[Necrotizing sialometaplasia. The clinico-pathological analysis of 6 cases]. / La sialometaplasia necrotizzante. Analisi clinico-patologica di 6 casi.

The clinical and histopathological findings of 6 cases of necrotizing sialometaplasia (NS) are discussed and compared with the literature. The authors report 4 cases of NS of the minor salivary glands and 2 cases with associated tumor of the parotid gland and describe age, sex, site, clinical presentations, prognosis, etiopathogenesis and histological features of NS. Analysis of the data shows the difficulty of a differential diagnosis of NS of the minor salivary glands with other ulcero-erosive diseases of the oral cavity with traumatic, neoplastic or inflammatory origin.

[Adenolymphoma of the salivary glands. The anatomicoclinical, epidemiological and therapeutic aspects of 76 cases]. / Adenolinfoma della ghiandole salivari. Aspetti anatomo-clinici, epidemiologici e terapeutici di 76 casi.

A series of 76 cases of adenolymphoma (Warthin's tumor) of the salivary glands is presented with emphasis on its epidemiological, clinico-pathological and therapeutic features; together with the analysis of the clinical records and of the epidemiological data, this study has reevaluated the histopathological features of the 76 cases of Warthin's tumor on hematoxylin-eosin stained slides. On these bases, the authors underline the frequent multifocality and/or bilaterality of Warthin's tumor (11.3% of cases), its frequent association with tumors of other sites (11.3% of cases), the prevalence in males (M:F ratio = 24:1) and in adults (mean age: 57 years) of this type of tumor. Furthermore, this study confirms the parotid gland as the elective site for Warthin's tumor and the possibility to categorize this entity into four different histological types. The latter finding should be kept in mind especially when fine needle aspiration (FNA) is used as a preoperative diagnostic procedure for Warthin's tumor to avoid misleading diagnosis and overtreatment. From the analysis of the results the authors underline the need for a complex and multidisciplinary approach to the diagnosis of Warthin's tumor in order to allow conservative surgery with preservation of the facial nerve.

[Bilateral adenolymphoma (Warthin's tumor) of the parotid. The anatomicoclinical, diagnostic and therapeutic aspects of 2 cases]. / L'adenolinfoma (tumore di Warthin) bilaterale della parotide. Aspetti anatomo-clinici, diagnostici e terapeutici di due casi.

Cystadenoma lymphomatosum or Warthin's tumor of the parotid glands appears bilateral in 8-10% of cases, synchronous (rarely), metachronous (frequently) and sometimes with multicentric aspects. After the review of the epidemiological, pathogenetic, clinical, radiographic and histologic data, the authors present two cases of bilateral Warthin's tumor, metachronous (7 years), nodular-isolated in the first one and metachronous (5 years), nodular-multicentric in the second one. The patients after CAT scan and NMR examinations, and a fine needle aspiration biopsy were treated with superficial parotidectomy with preservation of the facial nerve. In our experience the management of patients affected by Warthin's tumors, needs the following steps: CAT scan and NMR examinations to outline multiple and bilateral lesions, fine needle aspiration biopsy, superficial parotidectomy with preservation of the facial nerve, an extended follow-up (10 years after the last surgery).