Transverse Myelitis in the Setting of Enterobius vermicularis (Pinworm) Infection: Case Report.

Myelitis is a rare inflammatory myelopathy, and known associated etiologies only account for a small number of causes. A significant percentage of cases have an unknown etiology and are considered idiopathic. With 64% to 68% of cases fitting into the idiopathic category, helminth infections, and specifically pinworm parainfections, should be considered in cases that would otherwise be classified as idiopathic. This case report outlines a pediatric patient diagnosed with myelitis given her progressive weakness, fussiness, refusal to bear weight as well as magnetic resonance imaging (MRI) demonstrating T2-hyperintense signal and/or T1 gadolinium enhancement, and/or positive cerebrospinal fluid (CSF) inflammatory markers. This patient had a negative evaluation for typical known etiologies for myelitis including no signs of multiple sclerosis and neuromyelitis optica spectrum disorder on brain MRI, oligoclonal banding and aquaporin-4 autoantibodies, and no evidence of bacterial or viral meningitis given normal cell counts and cultures in CSF. She was found to have a pinworm infection, suggesting a parasitic parainfectious etiology of her myelitis. This case outlines the first case noting the correlation between myelitis and pinworm infection in a pediatric patient.

Admissions for Bronchiolitis at Children's Hospitals Before and During the COVID-19 Pandemic.

Importance: The COVID-19 pandemic has been associated with a transient decrease in bronchiolitis hospitalizations compared with prepandemic patterns, but current effects remain unknown. Objective: To analyze changes in patterns of bronchiolitis admissions at US children's hospitals during the 2020-2023 bronchiolitis seasons compared with the 2010-2019 seasons. Design, Setting, and Participants: This retrospective cross-sectional study used data from 41 US children's hospitals in the Pediatric Health Information System database. Bronchiolitis has winter-predominant seasonality, so hospitalizations were grouped according to bronchiolitis season (from July through June). This study included all patients aged younger than 2 years admitted with a diagnosis of bronchiolitis between July 1, 2010, and June 30, 2023. Bronchiolitis seasons from July through June between 2010-2011 and 2019-2020 were classified as the prepandemic era, and seasons between 2020-2021 and 2022-2023 were classified as the pandemic era. Data analysis was performed from July 1, 2010, through June 30, 2023. Exposures: Admission date. Main Outcomes and Measures: The primary outcome was number of hospitalizations for bronchiolitis by season and month. Monthly admission counts from the prepandemic era were transformed into time series and used to train seasonal ensemble forecasting models. Forecasts were compared to monthly admissions during the pandemic era. Results: In this study, there were 400 801 bronchiolitis admissions among 349 609 patients between July 1, 2010, and June 30, 2023. The median patient age was 6 (IQR, 2-12) months; 58.7% were boys and 43.7% were White. Hospitalizations increased gradually during the prepandemic era (median, 29 309 [IQR, 26 196-34 157]), decreased 69.2% (n = 9030) in the 2020-2021 season, and increased 75.3% (n = 51 397) in the 2022-2023 season. Patients in the pandemic era were older than those in the prepandemic era (median, 7 [IQR, 3-14] vs 6 [2-12] months; P < .001). Intensive care unit (ICU) admissions increased from 32.2% (96 245 of 298 535) in the prepandemic era to 36.7% (37 516 of 102 266) in the pandemic era (P < .001). The seasonality of bronchiolitis admissions changed during the pandemic era. Admissions peaked in August 2021 (actual 5036 vs 943 [95% CI, 0-2491] forecasted) and November 2022 (actual 10 120 vs 5268 [95% CI, 3425-7419] forecasted). These findings were unchanged in sensitivity analyses excluding children with complex chronic conditions and excluding repeat admissions. In a sensitivity analysis including all viral lower respiratory tract infections in children aged younger than 5 years, there were 66 767 admissions in 2022-2023 vs 35 623 (31 301-41 002) in the prepandemic era, with the largest increase in children aged 24 to 59 months. Conclusions and Relevance: The findings of this cross-sectional study suggest that bronchiolitis hospitalizations decreased transiently and then increased markedly during the COVID-19 pandemic era. Patients admitted during the pandemic era were older and were more likely to be admitted to an ICU. These findings suggest that bronchiolitis seasonality has not yet returned to prepandemic patterns, and US hospitals should prepare for the possibility of atypical timing again in 2023.

Delayed Onset of Pediatric Morel-Lavallée Lesion: A Case Report.

Introduction: A Morel-Lavallée lesion (MLL) is a closed degloving injury secondary to shearing forces. MLL is a rare, easily overlooked diagnosis, especially in those without recent trauma or fracture. Patients will present with ecchymosis, edema, fluctuance, and skin hypermobility or tightness. We present a case of pediatric MLL that was initially challenging to diagnose as the inciting trauma was 2 months before her diagnosis. Case Report: A 14-year-old girl presented with 5 days of left leg bruising, swelling, and pain. Two months prior, she collided with another softball player's cleat and developed a hairline fracture. Magnetic resonance imaging of the left lower extremity (LLE) showed a closed, soft-tissue degloving injury, and she was diagnosed with a MLL. Throughout her admission, she had improvement in her bruising but continued to have pain with ambulation that was somewhat alleviated with the use of a compression stocking. Pediatric Orthopedic Surgery and Interventional Radiology were consulted, and a conservative approach was recommended with 3 months of LLE compression. Conclusion: MLL typically occurs in patients in their 30-40s and rarely occurs in children. Identifying MLL in children is essential as children are more susceptible to shock and multi-organ damage from blunt trauma than adults. They are also more vulnerable to fractures and deep organ injuries. In the setting of MLL, children can quickly develop hypovolemic shock due to lower blood volumes and necrosis secondary to mass effect in the dead space. MLL should be included on the differential for children with trauma or a history of a shearing injury.

Pediatric Collagenous Gastroenteritis and Colitis Presenting as Protein-Losing Enteropathy.

There is a lack of literature on pediatric collagenous colitis. This is a report of a child with collagenous gastroenteritis and colitis who presented with chronic, nonbloody diarrhea and lower extremity edema secondary to protein-losing enteropathy. Collagenous colitis is rare in children; collagenous gastroenteritis and colitis are even less documented; and this diagnosis does not typically present with protein-losing enteropathy. The pediatric patient in this report had a presentation of a rare disease. Her disease self-resolved, and she has remained asymptomatic without pharmacologic intervention. This illness should be considered in a child presenting with this constellation of symptoms.