Shell-bearing Bivalvia and Gastropoda from a rocky shore in the Central Caribbean of Colombia.

This study documents the natural accumulation of mollusk shells on an elevated rocky shore carved into the calcareous rocks of the La Popa formation at Punta Roca (Atlántico), covering an estimated area of 0.35 km2. Hydrodynamic transport and differential exposure to environmental conditions are the primary factors contributing to shell deposition. A total of 58 mollusk species were identified, including 30 bivalves and 28 gastropods. The Veneridae was the most prominent, with the highest number of species (7) and shells comprising 64.22 % of the total. Key species contributing to the accumulation include the bivalves Anomalocardia cf. flexuosa, Polymesoda cf. arctata, Leukoma pectorina, Tivela mactroides, Crassostrea rhizophorae, and the gastropod Vitta virginea. These species are primarily characteristic of estuarine environments, with the exception of T. mactroides. Notably, the first recorded occurrence of the non-native gastropod Naria turdus (Cypraeidae) on the Colombian Caribbean coast was documented. The accumulations exhibit varying degrees of abrasion, fragmentation, encrustation, and bioerosion, with some shells appearing almost intact, indicating differences in origin and transport mechanisms. The extraction of shells for ornamental purposes poses a significant challenge to this natural accumulation.

Enhancing Key Management in LoRaWAN with Permissioned Blockchain.

Low-Power Wide-Area Network (LPWAN) is one of the enabling technologies of the Internet of Things (IoT), and focuses on providing long distance connectivity for a vast amount of smart devices. Currently, LoRa is one of the leading LPWAN solutions available for public use. In LPWANs, especially in LoRa, security is a major concern due to the resource constraints of the devices, the sensitivity level of the transmitted data, the large amount of connected devices, among other reasons. This paper studies the key management mechanism of LoRaWAN environments. A secure architecture for key management based on smart contracts and permissioned blockchain to enhance security and availability in LoRaWAN networks is proposed. To demonstrate the feasibility of the proposed blockchain-based LoRaWAN architecture, a working prototype has been created using open-source tools and commodity hardware. Performance analysis shows that the prototype presents similar execution time and latency values, when compared to a traditional system, especially for small and medium-sized LoRaWAN networks. We also discuss why the proposed solution can be used in environments with a large number of end-devices.

Pré-eclâmpsia em período puerperal: relato de caso / Preeclampsia during postpartum period: a case report

RESUMO: A pré-eclâmpsia, uma complicação frequente da gravidez, é uma das principais causas maternas de morbidade e da mortalidade perinatal. Um grande avanço na classificação da pré-eclâmpsia foi a sua subdivisão em variantes precoces (<34 semanas de gestação) e tardias. Apesar de apresentarem maior prevalência no período gestacional, o aparecimento dessas intercorrências em período pós-parto e puerperal não deve ser negligenciado tendo em vista a sua importância clínica. Este artigo é um relato de caso de pré-eclâmpsia tardia em uma paciente de 37 anos, puérpera, que deu entrada no serviço de emergência hospitalar com quadro de edema agudo de pulmão, dispneia, estado torporoso e cianose periférica. O diagnóstico foi possível através de aferição de pressão arterial sistêmica e dosagem de proteinúria de 24h, tendo sido descartadas outras complicações possíveis após outros exames laboratoriais. O quadro foi estabilizado com uso de nitroprussiato de sódio e uso de pressão positiva contínua nas vias aéreas (do inglês: continuous positive airway pressure­CPAP) para correção de cianose. Logo depois do diagnóstico de pré-eclâmpsia, foi adicionado à prescrição o sulfato de magnésio para profilaxia de eclâmpsia. Após sete dias de internação sem demais intercorrências, a paciente recebeu alta. (AU)

ABSTRACT: Preeclampsia, a frequent complication of pregnancy, is a leading cause of maternal and perinatal morbidity and mortality. A major advance in the classification of preeclampsia was its subdivision into early- (<34 weeks of gestation) and late-onset variants. Although they present a higher prevalence in the gestational period, the appearance of these intercurrences in the postpartum and puerperal period should not be neglected given their clinical importance. It is described a case of late preeclampsia: a 37-year-old patient, at the postpartum period, who went to emergency service after being dyspneic, torporous, peripheral cyanosis, and with pulmonary edema. The diagnosis was made not only based on the medical signs and patient-reported symptoms, but also after laboratory findings such as 24h proteinuria and blood pressure measure. Other diagnoses, as HELLP Syndrome, were excluded after normal laboratory results. Her clinical condition was made stable after being medicated with sodium nitroprusside and using a continuous positive airway pressure (CPAP) for cyanosis correction. After the preeclampsia diagnosis, at another medical center, it was added to the prescription magnesium sulfate as an eclâmpsia prophylaxis. After the seventh day of admission, without other complications, the patient was discharged from the hospital. (AU)

Patrón facial y espacios primates / Facial pattern and primate spaces

El patrón facial indica la dirección del crecimiento de la cara en sentido vertical u horizontal y este crecimiento se ve incrementado en la etapa de la dentición decidua, por lo que podría influir en la presencia de espacios primates. Además, el patrón de crecimiento que se manifiesta en las primeras etapas de vida se mantiene a lo largo de esta, que sumado a la presencia o no de espacios primates en la dentición decidua, nos ayudaría a predecir futuros apiñamientos en el sector anterior de la dentición permanente. La presente revisión de literatura nació a partir de la inquietud sobre la posible relación que existe entre el patrón facial y los espacios primates. No se encontraron estudios que relacionen ambas variables, sin embargo, el patrón facial en niños, así como las características principales de la dentición decidua ha sido ampliamente estudiados a nivel internacional y nacional. (AU)

Sensor data security level estimation scheme for wireless sensor networks.

Due to their increasing dissemination, wireless sensor networks (WSNs) have become the target of more and more sophisticated attacks, even capable of circumventing both attack detection and prevention mechanisms. This may cause WSN users, who totally trust these security mechanisms, to think that a sensor reading is secure, even when an adversary has corrupted it. For that reason, a scheme capable of estimating the security level (SL) that these mechanisms provide to sensor data is needed, so that users can be aware of the actual security state of this data and can make better decisions on its use. However, existing security estimation schemes proposed for WSNs fully ignore detection mechanisms and analyze solely the security provided by prevention mechanisms. In this context, this work presents the sensor data security estimator (SDSE), a new comprehensive security estimation scheme for WSNs. SDSE is designed for estimating the sensor data security level based on security metrics that analyze both attack prevention and detection mechanisms. In order to validate our proposed scheme, we have carried out extensive simulations that show the high accuracy of SDSE estimates.

Sequence analysis of mutations and translocations across breast cancer subtypes.

Breast carcinoma is the leading cause of cancer-related mortality in women worldwide, with an estimated 1.38 million new cases and 458,000 deaths in 2008 alone. This malignancy represents a heterogeneous group of tumours with characteristic molecular features, prognosis and responses to available therapy. Recurrent somatic alterations in breast cancer have been described, including mutations and copy number alterations, notably ERBB2 amplifications, the first successful therapy target defined by a genomic aberration. Previous DNA sequencing studies of breast cancer genomes have revealed additional candidate mutations and gene rearrangements. Here we report the whole-exome sequences of DNA from 103 human breast cancers of diverse subtypes from patients in Mexico and Vietnam compared to matched-normal DNA, together with whole-genome sequences of 22 breast cancer/normal pairs. Beyond confirming recurrent somatic mutations in PIK3CA, TP53, AKT1, GATA3 and MAP3K1, we discovered recurrent mutations in the CBFB transcription factor gene and deletions of its partner RUNX1. Furthermore, we have identified a recurrent MAGI3-AKT3 fusion enriched in triple-negative breast cancer lacking oestrogen and progesterone receptors and ERBB2 expression. The MAGI3-AKT3 fusion leads to constitutive activation of AKT kinase, which is abolished by treatment with an ATP-competitive AKT small-molecule inhibitor.

Implementation of pseudopotential in the G3 theory for molecules containing first-, second-, and non-transition third-row atoms.

Compact effective pseudopotential (CEP) is adapted in the G3 theory providing a theoretical alternative referred to as G3CEP for calculations involving the first-, second-, and non-transition third-row elements. These modifications tried to preserve as much as possible the original characteristics of G3. G3CEP was used in the study of 247 enthalpies of formation, 22 atomization energies, 104 ionization potentials, 63 electron affinities, and 10 proton affinities, resulting in the calculation of 446 species for the first-, second-, and third-row atoms. The final average total absolute deviation was of 1.29 kcal mol(-1) against 1.16 kcal mol(-1) from all-electron G3 for the same calculations. The CPU time has been reduced by 7% to 56%, depending on the size of the molecules and the type of atoms considered.