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1.
Br J Dermatol ; 176(4): 1064-1067, 2017 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-27479792

RESUMEN

A small subset of patients with infantile haemangiomas (IHs) can present with serious complications, the most common of which is ulceration. Ulcerated IHs can be extremely painful and always result in scarring. Numerous studies support the efficacy and reduced side-effects of propranolol relative to systemic corticosteroids, which led to the adoption of propranolol as the mainstay of IH treatment. However, in certain cases of IH with complex ulceration, propranolol monotherapy may not be sufficient. In this case report, we present two cases that illustrate the effectiveness of the adjunctive use of oral corticosteroids for the treatment of select IHs with recalcitrant painful ulceration, which were refractory to conservative wound care, laser therapy and oral propranolol. We suggest a continuing niche role for the brief use of corticosteroids as an effective adjunct to oral propranolol in managing a subset of complex IHs complicated by intractable ulceration.


Asunto(s)
Glucocorticoides/administración & dosificación , Hemangioma/tratamiento farmacológico , Propranolol/administración & dosificación , Neoplasias Cutáneas/tratamiento farmacológico , Úlcera Cutánea/etiología , Vasodilatadores/administración & dosificación , Administración Oral , Enfermedad Crónica , Quimioterapia Combinada , Hemangioma/complicaciones , Humanos , Lactante , Masculino , Prednisolona/administración & dosificación , Neoplasias Cutáneas/complicaciones , Úlcera Cutánea/tratamiento farmacológico , Resultado del Tratamiento
3.
Clin Radiol ; 69(5): 443-57, 2014 May.
Artículo en Inglés | MEDLINE | ID: mdl-24529409

RESUMEN

Classification of vascular anomalies (VAs) is challenging due to overlapping clinical symptoms, confusing terminology in the literature and unfamiliarity with this complex entity. It is important to recognize that VAs include two distinct entities, vascular tumours (VTs) and vascular malformations (VaMs). In this article, we describe SE Mitchell Vascular Anomalies Flow Chart (SEMVAFC), which arises from a multidisciplinary approach that incorporates clinical symptoms, physical examination and magnetic resonance imaging (MRI) findings to establish International Society for the Study of Vascular Anomalies (ISSVA)-based classification of the VAs. SEMVAFC provides a clear visual pathway for physicians to accurately diagnose Vas, which is important as treatment, management, and prognosis differ between VTs and VaMs.


Asunto(s)
Sistemas de Apoyo a Decisiones Clínicas , Imagen por Resonancia Magnética , Examen Físico , Malformaciones Vasculares/diagnóstico , Neoplasias Vasculares/diagnóstico , Femenino , Humanos , Masculino , Terminología como Asunto , Malformaciones Vasculares/clasificación , Neoplasias Vasculares/clasificación
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