Influence of risedronate on orthodontic tooth movement in rodents: a systematic review and case report.

INTRODUCTION: Bisphosphonates have an inhibitory impact on osteoclastic activity, reducing bone resorption. However, the influence of risedronate on tooth movement is not well-defined. OBJECTIVE: This systematic review assessed the effect of risedronate intake on orthodontic tooth movement. A case report was also provided. METHODS: Two independent reviewers searched six databases (PubMed, Web of Science, Ovid, Lilacs, Scopus, and Open Grey). The searches were carried out in April/2020, and an update was set in place in June/2023. Therefore, the searches considered a timeline from the databases' inception date until June/2023, with no publication date and/or language restrictions. The clinical question focused on evaluating the orthodontic tooth movement and relapse movement (Outcome) in animals (Population) exposed to risedronate (Exposure), compared to control groups (Comparison). The Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines were applied, and the protocol was registered in PROSPERO (CRD42020168581). The risk of bias was determined using the Systematic Review Centre for Laboratory Animal Experimentation protocol (SYRCLE). RESULTS: Two studies in rats and one in guinea pigs were included in the systematic review. The studies reported a decrease in orthodontic tooth movement, a reduction in the relapse movement, and a reduced number of positive tartrate-resistant acid phosphatase (TRAP) cells, with a significantly reduced number of bone gaps after the administration of risedronate in rats. A case report illustrated the effects of risedronate administration in one patient. CONCLUSION: Based on the systematic review, risedronate seems to impair orthodontic tooth movement and relapse due to a decrease in bone resorption cells.

Orofacial myofunctional therapy associated with the use of the stimulating palatal plate in children with trisomy 21: case studies. / Terapia miofuncional orofacial associada ao uso da placa palatina de memória em crianças com Trissomia do 21: estudo de casos.

Individuals with trisomy 21 may have muscle hypotonia of the speech articulation organs, an enlarged protruding tongue positioned on the floor of the mouth, and a lack of lip closure. The stimulating palatal plate is an intraoral appliance that, associated with myofunctional therapy, aims to improve these children's habitual lip and tongue posture. This study aimed to present the cases of four male children with trisomy 21, with a mean age of 6.7 and a standard deviation of 7.8 months, who used the stimulating palatal plate in association with myofunctional therapy. The children used the plate for 6 months and did exercises based on the orofacial regulation therapy, and their parents received instructions on feeding them and removing deleterious oral habits. In the first session and at the end of the treatment, each child's face was video-recorded for 5 minutes at rest, and two researchers analyzed independently their habitual tongue and lip posture. Participants who began the treatment earlier and had the most severe postural changes had greater tongue and lip posture improvement.

Indivíduos com Trissomia do 21 podem apresentar hipotonia muscular dos órgãos fonoarticulatórios, língua alargada, posicionada no assoalho oral e protrusa e ausência de selamento labial. A placa palatina de memória é um dispositivo intraoral que, associado à terapia miofuncional, visa à melhora da postura habitual dos lábios e da língua dessas crianças. O objetivo deste trabalho foi apresentar os casos de quatro crianças com Trissomia do 21, do sexo masculino, com média de idade de 6,7 e desvio-padrão de 7,8 meses, que fizeram uso da placa palatina de memória de forma associada à terapia miofuncional. As crianças utilizaram a placa por seis meses, realizaram exercícios baseados na terapia de regulação orofacial e receberam orientações quanto à alimentação e retirada de hábitos orais deletérios. Na primeira sessão e ao final do tratamento, foi realizada a gravação de 5 minutos da face de cada criança em repouso e a análise da postura habitual de língua e de lábios foi realizada por dois pesquisadores independentes. Observou-se maior melhora da postura de língua e de lábios dos participantes que iniciaram o tratamento mais precocemente e que apresentavam as alterações posturais mais severas.

Influência da idade e do tempo de uso da Placa Palatina de Memória por crianças com Trissomia do 21 nas mudanças miofuncionais orofaciais percebidas pelos pais, na adaptação e satisfação da família após quatro meses de tratamento / nfluence of age and time of use of the Stimulating Palatal Plate by children with Trisomy 21 on orofacial myofunctional changes perceived by parents, children's adaptation, and family's satisfaction after four months of treatment / Influencia de la edad y el tiempo de uso de la placa de memoria palatina por niños con trisomía 21 sobre los cambios miofuncionales orofaciales percibidos por los padres, adaptación y satisfacción familiar después de cuatro meses de tratamiento

Objetivo: verificar se a idade das crianças com Trissomia do 21 e o tempo de uso por dia da placa palatina de memória influenciam a adaptação da criança à placa, as mudanças miofuncionais orofaciais percebidas pelos pais e a satisfação da família, após quatro meses de tratamento. Métodos: participaram do estudo14 pais ou responsáveis legais de crianças com Trissomia do 21, com idades de 3 a 20 meses. O tratamento com a placa palatina de memória foi realizado durante quatro meses. A adaptação da criança à placa, as mudanças miofuncionais orofaciais percebidas pelos pais e a satisfação das famílias em relação ao tratamento foram investigadas por meio de questionário elaborado pelos autores da pesquisa e respondido pelas mães após quatro meses de tratamento. Resultados: a média de idade das crianças que participaram do estudo foi 10 meses e o desvio-padrão de 4,9 meses. O resultado do questionário indicou associação entre idade e postura de lábios relatada pelos pais com o uso da placa palatina de memória, sendo que todas as crianças menores de 10 meses mantiveram o selamento labial, de acordo com os pais, durante o uso da placa; bem como entre idade e satisfação com o tratamento, sendo que as mães das crianças menores mostraram-se mais satisfeitas. Conclusão: os resultados do estudo indicam que houve associação entre idade e postura de lábios relatada pelos pais com o uso da placa, bem como entre idade e satisfação com o tratamento e sugerem que o tratamento precoce com a placa palatina de memória beneficia as crianças com Trissomia do 21. (AU)

Purpose: to verify if the age of children with Trisomy 21 and the time of use per day of the stimulating palatal plate influence the child's adaptation to the plate, the orofacial myofunctional changes perceived by the parents, and the family's satisfaction, after four months of treatment. Methods: 14 parents or legal guardians of children with Trisomy 21, aged between 3 and 20 months, participated in the study. Treatment with the stimulating palatal plate was carried out for four months. The child's adaptation to the plate, the orofacial myofunctional changes perceived by the parents, and the families' satisfaction with the treatment were investigated through a questionnaire prepared by the research authors and answered by the mothers after four months of treatment. Results: The mean age of the children who participated in the study was 10 months and the standard deviation was 4.9 months. The results of the questionnaire indicated an association between age and lip posture, reported by parents, during the use of the stimulating palatal plate, and all children under 10 months maintained lip closure, according to the parents, during the use of the plate. Age was also associated with satisfaction with the service, as the mothers of younger children were more satisfied. Conclusion: The study results indicate an association between age and lip posture, reported by the parents, during the use of the plate, and between age and satisfaction with the service. Thus, it suggests that early treatment with the stimulating palatal plate benefits children with Trisomy 21. (AU)

Objetivo: verificar si la edad de los niños con Trisomía 21 y el tiempo de uso por día de la placa palatina de memoria influyen en la adaptación del niño a la placa, los cambios miofuncionales orofaciales percibidos por los padres y la satisfacción de la familia, después de cuatro meses de tratamiento. Métodos: Participaron en el estudio 14 padres o tutores legales de niños con trisomía 21, con edades comprendidas entre los 3 y los 20 meses. El tratamiento con la placa de memoria palatina se llevó a cabo durante cuatro meses. La adaptación del niño al plato, los cambios miofuncionales orofaciales percibidos por los padres y la satisfacción de las familias con el tratamiento fueron investigados a través de un cuestionario elaborado por los autores y respondido por las madres, después de cuatro meses de tratamiento. Resultados: La edad media de los niños que participaron en el estudio fue de 10 meses y la desviación estándar fue de 4,9. El resultado del cuestionario indicó una asociación entre la edad y la postura de los labios, reportada por los padres, con el uso de la placa de memoria palatina, y todos los niños menores de 10 meses mantuvieron el sello de los labios, según los padres, durante el uso de la placa de memoria palatina, así como entre la edad y la satisfacción con el servicio. Las madres de niños más pequeños estaban más satisfechas. Conclusión: Los resultados del estudio indican que hubo asociación entre la edad y la postura de los labios, reportada por los padres, con el uso de la placa, así como entre la edad y la satisfacción con el servicio, y sugieren que el tratamiento temprano con la placa de memoria palatina beneficia a los niños con trisomía 21. (AU)

Terapia miofuncional orofacial associada ao uso da placa palatina de memória em crianças com Trissomia do 21: estudo de casos / Orofacial myofunctional therapy associated with the use of the stimulating palatal plate in children with trisomy 21: case studies

RESUMO Indivíduos com Trissomia do 21 podem apresentar hipotonia muscular dos órgãos fonoarticulatórios, língua alargada, posicionada no assoalho oral e protrusa e ausência de selamento labial. A placa palatina de memória é um dispositivo intraoral que, associado à terapia miofuncional, visa à melhora da postura habitual dos lábios e da língua dessas crianças. O objetivo deste trabalho foi apresentar os casos de quatro crianças com Trissomia do 21, do sexo masculino, com média de idade de 6,7 e desvio-padrão de 7,8 meses, que fizeram uso da placa palatina de memória de forma associada à terapia miofuncional. As crianças utilizaram a placa por seis meses, realizaram exercícios baseados na terapia de regulação orofacial e receberam orientações quanto à alimentação e retirada de hábitos orais deletérios. Na primeira sessão e ao final do tratamento, foi realizada a gravação de 5 minutos da face de cada criança em repouso e a análise da postura habitual de língua e de lábios foi realizada por dois pesquisadores independentes. Observou-se maior melhora da postura de língua e de lábios dos participantes que iniciaram o tratamento mais precocemente e que apresentavam as alterações posturais mais severas.

ABSTRACT Individuals with trisomy 21 may have muscle hypotonia of the speech articulation organs, an enlarged protruding tongue positioned on the floor of the mouth, and a lack of lip closure. The stimulating palatal plate is an intraoral appliance that, associated with myofunctional therapy, aims to improve these children's habitual lip and tongue posture. This study aimed to present the cases of four male children with trisomy 21, with a mean age of 6.7 and a standard deviation of 7.8 months, who used the stimulating palatal plate in association with myofunctional therapy. The children used the plate for 6 months and did exercises based on the orofacial regulation therapy, and their parents received instructions on feeding them and removing deleterious oral habits. In the first session and at the end of the treatment, each child's face was video-recorded for 5 minutes at rest, and two researchers analyzed independently their habitual tongue and lip posture. Participants who began the treatment earlier and had the most severe postural changes had greater tongue and lip posture improvement.

Influence of risedronate on orthodontic tooth movement in rodents: a systematic review and case report

ABSTRACT Introduction: Bisphosphonates have an inhibitory impact on osteoclastic activity, reducing bone resorption. However, the influence of risedronate on tooth movement is not well-defined. Objective: This systematic review assessed the effect of risedronate intake on orthodontic tooth movement. A case report was also provided. Methods: Two independent reviewers searched six databases (PubMed, Web of Science, Ovid, Lilacs, Scopus, and Open Grey). The searches were carried out in April/2020, and an update was set in place in June/2023. Therefore, the searches considered a timeline from the databases' inception date until June/2023, with no publication date and/or language restrictions. The clinical question focused on evaluating the orthodontic tooth movement and relapse movement (Outcome) in animals (Population) exposed to risedronate (Exposure), compared to control groups (Comparison). The Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines were applied, and the protocol was registered in PROSPERO (CRD42020168581). The risk of bias was determined using the Systematic Review Centre for Laboratory Animal Experimentation protocol (SYRCLE). Results: Two studies in rats and one in guinea pigs were included in the systematic review. The studies reported a decrease in orthodontic tooth movement, a reduction in the relapse movement, and a reduced number of positive tartrate-resistant acid phosphatase (TRAP) cells, with a significantly reduced number of bone gaps after the administration of risedronate in rats. A case report illustrated the effects of risedronate administration in one patient. Conclusion: Based on the systematic review, risedronate seems to impair orthodontic tooth movement and relapse due to a decrease in bone resorption cells.

RESUMO Introdução: Os bifosfonatos têm um impacto inibitório na atividade osteoclástica, reduzindo a reabsorção óssea. No entanto, a influência do risedronato no movimento dentário não está bem definida. Objetivo: Esta revisão sistemática avaliou o efeito do uso de risedronato no movimento ortodôntico dos dentes. Um relato de caso também é apresentado. Métodos: Dois revisores independentes pesquisaram seis bases de dados (PubMed, Web of Science, Ovid, Lilacs, Scopus e Open Grey), considerando o período de abril de 2020 até junho de 2023, sem restrições de data e/ou idioma de publicação. A questão clínica focou em avaliar o movimento ortodôntico dos dentes e movimento de recidiva (resultado) em animais (população) expostos ao risedronato (exposição) em comparação com grupos de controle (comparação). Foram aplicadas as Diretrizes Preferenciais para Revisão Sistemática e Metanálise (PRISMA) e um protocolo foi registrado no PROSPERO (CRD42020168581). O risco de viés foi determinado utilizando o protocolo do Centro de Revisão Sistemática para Experimentação em Animais de Laboratório (SYRCLE). Resultados: Dois estudos em ratos e um em porquinhos-da-índia foram incluídos na revisão sistemática. Os estudos relataram uma diminuição no movimento ortodôntico dos dentes, uma redução no movimento de recidiva e um número reduzido de células positivas à fosfatase ácida tartarato-resistente (TRAP) com um número significativamente reduzido de falhas ósseas após a administração de risedronato em ratos. Um relato de caso ilustrou os efeitos da administração de risedronato em uma paciente. Conclusão: Com base na revisão sistemática, o risedronato parece interferir no movimento ortodôntico dos dentes e na recidiva devido a uma diminuição nas células de reabsorção óssea.

Effects of using the stimulating palatal plate in combination with orofacial stimulation on the habitual tongue and lip posture in children with trisomy 21: an integrative literature review / Efeitos da placa palatina de memória associada à estimulação orofacial na postura habitual de língua e de lábios de crianças com Trissomia do 21: revisão integrativa da literatura

ABSTRACT Purpose: to verify, in the literature, the effects of using the stimulating palatal plate on lip and tongue posture in children with trisomy 21. Methods: a search was conducted in Medline, LILACS, CINAHL, EMBASE, Scopus, Web of Science, and Cochrane. Original articles designed as clinical trials, longitudinal studies, or case-control studies, approaching stimulating palatal plate in the treatment of children with trisomy 21 and assessing habitual lip and tongue posture as an outcome, were included. Literature Review: a total of 376 studies were found, of which 10 met the selection criteria. They were published between 1996 and 2007 and carried out mostly in Europe, with small samples. The age when they began wearing the plate ranged from 1 month to 5 years, and intervention lasted from 4 to 58 months; in most cases, it was combined with orofacial muscle stimulation. Use frequency ranged from two to four times a day, each period lasting from 30 minutes to 2 hours. The children's tongue and lip posture improved in most pieces of research. Conclusion: studies suggest that using the stimulating palatal plate in combination with orofacial muscle stimulation brings benefits to tongue and lip posture in children presented with trisomy 21.

RESUMO Objetivo: verificar na literatura os efeitos da placa palatina de memória na postura de lábios e língua de crianças com Trissomia do 21. Métodos: foi realizada busca nas bases de dados Medline, Lilacs, CINAHL, Embase, Scopus, Web of Science e Cochrane, com inclusão de artigos originais com delineamentos dos tipos ensaios clínicos, estudos longitudinais ou caso-controle, que abordaram a placa palatina de memória no tratamento de crianças com Trissomia do 21 e avaliaram, como desfechos, a postura habitual de língua e de lábios. Revisão da Literatura: foram encontrados 376 estudos, dos quais dez contemplaram os critérios de seleção. Estes foram publicados entre 1996 e 2007, conduzidos principalmente na Europa, com amostras reduzidas. A idade de instalação da placa variou de um mês a cinco anos e a duração da intervenção de quatro a 58 meses, estando, na maioria, associada à estimulação da musculatura orofacial. A frequência de uso variou de dois a quatro períodos diários de 30 minutos a duas horas. Houve melhora na postura de língua e lábios das crianças na maioria das pesquisas. Conclusão: os estudos sugerem que a placa palatina de memória, associada à estimulação da musculatura orofacial, proporciona benefícios para postura de lábios e língua de crianças com Trissomia do 21.

The First-Year Follow-Up of a Cleft Lip and Palate Patient Treated With Nasoalveolar Molding (NAM).

The objectives of pre-surgical orthopedics are to allow surgical repair with minimal tension of the involved tissues and less restriction to the craniofacial growth. The aim of this study was to evaluate the benefits of nasoalveolar model (NAM) as a pre-operative therapy in a patient with bilateral cleft lip and palate followed by labioplasty and palatoplasty. A 15-day-old patient underwent orthopedic treatment with NAM. After pre-operative treatment, retraction of the pre-maxilla was observed with reduction of the fissure. Due to the successful effects of NAM treatment the patient had a one-step surgery for lip correction. Six months later, due to lip pressure the fissure was further decreased. After six months, the patient underwent palatoplasty. Both surgeries contributed to the remaining closure of the fissure, which were reduced by half compared to the end of pre-operative treatment. The uses of NAM as a pre-operative treatment approached the alveolar segments, centralized the pre-maxilla, decreased the cleft palate resulting in a marked improvement of the arch and provide superior surgical results. In addition, it allows the primary repair of the patient's lip with asymmetric bilateral fissure in only one-step surgery; in consequence, it will reduce treatment morbidity and decrease cost of treatment.

Comparison of the accuracy of virtual and direct bonding of orthodontic accessories.

INTRODUCTION: Conventional direct and indirect bonding techniques fail to obtain the ideal bracket position. OBJECTIVE: To compare the accuracy of virtual and conventional direct bonding of orthodontic accessories. METHODS: A single virtual configuration (dental mannequin with Class I malocclusion) served as basis for generating the reference model (treated virtually) and the intervention models (10 digital models and 10 solid models, obtained by means of prototyping). A total of 560 teeth were then equally distributed between a group of orthodontists (Group I, direct bonding; and Group II, virtual bonding), working in two different time intervals. The individual positions of the accessories were measured after three-dimensional superimposition with customized software. The Student's-t test for paired samples, and Chi-square tests were used for statistical analysis, both at the level of significance of 5%. RESULTS: In comparison of the errors in raw values, there were significant differences only in the vertical (p< 0.001) and horizontal dimensions (p< 0.001). Considering the groups of ranges by clinical limits of the deviations, these differences were significant in the three dimensions, vertical (p< 0.001), horizontal (p= 0.044) and angular (p= 0.044). CONCLUSION: Virtual bonding made it possible to obtain more precise/accurate positioning of the orthodontic accessories. The potential accuracy of this method brings new perspectives to refining the indirect bonding protocols.

Impact of the onset of fixed appliance therapy on adolescents' quality of life using a specific condition questionnaire: A cross-sectional comparison between male and female individuals.

OBJECTIVE: To evaluate the impact of the first six months of orthodontic treatment with fixed appliances on the oral health-related quality of life (OHRQoL) of adolescents, comparing boys and girls, using a specific condition questionnaire. DESIGN: Cross-sectional. SETTING: School of Dentistry of the Federal University of Minas Gerais, Belo Horizonte, Brazil. PARTICIPANTS: Adolescents aged 10-17 years. METHODS: Forty-six adolescents participated in this study. Adolescents' OHRQoL was evaluated using the Brazilian version of the questionnaire Impact of Fixed Appliances Measure. This questionnaire comprises 43 questions distributed across nine domains: aesthetics; functional limitation; dietary impact; oral hygiene impact; maintenance impact; physical impact; social impact; time constraints; and travel/cost/inconvenience implications. The answer options follow the Likert scale, in the range of 1-5. A higher score indicates a more negative impact on the OHRQoL. Adolescents' malocclusion was assessed using the Dental Aesthetic Index. Information on family income, adolescents' age and tooth extraction was also collected. A directed acyclic graph was used to identify potential confounders. Statistical analysis involved the chi-square test, the Student's t test and the analysis of covariance. The minimal clinically important difference was also calculated. RESULTS: Of the 46 participants, 25 were girls and 21 were boys. The female adolescents presented a more negative impact from the orthodontic treatment on the quality of life when compared to the male adolescents (P < 0.001), regardless of the influence of the confounding variables. The most negative repercussions were identified in the domains of oral hygiene (P = 0.002), physical impact (P < 0.001) and social impact (P < 0.001). CONCLUSION: The impact of the first six months of orthodontic treatment on OHRQoL is more negative in female individuals than in male individuals. The results of this study may be useful for the oral healthcare provider during the counselling of adolescents undergoing fixed appliance therapy.

Impact of malocclusion on the quality of life of children aged 8 to 10 years.

OBJECTIVE: The aim of the present cross-sectional study was to assess the impact of malocclusion on the quality of life of children aged 8 to 10 years attending public elementary schools in Belo Horizonte, State of Minas Gerais, Brazil. METHODS: The Brazilian version of the Child Perceptions Questionnaire 8-10 (CPQ8-10) was used to evaluate oral health-related quality of life. The children were examined for the diagnosis of malocclusion using the Dental Aesthetic Index (DAI). The data were analyzed by bivariate and multivariate descriptive statistics using Poisson regression at a 5% significance level. A total of 270 children participated in the study. RESULTS: Children with normal occlusion or mild malocclusion (DAI ≤ 25) were 56% less likely (95%CI: 0.258-0.758; p= 0.003) to have their quality of life affected compared with children diagnosed with extremely severe malocclusion (DAI ≥ 36). Children with a maxillary anterior overjet ≥ 3 mm had higher CPQ8-10 mean scores (19.4; SD = 17.1) than those with an overjet < 3 mm (13.6; SD = 11.7; p= 0.038). CONCLUSIONS: Extremely severe malocclusion and pronounced maxillary anterior overjet were associated with a negative impact on quality of life.

Impact of malocclusion on the quality of life of children aged 8 to 10 years

ABSTRACT Objective: The aim of the present cross-sectional study was to assess the impact of malocclusion on the quality of life of children aged 8 to 10 years attending public elementary schools in Belo Horizonte, State of Minas Gerais, Brazil. Methods: The Brazilian version of the Child Perceptions Questionnaire 8-10 (CPQ8-10) was used to evaluate oral health-related quality of life. The children were examined for the diagnosis of malocclusion using the Dental Aesthetic Index (DAI). The data were analyzed by bivariate and multivariate descriptive statistics using Poisson regression at a 5% significance level. A total of 270 children participated in the study. Results: Children with normal occlusion or mild malocclusion (DAI ≤ 25) were 56% less likely (95%CI: 0.258-0.758; p= 0.003) to have their quality of life affected compared with children diagnosed with extremely severe malocclusion (DAI ≥ 36). Children with a maxillary anterior overjet ≥ 3 mm had higher CPQ8-10 mean scores (19.4; SD = 17.1) than those with an overjet < 3 mm (13.6; SD = 11.7; p= 0.038). Conclusions: Extremely severe malocclusion and pronounced maxillary anterior overjet were associated with a negative impact on quality of life.

RESUMO Objetivo: o objetivo do presente estudo transversal foi avaliar o impacto da má oclusão na qualidade de vida de crianças na faixa etária de 8 a 10 anos de idade, estudantes de escolas da rede pública da cidade de Belo Horizonte, estado de Minas Gerais, Brasil. Métodos: o instrumento utilizado para medir a qualidade de vida relacionada à saúde bucal foi a versão brasileira do Child Perceptions Questionnaire 8-10 (CPQ8-10). As crianças foram examinadas para diagnóstico de má oclusão utilizando-se o Dental Aesthetic Index (DAI). A análise dos dados foi realizada por meio de estatística descritiva, bivariada e multivariada por meio da regressão de Poisson, com nível de significância de 5%. Participaram do estudo 270 crianças. Resultados: crianças com oclusão normal ou má oclusão leve (DAI ≤25) apresentaram 56% menos probabilidade (IC 95%: 0,258-0,758; p= 0,003) de impacto na qualidade de vida, comparadas com crianças diagnosticadas com má oclusão muito grave (DAI ≥ 36). Crianças com sobressaliência superior anterior ≥ 3 mm apresentaram maiores escores médios de CPQ8-10 (19,4; DP = 17,1) do que aqueles com sobressaliência < 3 mm (13,6; DP=11,7; p= 0,038). Conclusões: a má oclusão muito grave e a sobressaliência superior anterior aumentada se associaram ao impacto negativo na qualidade de vida.

Multidisciplinary oral rehabilitation in partially edentulous adult patients with malocclusion: A cross-sectional survey study.

BACKGROUND: A cross-sectional survey was conducted to gather information regarding the opinion of Brazilian specialists in both orthodontics and implantology on multidisciplinary oral rehabilitation in partially edentulous patients with malocclusion. MATERIAL AND METHODS: A total of 305 specialists participated in a telephone survey and answered an ad hoc 10-item questionnaire, including the request of total skull cone-beam tomographies (CBCT) and the use of 3D digital planning software, the best moment of treatment to place dental implants, and the integration of orthodontics in implantology. RESULTS: Most participants did not request CBCT (90.8%) or 3D digital planning software images (92.3%) to diagnose and plan multidisciplinary oral rehabilitation. By contrast, 91.1% of participants would use an already dental implant as anchorage for orthodontics, 73.8% had already used implants for this purpose, 47.9% selected 4 months as the waiting time between implant placement and its use as anchorage, and 58.4% had already placed dental implants having in mind using them as anchorage for orthodontics and anticipating the oral rehabilitation process. Moreover, 93.4% of participants stated to avoid applying orthodontic forces in implants with unfavourable prognosis. A total of 67.9% of participants got the degree of specialist in Orthodontics before that of specialist in Implantology. The main reason for obtaining the other specialty degree was to be able to thoroughly exercise the two specialties. CONCLUSIONS: The use of technological advances, such as CBCT and 3D digital planning software was limited. Most dental specialists would wait the osseointegration recommended time before applying orthodontic forces and thus using them as anchorage for orthodontics. The majority of interviewed dentists sought the other specialty to acquire multidisciplinary knowledge. Key words:Cross-sectional study, orthodontics, implantology, partially edentulous, malocclusion, oral rehabilitation.

A reabilitação oral multidisciplinar para pacientes adultos edêntulos parciais portadores de má oclusão Trilogia parte 1: a solicitação de tomografias de feixe cônico total do crânio e o uso de softwares tridimensionais de planejamento digital / Multidisciplinary oral rehabilitation for adult partial edentulous patients with malocclusion Trilogy part 1: the request of total skull cone beam tomographies and the use of three-dimensional digital planning software

Uma tomografia de feixe cônico total do crânio associada a um software tridimensional de planejamento digital permite um diagnóstico mais completo e a simulação de diferentes planos de tratamento para a reabilitação oral multidisciplinar de pacientes adultos edêntulos parciais portadores de má oclusão. Um total de 305 cirurgiões-dentistas especialistas, simultaneamente em Ortodontia e em Implantodontia, foram entrevistados e responderam a um questionário com o objetivo de coletar informações importantes sobre a integração da Ortodontia com a Implantodontia para a instalação de implantes dentários em pacientes adultos edêntulos parciais que também necessitam de tratamento ortodôntico. Este estudo foi dividido em uma trilogia de artigos científicos. Esta, a Parte 1, refere-se a perguntas sobre a solicitação de uma tomografia de feixe cônico total do crânio e o uso de softwares tridimensionais de planejamento digital para diagnosticar e planejar reabilitações orais multidisciplinares em pacientes adultos edêntulos parciais portadores de má oclusão. Como a tecnologia já está disponível, era de se esperar uma maior solicitação de tomografias de feixe cônico total do crânio e um maior uso de softwares tridimensionais de planejamento digital por cirurgiões-dentistas, especialistas simultaneamente em Ortodontia e em Implantodontia, mas os resultados mostram o contrário.(AU)

A total skull cone beam tomography associated to a three-dimensional digital planning software permits a more complete diagnostic and the simulation of different treatment plans for the multidisciplinary oral rehabilitation of partially edentulous adult patients with malocclusion. A total of 305 dental specialists in both orthodontics and implantology were interviewed and answered a questionnaire in order to collect relevant information about the integration of orthodontics to implantology for the placement of dental implants on partially edentulous adult patients that also need orthodontic treatment. This study was divided in a trilogy of scientific articles. This, the Part 1, refers to questions about the request of a total skull cone beam tomography and the use of three-dimensional planning softwares to diagnose and plan a multidisciplinary oral rehabilitation for partially edentulous adult patients with malocclusion. As technology is already available, it was expected a higher number of dental specialists in both orthodontics and implantology requesting a total skull cone beam tomography and a greater use of three-dimensional digital planning softwares. But results show the opposite. (AU)

A reabilitação oral multidisciplinar para pacientes adultos edêntulos parciais portadores de má oclusão Trilogia parte 3: a integração da Ortodontia com a Implantodontia / Multidisciplinary oral rehabilitation for partial edentulous adult patients with malocclusion Trilogy part 3: the integration of Orthodontics with Implantology

Para se conduzir uma reabilitação oral multidisciplinar em um paciente adulto edêntulo parcial portador de má oclusão deve haver uma equipe de cirurgiões-dentistas especialistas trabalhando sincronizadamente. Juntos, devem definir qual é o melhor plano de tratamento que integre a Ortodontia com a Implantodontia para a obtenção de uma oclusão estável e harmonização facial. No entanto, se um único cirurgião-dentista pretende conduzir uma reabilitação oral multidisciplinar em um paciente adulto edêntulo parcial portador de má oclusão, ele deve reunir habilidades multidisciplinares para competentemente diagnosticar, planejar e conduzir o caso. Um total de 305 cirurgiões-dentistas especialistas simultaneamente em Ortodontia e em Implantodontia foram entrevistados e responderam a um questionário para coletar importantes informações sobre a integração da Ortodontia com a Implantodontia para a instalação de implantes dentários em pacientes adultos edêntulos parciais, que também necessitam de tratamento ortodôntico. Este estudo foi dividido em uma trilogia de artigos científicos. Esta, a Parte 3, refere-se às perguntas sobre a primeira formação especializada desses cirurgiões-dentistas e os motivos que os levaram a cursar outra especialidade para integrar a Ortodontia com a Implantodontia. Os resultados demonstraram que a maioria dos cirurgiões-dentistas entrevistados buscou adquirir conhecimentos multidisciplinares, mas que a busca por maiores ganhos financeiros também foi um dos principais motivos para a obtenção de outro título de especialista.(AU)

In pursuance of conducting a multidisciplinary oral rehabilitation for a partially edentulous adult patient with malocclusion, there must be a dental specialist team working synchronically. Together they must define the most suitable treatment plan to accomplish stable occlusion and facial harmonization. However, if one single dentist intends to conduct a multidisciplinary oral rehabilitation for a partially edentulous adult patient with malocclusion, he should have the expertise in multiple specialties to competently diagnose, plan and conduct the case. A total of 305 dental specialists in both orthodontics and implantology were interviewed and answered a questionnaire in order to collect relevant information about the integration of orthodontics to implantology to place dental implants on partially edentulous adult patients that also need orthodontic treatment. This study was divided in a trilogy of scientific articles. This, the Part 3, refers to questions about their first post graduate training and the reasons that led them to get another specialist title to integrate orthodontics to implantology. The results showed that the majority of interviewed dentists sought to acquire multidisciplinary knowledge. But the surch for greater financial gains was also one of the main reasons for obtaining another specialist title.(AU)

Mini-implante como estratégia de tratamento para reabilitação protética temporária ­ relato de caso / Mini-implant as treatment strategy for temporary prosthetic rehabilitation ­ case report

A avulsão de incisivos permanentes gera um problema estético e funcional para o paciente e seu manejo clínico representa um desafio na odontologia. O sucesso do tratamento depende de vários fatores como a idade do paciente, a quantidade e qualidade óssea da região edêntula, a discrepância óssea e o tipo de maloclusão encontrada. Ressalta-se a importância de minimizar efeitos colaterais nas unidades de ancoragem, garantindo ao mesmo tempo função e estética ao longo dos tratamentos ortodôntico e protético, requeridos na maioria dos casos. O objetivo desse artigo é apresentar através de um relato de caso a versatilidade dos mini-implantes na reabilitação temporária de incisivos permanentes em indivíduos em fase de crescimento e desenvolvimento facial. Um menino de 9 anos que apresentava relação de molar em Classe I e mesialização dos incisivos laterais, caninos e pré-molares superiores devido à ausência dos incisivos centrais superiores, que foram avulsionados, foi tratado. Ao final de 1 ano e 8 meses de tratamento, pôde-se estabelecer uma intercuspidação dentária aceitável e espaço adequado para confecção das coroas provisórias sobre os parafusos. O acompanhamento radiográfico foi realizado através de radiografias periapicais e panorâmicas. Na literatura,estudos mostram que os mini-implantes contribuem para a manutenção da quantidade e qualidade óssea do processo alveolar, reduzindo a necessidade de futuras cirurgias de enxerto antes da fixação dos implantes osseointegrados. Dessa forma, esse caso mostrou que a ancoragem esquelética com mini-implantes ortodônticos autoperfurantes auxilia na reabilitação de pacientes que ainda não possuem uma idade óssea suficiente para receberem implantes dentários osseointegrados.(AU)

The avulsion of permanent incisors creates an esthetic and functional problem for the patient and its clinical management is a challenge in dentistry. Treatment success depends on several factors such as patient age, the quantity and quality of edentulous bone area, bone discrepancy and the type of malocclusion found. The importance of minimizing side effects in the anchoring units should be emphasized, while ensuring function and esthetics during the orthodontic and prosthetic treatment required in most cases. The aim of this paper is to present through a case report the versatility of mini-implants in the temporary rehabilitation of permanent incisors in individuals in the growth and facial development phase. A 9-yearold boy who had molar relationship in Class I and mesial movement of the lateral incisors, canines and premolars due to the absence of the elements 11 and 21, which were avulsed, was treated. After 1 year and 8 months of treatment, it was possible to establish an acceptable dental intercuspidation and enough space for the manufacturing of pontics on the screws. The radiographic monitoring was performed by periapical and panoramic radiographies. In literature studies show that the mini-implants contribute to the maintenance of bone quantity and quality of the alveolar process, reducing the need for future bone grafting surgeries before fixation of dental implants. So this case showed that the skeletal anchorage with selfdrilling orthodontic mini-implants helps in the rehabilitation of patients who lack sufficient bone age to receive osseointegrated dental implants.(AU)

Prosthetic Rehabilitation of Child Victim of Avulsion of Anterior Teeth with Orthodontic Mini-Implant.

The treatment of choice in cases of avulsed permanent teeth is the immediate reimplantation. However, this conduct does not always work favorably, either by failures in the initial approach or by inappropriate interventions. In this sense, the aim of this study is to present an alternative prosthetic rehabilitation with the use of orthodontic mini-implants in the anterior region. This case reports a ten-year-old child with history of avulsion of superior central incisors. The therapeutic approach was planned to promote physiological teeth contacts and acceptable esthetics and phonetics. First, the occlusal-gingival insertion of two orthodontic mini-implants was performed in the alveolar ridge, and, immediately after that, two provisional crowns were attached to the implants. The interventions achieved satisfactory cosmetic and functional results. After one-year follow-up, the adjacent periodontal tissues remained without signs and/or symptoms of inflammation. The provisional crowns presented no mobility and fractures. During radiographic examination, a healthy bone tissue appearance was observed. The simplicity of mini-implant installation makes them a promising alternative for temporary prosthetic rehabilitation of patients undergoing growth and development. The technique provides positive aesthetic and functional results that may reflect on self-esteem and social inclusion of children and adolescents.

Effect of chlorhexidine varnish on gingival growth in orthodontic patients: a randomized prospective split-mouth study.

INTRODUCTION: Fixed orthodontic appliances patients suffer limitations on the effective control of biofilm by mechanical methods, bringing the need of a coadjutant in the control of inflammation and oral health improvement. OBJECTIVE: The aim of this prospective split-mouth blind study was to analyze the effect of a 40% chlorhexidine (CHX) varnish on gingival growth of patients with orthodontic fixed appliances. METHODS: Healthy teenage patients with fixed orthodontic appliances and increased gingival volume were recruited (n = 30). Each individual was his own control, having in the maxilla one control side and one treatment side. An application of varnishes occurred on the vestibular area of the upper premolars and first molar crowns, on the control side (placebo varnish) and on the experimental side (EC40(r) Biodentic CHX varnish). The varnishes and sides were randomly chosen and its identification and group was kept by a third party observer and it was not revealed to the researchers and participants until the end of study. In order to establish a baseline registration, digital photographs were taken by a trained photographer before varnish application at baseline (T0), as well as 14 days (T14) and 56 days (T56) after the application. The gingival volume was calculated indirectly using the vestibular areas (mm2) of the upper second premolars' clinical crowns by RapidSketch(r) software, at all study times. The data were analyzed using ANOVA and the Turkey-Krammer test. RESULTS: It was observed, in the final sample of 30 individuals, that at T0, the control and treatment groups were similar. At T14 and T56, a progressive reduction of the clinical crown area was seen in the control group, and an increase in the average area was detected in the experimental group (p < 0,05). CONCLUSIONS: The use of 40% CHX varnish decreases the gingival overgrowth in patients undergoing orthodontic treatment. Further studies are necessary to set the action time and frequency of application.

Comparative Study of the Effect of Acid Etching on Enamel Surface Roughness between Pumiced and Non-pumiced Teeth.

BACKGROUND: The objective was to perform a comparative analysis of the effect of acid etching on enamel roughness between pumiced and non-pumiced teeth. MATERIALS AND METHODS: The sample was composed of 32 dental surfaces divided into two groups: Group 1-16 surfaces having received pumice prophylaxis; and Group 2-16 surfaces not having received pumice prophylaxis. The teeth were kept in saline until the first record of surface roughness prior to etching. For each surface, a roughness graph was obtained through trials using a surface roughness tester. This procedure was repeated two more times at different locations for a total of three readings which, later, were converted in a mean value. The teeth were then acid etched with a 37% phosphoric acid for 60 s, rinsed with water, air dried, and tested with the roughness tester again using the same protocol described for baseline. The Quantikov image analysis program was used to measure the length of the graphs. The average value of the lengths was recorded for each surface before and after etching. The increase in roughness caused by acid etching was calculated and compared between groups. RESULTS: The mean increase in roughness caused by the etching was 301 µm (11.37%) in Group 1 and 214 µm (8.33%) in Group 2. No statistically significant difference was found between samples with and without pumice prophylaxis (P = 0.283). CONCLUSION: The present study showed that the effect of acid etching on enamel roughness was not significantly affected by prior pumice prophylaxis.

Effect of chlorhexidine varnish on gingival growth in orthodontic patients: a randomized prospective split-mouth study

Introduction: Fixed orthodontic appliances patients suffer limitations on the effective control of biofilm by mechanical methods, bringing the need of a coadjutant in the control of inflammation and oral health improvement.Objective: The aim of this prospective split-mouth blind study was to analyze the effect of a 40% chlorhexidine (CHX) varnish on gingival growth of patients with orthodontic fixed appliances. Methods: Healthy teenage patients with fixed orthodontic appliances and increased gingival volume were recruited (n = 30). Each individual was his own control, having in the maxilla one control side and one treatment side. An application of varnishes occurred on the vestibular area of the upper premolars and first molar crowns, on the control side (placebo varnish) and on the experimental side (EC40(r) Biodentic CHX varnish). The varnishes and sides were randomly chosen and its identification and group was kept by a third party observer and it was not revealed to the researchers and participants until the end of study. In order to establish a baseline registration, digital photographs were taken by a trained photographer before varnish application at baseline (T0), as well as 14 days (T14) and 56 days (T56) after the application. The gingival volume was calculated indirectly using the vestibular areas (mm2) of the upper second premolars' clinical crowns by RapidSketch(r) software, at all study times. The data were analyzed using ANOVA and the Turkey-Krammer test.Results:It was observed, in the final sample of 30 individuals, that at T0, the control and treatment groups were similar. At T14 and T56, a progressive reduction of the clinical crown area was seen in the control group, and an increase in the average area was detected in the experimental group (p < 0,05).Conclusions: The use of 40% CHX varnish decreases the gingival overgrowth in patients undergoing orthodontic treatment. Further studies are necessary to set the action time and frequency of application.

Introdução: pacientes com aparelhos ortodônticos fixos sofrem limitações no controle efetivo de biofilme por métodos mecânicos, trazendo a necessidade de um coadjuvante no controle na inflamação e melhora na saúde bucal.Objetivo:esse estudo cruzado prospectivo randomizado teve como objetivo analisar o efeito do verniz de clorexidina (CHX) a 40% no crescimento gengival de pacientes com aparelhos ortodônticos fixos.Métodos:indivíduos adolescentes com aparelhos ortodônticos fixos e aumento de volume gengival foram recrutados para a pesquisa (n = 30). Cada participante atuou como seu próprio controle, tendo, na maxila, um lado controle e um tratamento. No lado controle, aplicou-se verniz placebo e no lado experimental, o verniz EC40(r) Biodentic CHX, ambos na face vestibular das coroas dos pré-molares e primeiro molar superiores. Os vernizes e lados foram escolhidos de forma aleatória e a identificação deles e a que grupo pertenciam foi mantida por um terceiro observador, não sendo revelada aos pesquisadores nem aos participantes até o final do estudo. Fotografias digitais foram tiradas por um fotógrafo treinado, antes da aplicação do verniz no tempo inicial (T0), bem como 14 dias (T14) e 56 dias (T56) após a aplicação. O volume gengival foi calculado indiretamente, por meio das áreas vestibulares (mm2) das coroas dos segundos pré-molares superiores, com o softwareRapidSketch(r), em todos os tempos de estudo. Os dados foram analisados usando ANOVA e teste de Turkey-Krammer.Resultados:na amostra final de 30 indivíduos, observou-se que, em T0, os grupos controle e tratamento foram semelhantes. Já em T14 e T56, foi observada uma progressiva redução na área da coroa clínica no grupo controle, e um aumento na área média do grupo experimental (p< 0,05).Conclusão:o uso do verniz de CHX a 40% diminui o excessivo crescimento gengival em pacientes sob tratamento ortodôntico. Estudos futuros são necessários para se determinar o tempo de ação e a frequência de aplicação.