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1.
Phys Med Biol ; 57(9): 2555-73, 2012 May 07.
Artículo en Inglés | MEDLINE | ID: mdl-22491034

RESUMEN

Vessel diseases are a very common reason for permanent organ damage, disability and death. This fact necessitates further research for extracting meaningful and reliable medical information from the 3D DSA volumes. Murray's law states that at each branch point of a lumen-based system, the sum of the minor branch diameters each raised to the power x, is equal to the main branch diameter raised to the power x. The principle of minimum work and other factors like the vessel type, impose typical values for the junction exponent x. Therefore, deviations from these typical values may signal pathological cases. In this paper, we state the necessary and the sufficient conditions for the existence and the uniqueness of the solution for x. The second contribution is a scale- and orientation- independent set of features for stenosis classification. A support vector machine classifier was trained in the space of these features. Only one branch was misclassified in a cross validation on 23 branches. The two contributions fit into a pipeline for the automatic detection of the cerebral vessel stenoses.


Asunto(s)
Angiografía de Substracción Digital/métodos , Encéfalo/irrigación sanguínea , Trastornos Cerebrovasculares/diagnóstico por imagen , Imagenología Tridimensional/métodos , Automatización , Trastornos Cerebrovasculares/patología , Constricción Patológica/diagnóstico por imagen , Constricción Patológica/patología , Humanos , Modelos Anatómicos
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