RESUMEN
UNLABELLED: The study was performed on 313 patients hospitalized in an acute geriatric unit during a six-month period and aimed at determine the prevalence of adverse drug events (ADE) and the preventability of them. METHODS: ADE were determined by the medical information unit. Preventability was determined by inadequacy with standards of care, medication-related factors (non respect of contra-indication) and explicit lists of harmful medication in the elderly. RESULTS: prevalence of ADE was 12.7%. The mean age of patients was 84.8 years old. The number of comorbidities per patient was 3 and medications consumed were 7.7±3.1. 70% of them were ambulatory patient with an activity of daily living of 3.8±1.76. Cardiovascular (39%), psychotropic (36.6%) and morphinic (7.3%) medicines were the most frequently involved. The symptoms that occurred most frequently were haemorragia (28.6%), falls (14.3%), and sleepiness (9.5%) and were preventable in 31% of cases. CONCLUSION: elderly patients with multiple pathologies are at high risk for ADE. These ADE are preventable by using scores, following standards of care, respecting contra-indications of medications.
Asunto(s)
Efectos Colaterales y Reacciones Adversas Relacionados con Medicamentos , Psicotrópicos , Humanos , PrevalenciaRESUMEN
An 87-year-old patient was found to have an unusually protrusive hyperostosis frontalis interna, discovered on MRI examination during an assessment of cognitive decline. Neuropsychological evaluation suggested direct repercussions of the frontal lobe compression on executive functions, as well as psychiatric disorders and possibly memory loss.