False positive finding on whole-body iodine-131 scan secondary to contaminated face mask: an uncommon peril in current COVID pandemic.

Covid-19 has changed the practice of present-day medicine. Social-distancing, hand-sanitation and use of face-mask are important measures taken against its spread. Post-thyroidectomy whole-body diagnostic I-131 scan is an important preliminary investigation for risk stratification and further management in thyroid cancer. False positive findings on diagnostic scan are not uncommon and must be evaluated to avoid unnecessary work-up and treatment. Clinical and biochemical correlation with adjunct SPCET/CT imaging may differentiate true from false-positive lesions. We report a case of unusual false positive linear neck tracer on whole-body diagnostic I-131 scan due to the use of an I-131 contaminated face mask.

Radioactive Iodine Uptake in Postoperative Seroma: A Cause for False Positivity.

Besides the known physiologic uptake of 131I, the literature describes various false-positive findings on 131I scans in benign lesions, inflammation, traumatic sites, and postsurgical sites, to name a few. However, to the best of our knowledge, no study has shown false-positive uptake of 131I in a postoperative seroma at the postsurgical site. We describe such a case here.

Posttraumatic Scab on 131I Whole-Body Scan-A False-Positive Finding.

ABSTRACT: 131I scan plays a crucial role in the management of patients with differentiated thyroid cancer for the evaluation of remnant thyroid tissue, residual/recurrent metastatic disease, posttherapy tracer distribution, and response assessment to high-dose 131I therapy. Different causes secondary to physiological, pathological, and anatomical variations have been described for false-positive findings in the whole-body planar images. This case report of a patient of differentiated thyroid cancer with undocumented trauma to the left knee region a day before receiving the high-dose radioiodine therapy showed an interesting image finding of tracer uptake at unusual site in the posttherapy whole-body 131I scan.

Revisiting 99mTc-MIBI Radioguided Surgery in Management of TENIS Syndrome.

Management of patients with thyroglobulin elevated and negative iodine scan is still a challenge with limited options left as the disease stops concentrating iodine. The minimally invasive surgery is the best option for residual/recurrent locoregional disease in postsurgical setup requiring accurate presurgical localization. Intraoperative gamma probe using low-dose tracer has shown its utility in radioguided surgery. The authors present a 46-year-old man with thyroglobulin elevated and negative iodine scan showing FDG-avid left supraclavicular lymph node on whole-body F-FDG PET/CT with physiological uptake on whole-body radioactive iodine scan, where Tc-MIBI radioguided probe helped in carrying out minimally invasive surgery with excision of malignant node.