1.
Acta Crystallogr C
; 55 ( Pt 3): 413-6, 1999 Mar 15.
Artículo
en Inglés
| MEDLINE
| ID: mdl-10220870
RESUMEN
The structures of two absorption furosemide prodrugs, hexanoyloxymethyl 4-chloro-N-furfuryl-5-sulfamoyl-anthranilate (C19H23CIN2O7S), (I), and benzoyloxymethyl 4-chloro-N-furfuryl-5-sulfamoylanthranilate (C20H17CIN2O7S), (II), are described in this paper and compared with furosemide and four other prodrugs. The molecular conformations of both compounds are similar to those of the other prodrugs; the packing and the crystal system are the primary differences. Compound (I) crystallizes in the trigonal space group R3 and compound (II) in the monoclinic space group P2(1)/n. The packing of both structures is stabilized by a three-dimensional hydrogen-bond network.
Asunto(s)
Cristalografía por Rayos X , Furosemida/farmacocinética , Absorción Intestinal , Profármacos/farmacocinética , Enlace de Hidrógeno , Modelos Moleculares
2.
Odontología Uruguaya
; 35(2): 36-44,
Artículo
| URUGUAIODONTO
| ID: odn-42375
3.
Odontol. urug
; 35(1): 36-44, 1985. tab
Artículo
en Español
| LILACS
| ID: lil-51675