A Randomized Clinical Trial to Evaluate the Efficacy of an Oral Probiotic in Acne Vulgaris.

The relevance of the gut microbiota in some skin inflammatory diseases, including acne vulgaris, has been emphasized. Probiotics could play a role in the modulation of the microbiota, improving the clinical course of this disease. A 12-week randomized, double-blind, placebo-controlled, clinical trial with patients aged 12 to 30 years with acne vulgaris was conducted. The study product was a capsule composed of the probiotic Lacticaseibacillus rhamnosus (CECT 30031) and the cyanobacterium Arthrospira platensis (BEA_IDA_0074B). Patients with improvement in the Acne Global Severity Scale were 10/34 (29.41%) in the placebo group compared with 20/40 (50%) in the probiotic group (p = 0.03). A significant reduction (p = 0.03) in the number of non-inflammatory acne lesions was observed in the probiotic group (-18.60 [-24.38 to -12.82]) vs the placebo group (-10.54 [-17.43 to -3.66]). Regarding the number of total  lesions, a reduction almost reaching statistical significance (p = 0.06) was observed in the probiotic group (-27.94 [-36.35 to -19.53]) compared with the placebo group (-18.31 [-28.21 to -8.41]). In addition, patients with improvement attending the Global Acne Grading System were 7/34 (20.58%) in the placebo group vs 17/40 (42.50%) in the probiotic group (p = 0.02). The number of adverse events was similar in both groups. The probiotic used in this study was effective and well tolerated, and it should be considered for acne vulgaris patients.

Análisis de aspectos laborales y formativos de los especialistas egresados tras 20 años de experiencia docente (1993-2012) en el Departamento de Salud del Hospital Universitario San Juan de Alicante / Analysis of working and teaching status of medical specialists trained in the Alicante-San Juan Medical Department, after 20 years of experience (1993-2012)

INTRODUCCIÓN. La información sobre la situación laboral de los especialistas MIR tras su período formativo debería ser un requisito indispensable para una adecuada planificación de la oferta en formación especializada. De igual forma, sería conveniente disponer de la opinión de los egresados sobre su período formativo para identificar áreas de mejora. El objetivo de este estudio es el análisis de ambos aspectos entre los especialistas formados en el Hospital Universitario San Juan de Alicante y su Departamento de Salud tras 20 años de experiencia docente (1993-2012). SUJETOS Y MÉTODOS: Entre junio de 2013 y abril de 2014 se llevó a cabo un estudio observacional descriptivo mediante encuesta de opinión que incluía preguntas en dos bloques, laboral y formativo, y que se distribuyó entre los MIR formados en el centro en el período 1993-2012. El número de especialidades analizadas fue 16. RESULTADOS: De los 272 especialistas, respondió a la encuesta un 71%, el 93% en las especialidades hospitalarias. Al responderla, ninguno se encontraba en paro. Un 74% tenía trabajo estable y el 75% trabajaba en la provincia de Alicante. En nueve de las 16 especialidades, más del 80% de los especialistas encontró trabajo en el mes tras finalizar el período MIR. Casi el 70% volvería a elegir la plaza en la que se formó. El 93% de los encuestados manifestó sentirse solvente al realizar su trabajo. CONCLUSIONES: Aunque un 7% de los especialistas tardó más de seis meses en encontrar trabajo y en dos especialidades (medicina nuclear y medicina interna) el trabajo inestable superó al estable, la situación laboral y formativa de los MIR egresados en nuestro departamento hasta el año 2012 puede considerarse satisfactoria, con pleno empleo y niveles altos de percepción de solvencia en su trabajo como especialistas

INTRODUCTION: Information about medical employment after the specialist's training period should be an essential requirement for planning of future teaching needs. In the same way, it would be convenient to consider the trainee's opinion about their training period in order to identify different areas to be improved. The aim of this study was to analyse the opinion of doctors trained in the University Hospital of San Juan de Alicante about their working conditions and teaching program. SUBJECTS AND METHODS: In the period between June/2013 and April/2014, an observational descriptive study through a questionnaire survey was performed, including two groups of questions that were answered by the specialists trained in the Health Department of Alicante-San Juan after 20 years (1993-2012). Sixteen medical specialities were analysed. RESULTS: The questionnaire was answered by 71% of 272 trained specialists, 93% of hospital specialties (not including primary care). When the questionnaire was answered, any of the specialists was on unemployment. Seventy four percent had a stable job, and 75% were working in the province of Alicante. In 9 of the 16 specialties, more than 80% of the specialists were already working in the first month after finishing their training period. Almost 70% would choose the same specialty again. Ninety three percent expressed to feel solvent in their job as a specialist. CONCLUSIONS: Seven percent of the specialists remained in unemployment more than 6 months and, in nuclear and internal medicine, the number of unstable jobs exceeded the stable jobs. However, up to 2012, the working and educational situation of medical specialists trained in the University Hospital of San Juan de Alicante can be considered satisfactory, with full employment and a very good self-perception of solvency