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1.
PLoS One ; 7(11): e50234, 2012.
Artículo en Inglés | MEDLINE | ID: mdl-23226250

RESUMEN

Lipomas are common benign tumours of fat cells. In most cases, surgical excision is curative and simple to perform; however, such a procedure requires general anaesthesia and may be associated with delayed wound healing, seroma formation and nerve injury in deep and intramuscular tumours. The objective of this study was to evaluate treatment of subcutaneous, subfascial or intermuscular lipomas using intralesional steroid injections in dogs. Fifteen dogs presenting with lipomas were selected for treatment with ultrasound-guided intralesional injection of triamcinolone acetonide at a dose of 40 mg/mL. Nine subcutaneous and subfascial tumours showed a complete regression. The other lipomas decreased in diameter, achieving, in some cases, remission of discomfort and regression of lameness. Steroid injection was a relatively safe and effective treatment for lipomas in dogs; only six dogs experienced polyuria/polydipsia for about 2 weeks post-treatment.


Asunto(s)
Glucocorticoides/administración & dosificación , Cojera Animal/tratamiento farmacológico , Lipoma/tratamiento farmacológico , Triamcinolona Acetonida/administración & dosificación , Animales , Perros , Femenino , Glucocorticoides/efectos adversos , Inyecciones Intralesiones , Cojera Animal/patología , Lipoma/patología , Masculino , Polidipsia/fisiopatología , Triamcinolona Acetonida/efectos adversos
2.
Vet Ophthalmol ; 12(2): 97-101, 2009.
Artículo en Inglés | MEDLINE | ID: mdl-19261164

RESUMEN

OBJECTIVE: To describe a case of a conjunctivo-corneal mass in a cat associated with acid-fast bacilli. METHODS: A 2-year-old female black European Short-Hair cat, living outdoors in a suburban environment in Italy, was referred for evaluation of a nodular, vascularized mass of 2 weeks duration. The mass involved the dorsal bulbar conjunctiva at the temporal canthus of OS and invaded the sclera and cornea. Routine ophthalmic and systemic examination, serologic testing, cytology and histology of the mass were performed. Mycobacterium specific polymerase chain reaction (PCR) of variable regions 1, 2 and 3 of the 16S ribosomal RNA (rRNA) gene was also performed. RESULTS: Neutrophils, lymphocytes, macrophages and giant cells with intracytoplasmic acid-fast bacilli were seen on cytological examination. The histological examination confirmed the presence of a granulomatous lesion with acid-fast bacilli within macrophages. Bacteriological culture of the material from the lesion was negative for Mycobacterium spp. Mycobacterium 16S rRNA gene specific PCR was positive. A diagnosis of feline leprosy was made. The owners refused any treatment, and 1 year later the lesion was still present. CONCLUSIONS: Veterinary ophthalmologists should be aware of conjunctivo-corneal leproma as an unusual symptom of leprosy.


Asunto(s)
Enfermedades de los Gatos/microbiología , Enfermedades de la Conjuntiva/microbiología , Enfermedades de la Conjuntiva/veterinaria , Enfermedades de la Córnea/veterinaria , Granuloma/veterinaria , Lepra Lepromatosa/veterinaria , Animales , Enfermedades de los Gatos/patología , Gatos , Enfermedades de la Conjuntiva/patología , Enfermedades de la Córnea/microbiología , Enfermedades de la Córnea/patología , Femenino , Granuloma/microbiología , Granuloma/patología , Italia/epidemiología , Lepra Lepromatosa/patología
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