Parafunctions, Signs and Symptoms of Temporomandibular Disorders (TMD), in Children with Attention-Deficit Hyperactivity Disorder (ADHD): the results of the SOPKARD-Junior study / Parafunkcje, oznaki i objawy zaburzen czynnosciowych narzadu zucia (TMD) u dzieci z zespolem nadpobudliwosci psychoruchowej z deficytem uwagi (ADHD): wyniki badania SOPKARD-Junior

OBJECTIVES: The aim of the study was to compare the prevalence of parafunctions and signs and symptoms of TMD in a population group of children with and without ADHD. METHODS: The study included all 5th grade children of all public primary schools in Sopot (untreated, unguided children). The reporting rate was 91%. At the first stage of the psychological-psychiatric study both parents and children filled in the CBCLand YSR questionnaires. At the next stage, in the group of children selected during the screening, aqualified child psychiatrist conducted asemi-structured diagnostic interview K-SADS-PLand diagnosed ADHD. Parafunctions, signs and symptoms of TMD were assessed by conducting a direct interview with a child and a clinical examination by a dentist. RESULTS: There were significant differences (p < 0.05) between children with ADHD and without ADHD associated with parafunctions such as chewing gum (76.47% vs. 46.07%), nail biting (70.59% vs. 40.45%) and bruxism (52.54% vs. 26.22%), the number of signs and symptoms of TMD (1 sign or symptom 0.0% vs. 32.21%; 4-7 signs or symptoms 17.65% vs. 3.75%). CONCLUSIONS: In children with ADHD, symptoms of temporomandibular joint disorders and parafunctions were significantly more frequent. These studies suggest that children with ADHD constitute agroup of increased risk for TMD in the future. Interdisciplinary treatment of an ADHD patient by a psychiatrist and a dentist is necessary.

IL-1ß, TNF-α, and IL-6 levels in gingival fluid and serum of patients with ischemic stroke.

It has been documented that an increase of immune cells in periodontitis may stimulate the process of atherosclerosis and lead to ischemic stroke. The aim of this study was to investigate whether there is any significant difference in serum and gingival crevicular fluid (GCF) cytokine concentrations between patients with early ischemic stroke (IS) and a control group. Eighty-six patients were consecutively enrolled for this study, 50 with ischemic stroke and 36 as a control group with no previous stroke. Only dentulous patients were included. In each patient, GCF was collected from the deepest periodontal pocket. Blood serum samples were also taken from all subjects. The collected material was analyzed for cytokine concentrations using the cytometric bead array technique. Cerebral ischemia was found to be correlated with higher serum levels of IL-1ß (13.01 ± 13.87 vs. 7.83 ± 2.11) and IL-6 (15.82 ± 16.64 vs. 6.64 ± 2.5) compared to the control group. The levels of IL-1, IL-6 and TNF-α in GCF were higher in patients with ischemic stroke but the difference was not significant. In conclusion, ischemic stroke was found to be associated with higher levels of IL-1ß and IL-6 in serum. The cytokine concentrations in GCF did not appear to be directly correlated with those in serum in patients with ischemic stroke.(J Oral Sci 58, 509-513, 2016).