[Data for substantiation of MPEL of 1,2,4-triazole in the workplace air]. / Materialy k obosnovaniiu PDK 1,2,4-triazola v vozdukhe rabochei zony.

1,2,4-Triazole belongs to the 3-d degree moderately dangerous compounds, according to the parameters of acute intragastric toxicity (LD50). Single and repeated applications of the substance on the skin of rats does not lead to local irritating or skin-resorptive effects. In the native state the substance produces moderate irritating effects on the eye mucosa of rabbits. It produces a moderately manifest cumulative effect of the functional character (Kcum greater than 5). 1,2,4-Triazole belongs to the 2-nd degree of danger according to LC50. The threshold of acute inhalational exposure (Li(mac)) 226.6 mg/m3, the threshold of chronic inhalational exposure (Lim(ch)), 19.8 mg/m3. The substance does not have mutagenic and embryotropic properties. 5 mg/m3 is recommended as the maximum allowable concentration for 1,2,4-triazole in the air of the working area.

[Data for the establishment of maximum allowable concentration of chlorophenoxypinacoline in the working zone air]. / Materialy k obosnovaniiu predel'no dopustimoi kontsentratsii khlorfenoksipinakolina v vozdukhe rabochei zony.

Chlorophenoxypinacoline with its acute intragastric toxicity LD50 can be attributed to the 3rd class compounds of hazardousness (moderate hazardous substances). Local irritation and skin resorption effects were not revealed. Irritation of the mucous in the eyes in rabbits was moderate and functional cumulation was insignificant. Average lethal concentration (LC50) was not attained. The threshold of acute inhalation and irritation action (Limac, Limir) was at 1093 mg/m3, the threshold of chronic inhalation action (Limch) was at 165.2 mg/m3. No signs of specific mutagenic and embryotropic action were found. The accepted MAC for chlorophenoxypinacoline in the working zone air is 10 mg/m3. The aggregate condition aerosol, 3rd degree of hazardousness.