immunostaining and histological grade were explored. The present study suggests that positive methallothionein expression found in tongue squamous cell carcinoma may not help to predict survival in the analyzed samples, as well as no relation between the protein and histological grade and clinical features was observed. In conclusion, the present study suggests that metallothionein is not associated with tongue squamous cell carcinoma clinicopathological characteristics and aggressiveness.

Criação de uma rede de proteção contra o carcinoma epidermóide em estágio avançado no Estado do Pará / Creation of a protection network against advanced squamous cell carcinoma in the State of Pará

Este projeto buscou capacitar um grupo de cirurgiões-dentistas de todas as Regionais de Saúde do Estado do Pará para identificar e biopsiar lesões potencialmente malignas e malignas de boca. Além disso, buscou -se preparar os cirurgiões-dentistas para remoção dos focos de infecção da boca, evitando os casos de osteoradionecrose naqueles pacientes que serão submetidos à radioterapia. No primeiro momento, professores da Universidade Federal do Pará do Curso de Odontologia e Preceptores da Residência em Cirurgia e Traumatologia Buco-Maxilo-Facial do Hospital Universitário João de Barros Barreto (HUJBB) foram aos municípios sedes das 12 Regionais de Saúde do interior do Estado para proferir palestras sobre os aspectos clínicos e de imagem das lesões potencialmente malignas e malignas da cavidade oral, assim como ensinamentos teóricos sobre técnicas de biópsias e sobre a patogênese da osteoradionecrose. Posteriormente, dois cirurgiões-dentistas de cada Regional de Saúde foram receberam treinamento prático no Serviço de Diagnóstico em Patologia Oral do HUJBB, em Belém do Pará. Acreditamos que atividades similares possam diminuir os altos índices de pacientes que chegam a Belém com cânceres de boca em estágios avançados, e consequentemente aumentar a sobrevida dos pacientes, além de diminuir os custos do tratamento dos pacientes acometidos carcinoma epidermóide de boca no Estado do Pará. Adicionalmente, foi realizado o mapeamento das regiões de maior incidência de lesões malignas de boca no Estado do Pará, o que permitirá a intensificação de medidas de prevenção nessas micro-regiões.

Ki-67 protein predicts survival in oral squamous carcinoma cells: an immunohistochemical study

Abstract The aim of this study was to identify the expression of Ki-67 and MCM3 in oral squamous cell carcinoma (OSCC) as well as to address the correlation with patient survival and clinical features. Samples were collected from 51 patients with OSCC who presented for follow-up. Immunohistochemical expression of Ki-67 and MCM3 in all groups was performed. The scoring system was previous published by Tsurutani in 2005. We used Kappa index to evaluate observers agreement degree. The associations between protein expression and clinical variables were examined for statistical significance using the chi-squared test. The overall survival rates were estimated by the Kaplan-Meier method and the relationship between protein expression and survival was compared using the log-rank test (p < 0.05). The overall survival time for a patient with positive immunostaining for Ki-67 is shorter than for a patient with negative immunostaining, (log-rank test, p = 0.00882). Patients with tumor size T3 and T4 showed a statistically significant relationship with Ki-67 immunoexpression (log-rank test, p = 0.0174). The relationship between Ki-67 expression and the relation between age, gender, smoking, tumor site, lymph node metastasis and disease stage was not significant. The examiners agreement degree by Kappa presented p value < 0.05. There was not a significant correlation when we evaluated MCM3 expression regarding clinical characteristics and survival rate. From these results, the present study suggests that positive Ki-67 expression found in OSCC patients may contribute to predict the survival in OSCC samples, as well as the relation between the protein and the tumor size.

Tratamento cirúrgico de ameloblastoma sólido convencional: relato de caso clínico

O ameloblastoma convencional é uma neoplasia benigna originada do tecido epitelial odontogênico encontrado nos ossos maxilares. É caracterizado, clinicamente, como tumor de crescimento lento, na maioria dos casos, é assintomático ou pode causar parestesias, assim como pode ocasionar deslocamento, mobilidade e reabsorção dental. Histologicamente, a variante multicística possui diversos padrões, como: folicular, plexiforme e desmoplásico. Devido a essas variações histo -patológicas, existem diversos métodos de tratamento, desde a enucleação e curetagem até ressecções mais agressivas. Sendo que essas são bem mais indicadas, tendo em vista o potencial agressivo e infiltrativo da lesão. Objetivo: este trabalho visa relatar um caso clínico de ameloblastoma multicístico tratado por ressecção marginal mandibular. Relato de caso: paciente do gênero feminino, 40 anos de idade, com hipótese diagnóstica de ameloblastoma por meio de radiografia panorâmica de rotina. Por intermédio da biópsia incisional, foi diagnosticado ameloblastoma multicístico em região de corpo, ângulo e ramo mandibular esquerdo. O tratamento de escolha foi, assim como na maioria dos casos relatados na literatura, a ressecção cirúrgica. Considerações finais: essa opção de tratamento é mais justificada pelo alto índice de recidiva das lesões tratadas de forma mais conservadora. No presente trabalho, a paciente foi mantida em proservação por trinta meses, período em que não foi observado nenhum sinal de recidiva da lesão ou complicações pós-operatórias.

Linfangioma microcístico em língua: relato de caso / Microcystic Lymphangioma of the Tongue: Case Report

Linfangiomas são malformações hamartomatosas dos vasos linfáticos, raras, benignas, congênitas e de etiologia desconhecida. Tratam-se de proliferações benignas que envolvem o sistema linfático tendo uma predileção pela cabeça, pescoço e cavidade oral. Há um prognóstico bom em relação às lesões em língua na maioria dos casos, exceto quando lesões volumosas podem comprometer as vias aéreas. O objetivo deste estudo é relatar um caso clínico de linfangioma localizado na língua, bem como revisar a literatura pertinente enfocando os aspectos clínicos e possibilidades terapêuticas... (AU)

Lymphangiomas are hamartomatous malformations of the lymphatic vessels, rare, benign, congenital and of unknown etiology. These are benign proliferations involving the lymphatic system having a predilection for the head, neck and oral cavity. There is a good prognosis in relation to injuries to the tongue in most cases, except when bulky lesions may compromise the airway. The objective of this study is to report a case of lymphangioma located on the tongue, as well as review the literature focusing on the clinical and therapeutic possibilities... (AU)

Tumor odontogênico adenomatoide folicular em maxila: relato de caso / Follicular adenomatoid odontogenic tumor in maxilla: case report

Tumor odontogênico adenomatoide (TOA) é uma lesão benigna incomum de origem odontogênica, caracterizado pelo crescimento lento, progressivo, indolor, de consistência firme, cujo tamanho, normalmente não atinge grandes proporções. Há predileção pela região anterior de maxila e o envolvimento de um dente impactado; geralmente o canino, é recorrente, caracterizando a variante folicular. O TOA apresenta três variantes: folicular, extrafolicular e periférica, que não se distinguem microscopicamente, porém são diferenciadas com achados clínicos ou imaginológicos. O presente trabalho descreve um caso de tumor odontogênico adenomatoide folicular, presente em maxila tratado por enucleação e curetagem. O paciente encontra-se em acompanhamento pós-cirúrgico de 30 meses, sem quaisquer sinais clínicos e radiográficos de recidivas da lesão... (AU)

Adenomatoid odontogenic tumor (AOT) is an uncommon benign lesion of odontogenic origin, characterized by slow growth, progressive painless, firm consistency, with size that normally does not reach large proportions. There is a predilection for the anterior maxilla and the involvement of an impacted tooth, usually the canine, is recurrent, featuring follicular variant. The TOA have three variants: follicular, extrafollicular and peripheral, which are not distinguishable microscopically, but clinically or imaging. This paperdescribes a case of follicular adenomatoid odontogenic tumor present in the maxilla, treated by enucleation and curettage with 30 months follow-up without clinical and radiographic signs of injury recurrence... (AU)

Tratamento cirúrgico de granuloma central de células gigantes agressivo em maxila com Acesso Weber Ferguson: relato de caso / Surgical treatment of aggressive central giant cell granuloma on the jaw using the Weber Ferguson Approach: a case report

O Granuloma central de células gigantes (GCCG) é uma entidade não neoplásica, tendo em vista suas características clínicas e imaginológicas faz-se a definição do padrão da lesão em agressiva ou não-agressiva que irá determinar o tratamento de escolha, quando agressiva causa destruição óssea considerável. O presente trabalho visa relatar um caso clínico de Granuloma Central de Células Gigantes agressiva em maxila com tratamento cirúrgico de enucleação com acesso cirúrgico de Weber Ferguson, atualmente esse paciente encontra-se com dezoito meses de acompanhamento sem sinais de recidiva... (AU)

Central giant cell granuloma is a non-neoplastic entity in which the clinical and imaging characterisitics identify the injury as an aggressive or nonaggressive lesion, a distinction that will determine the choice of treatment, bearing in mind that the aggressive form may cause significant bone destruction. This paper describes a case of aggressive central giant cell granuloma in the maxilla treated surgically using the Weber Ferguson approach. After eighteen months of follow-up the patient shows no signs of recurrence... (AU)