A machine learning and deep learning-based integrated multi-omics technique for leukemia prediction.

In recent years, scientific data on cancer has expanded, providing potential for a better understanding of malignancies and improved tailored care. Advances in Artificial Intelligence (AI) processing power and algorithmic development position Machine Learning (ML) and Deep Learning (DL) as crucial players in predicting Leukemia, a blood cancer, using integrated multi-omics technology. However, realizing these goals demands novel approaches to harness this data deluge. This study introduces a novel Leukemia diagnosis approach, analyzing multi-omics data for accuracy using ML and DL algorithms. ML techniques, including Random Forest (RF), Naive Bayes (NB), Decision Tree (DT), Logistic Regression (LR), Gradient Boosting (GB), and DL methods such as Recurrent Neural Networks (RNN) and Feedforward Neural Networks (FNN) are compared. GB achieved 97 % accuracy in ML, while RNN outperformed by achieving 98 % accuracy in DL. This approach filters unclassified data effectively, demonstrating the significance of DL for leukemia prediction. The testing validation was based on 17 different features such as patient age, sex, mutation type, treatment methods, chromosomes, and others. Our study compares ML and DL techniques and chooses the best technique that gives optimum results. The study emphasizes the implications of high-throughput technology in healthcare, offering improved patient care.

Artificial Intelligence-Based Secured Power Grid Protocol for Smart City.

Due to the modern power system's rapid development, more scattered smart grid components are securely linked into the power system by encircling a wide electrical power network with the underpinning communication system. By enabling a wide range of applications, such as distributed energy management, system state forecasting, and cyberattack security, these components generate vast amounts of data that automate and improve the efficiency of the smart grid. Due to traditional computer technologies' inability to handle the massive amount of data that smart grid systems generate, AI-based alternatives have received a lot of interest. Long Short-Term Memory (LSTM) and recurrent Neural Networks (RNN) will be specifically developed in this study to address this issue by incorporating the adaptively time-developing energy system's attributes to enhance the model of the dynamic properties of contemporary Smart Grid (SG) that are impacted by Revised Encoding Scheme (RES) or system reconfiguration to differentiate LSTM changes & real-time threats. More specifically, we provide a federated instructional strategy for consumer sharing of power data to Power Grid (PG) that is supported by edge clouds, protects consumer privacy, and is communication-efficient. They then design two optimization problems for Energy Data Owners (EDO) and energy service operations, as well as a local information assessment method in Federated Learning (FL) by taking non-independent and identically distributed (IID) effects into consideration. The test results revealed that LSTM had a longer training duration, four hidden levels, and higher training loss than other models. The provided method works incredibly well in several situations to identify FDIA. The suggested approach may successfully induce EDOs to employ high-quality local models, increase the payout of the ESP, and decrease task latencies, according to extensive simulations, which are the last points. According to the verification results, every assault sample could be effectively recognized utilizing the current detection methods and the LSTM RNN-based structure created by Smart.

An Intelligent Attention-Based Transfer Learning Model for Accurate Differentiation of Bone Marrow Stains to Diagnose Hematological Disorder.

Bone marrow (BM) is an essential part of the hematopoietic system, which generates all of the body's blood cells and maintains the body's overall health and immune system. The classification of bone marrow cells is pivotal in both clinical and research settings because many hematological diseases, such as leukemia, myelodysplastic syndromes, and anemias, are diagnosed based on specific abnormalities in the number, type, or morphology of bone marrow cells. There is a requirement for developing a robust deep-learning algorithm to diagnose bone marrow cells to keep a close check on them. This study proposes a framework for categorizing bone marrow cells into seven classes. In the proposed framework, five transfer learning models-DenseNet121, EfficientNetB5, ResNet50, Xception, and MobileNetV2-are implemented into the bone marrow dataset to classify them into seven classes. The best-performing DenseNet121 model was fine-tuned by adding one batch-normalization layer, one dropout layer, and two dense layers. The proposed fine-tuned DenseNet121 model was optimized using several optimizers, such as AdaGrad, AdaDelta, Adamax, RMSprop, and SGD, along with different batch sizes of 16, 32, 64, and 128. The fine-tuned DenseNet121 model was integrated with an attention mechanism to improve its performance by allowing the model to focus on the most relevant features or regions of the image, which can be particularly beneficial in medical imaging, where certain regions might have critical diagnostic information. The proposed fine-tuned and integrated DenseNet121 achieved the highest accuracy, with a training success rate of 99.97% and a testing success rate of 97.01%. The key hyperparameters, such as batch size, number of epochs, and different optimizers, were all considered for optimizing these pre-trained models to select the best model. This study will help in medical research to effectively classify the BM cells to prevent diseases like leukemia.

Enhancing Breast Cancer Detection and Classification Using Advanced Multi-Model Features and Ensemble Machine Learning Techniques.

Breast cancer (BC) is the most common cancer among women, making it essential to have an accurate and dependable system for diagnosing benign or malignant tumors. It is essential to detect this cancer early in order to inform subsequent treatments. Currently, fine needle aspiration (FNA) cytology and machine learning (ML) models can be used to detect and diagnose this cancer more accurately. Consequently, an effective and dependable approach needs to be developed to enhance the clinical capacity to diagnose this illness. This study aims to detect and divide BC into two categories using the Wisconsin Diagnostic Breast Cancer (WDBC) benchmark feature set and to select the fewest features to attain the highest accuracy. To this end, this study explores automated BC prediction using multi-model features and ensemble machine learning (EML) techniques. To achieve this, we propose an advanced ensemble technique, which incorporates voting, bagging, stacking, and boosting as combination techniques for the classifier in the proposed EML methods to distinguish benign breast tumors from malignant cancers. In the feature extraction process, we suggest a recursive feature elimination technique to find the most important features of the WDBC that are pertinent to BC detection and classification. Furthermore, we conducted cross-validation experiments, and the comparative results demonstrated that our method can effectively enhance classification performance and attain the highest value in six evaluation metrics, including precision, sensitivity, area under the curve (AUC), specificity, accuracy, and F1-score. Overall, the stacking model achieved the best average accuracy, at 99.89%, and its sensitivity, specificity, F1-score, precision, and AUC/ROC were 1.00%, 0.999%, 1.00%, 1.00%, and 1.00%, respectively, thus generating excellent results. The findings of this study can be used to establish a reliable clinical detection system, enabling experts to make more precise and operative decisions in the future. Additionally, the proposed technology might be used to detect a variety of cancers.

Detection of offensive terms in resource-poor language using machine learning algorithms.

The use of offensive terms in user-generated content on different social media platforms is one of the major concerns for these platforms. The offensive terms have a negative impact on individuals, which may lead towards the degradation of societal and civilized manners. The immense amount of content generated at a higher speed makes it humanly impossible to categorise and detect offensive terms. Besides, it is an open challenge for natural language processing (NLP) to detect such terminologies automatically. Substantial efforts are made for high-resource languages such as English. However, it becomes more challenging when dealing with resource-poor languages such as Urdu. Because of the lack of standard datasets and pre-processing tools for automatic offensive terms detection. This paper introduces a combinatorial pre-processing approach in developing a classification model for cross-platform (Twitter and YouTube) use. The approach uses datasets from two different platforms (Twitter and YouTube) the training and testing the model, which is trained to apply decision tree, random forest and naive Bayes algorithms. The proposed combinatorial pre-processing approach is applied to check how machine learning models behave with different combinations of standard pre-processing techniques for low-resource language in the cross-platform setting. The experimental results represent the effectiveness of the machine learning model over different subsets of traditional pre-processing approaches in building a classification model for automatic offensive terms detection for a low resource language, i.e., Urdu, in the cross-platform scenario. In the experiments, when dataset D1 is used for training and D2 is applied for testing, the pre-processing approach named Stopword removal produced better results with an accuracy of 83.27%. Whilst, in this case, when dataset D2 is used for training and D1 is applied for testing, stopword removal and punctuation removal were observed as a better preprocessing approach with an accuracy of 74.54%. The combinatorial approach proposed in this paper outperformed the benchmark for the considered datasets using classical as well as ensemble machine learning with an accuracy of 82.9% and 97.2% for dataset D1 and D2, respectively.

EfficientNetB0 cum FPN Based Semantic Segmentation of Gastrointestinal Tract Organs in MRI Scans.

The segmentation of gastrointestinal (GI) organs is crucial in radiation therapy for treating GI cancer. It allows for developing a targeted radiation therapy plan while minimizing radiation exposure to healthy tissue, improving treatment success, and decreasing side effects. Medical diagnostics in GI tract organ segmentation is essential for accurate disease detection, precise differential diagnosis, optimal treatment planning, and efficient disease monitoring. This research presents a hybrid encoder-decoder-based model for segmenting healthy organs in the GI tract in biomedical images of cancer patients, which might help radiation oncologists treat cancer more quickly. Here, EfficientNet B0 is used as a bottom-up encoder architecture for downsampling to capture contextual information by extracting meaningful and discriminative features from input images. The performance of the EfficientNet B0 encoder is compared with that of three encoders: ResNet 50, MobileNet V2, and Timm Gernet. The Feature Pyramid Network (FPN) is a top-down decoder architecture used for upsampling to recover spatial information. The performance of the FPN decoder was compared with that of three decoders: PAN, Linknet, and MAnet. This paper proposes a segmentation model named as the Feature Pyramid Network (FPN), with EfficientNet B0 as the encoder. Furthermore, the proposed hybrid model is analyzed using Adam, Adadelta, SGD, and RMSprop optimizers. Four performance criteria are used to assess the models: the Jaccard and Dice coefficients, model loss, and processing time. The proposed model can achieve Dice coefficient and Jaccard index values of 0.8975 and 0.8832, respectively. The proposed method can assist radiation oncologists in precisely targeting areas hosting cancer cells in the gastrointestinal tract, allowing for more efficient and timely cancer treatment.

Achieving model explainability for intrusion detection in VANETs with LIME.

Vehicular ad hoc networks (VANETs) are intelligent transport subsystems; vehicles can communicate through a wireless medium in this system. There are many applications of VANETs such as traffic safety and preventing the accident of vehicles. Many attacks affect VANETs communication such as denial of service (DoS) and distributed denial of service (DDoS). In the past few years the number of DoS (denial of service) attacks are increasing, so network security and protection of the communication systems are challenging topics; intrusion detection systems need to be improved to identify these attacks effectively and efficiently. Many researchers are currently interested in enhancing the security of VANETs. Based on intrusion detection systems (IDS), machine learning (ML) techniques were employed to develop high-security capabilities. A massive dataset containing application layer network traffic is deployed for this purpose. Interpretability technique Local interpretable model-agnostic explanations (LIME) technique for better interpretation model functionality and accuracy. Experimental results demonstrate that utilizing a random forest (RF) classifier achieves 100% accuracy, demonstrating its capability to identify intrusion-based threats in a VANET setting. In addition, LIME is applied to the RF machine learning model to explain and interpret the classification, and the performance of machine learning models is evaluated in terms of accuracy, recall, and F1 score.

Detection of Pneumonia from Chest X-ray Images Utilizing MobileNet Model.

Pneumonia has been directly responsible for a huge number of deaths all across the globe. Pneumonia shares visual features with other respiratory diseases, such as tuberculosis, which can make it difficult to distinguish between them. Moreover, there is significant variability in the way chest X-ray images are acquired and processed, which can impact the quality and consistency of the images. This can make it challenging to develop robust algorithms that can accurately identify pneumonia in all types of images. Hence, there is a need to develop robust, data-driven algorithms that are trained on large, high-quality datasets and validated using a range of imaging techniques and expert radiological analysis. In this research, a deep-learning-based model is demonstrated for differentiating between normal and severe cases of pneumonia. This complete proposed system has a total of eight pre-trained models, namely, ResNet50, ResNet152V2, DenseNet121, DenseNet201, Xception, VGG16, EfficientNet, and MobileNet. These eight pre-trained models were simulated on two datasets having 5856 images and 112,120 images of chest X-rays. The best accuracy is obtained on the MobileNet model with values of 94.23% and 93.75% on two different datasets. Key hyperparameters including batch sizes, number of epochs, and different optimizers have all been considered during comparative interpretation of these models to determine the most appropriate model.

ResRandSVM: Hybrid Approach for Acute Lymphocytic Leukemia Classification in Blood Smear Images.

Acute Lymphocytic Leukemia is a type of cancer that occurs when abnormal white blood cells are produced in the bone marrow which do not function properly, crowding out healthy cells and weakening the immunity of the body and thus its ability to resist infections. It spreads quickly in children's bodies, and if not treated promptly it may lead to death. The manual detection of this disease is a tedious and slow task. Machine learning and deep learning techniques are faster than manual detection and more accurate. In this paper, a deep feature selection-based approach ResRandSVM is proposed for the detection of Acute Lymphocytic Leukemia in blood smear images. The proposed approach uses seven deep-learning models: ResNet152, VGG16, DenseNet121, MobileNetV2, InceptionV3, EfficientNetB0 and ResNet50 for deep feature extraction from blood smear images. After that, three feature selection methods are used to extract valuable and important features: analysis of variance (ANOVA), principal component analysis (PCA), and Random Forest. Then the selected feature map is fed to four different classifiers, Adaboost, Support Vector Machine, Artificial Neural Network and Naïve Bayes models, to classify the images into leukemia and normal images. The model performs best with a combination of ResNet50 as a feature extractor, Random Forest as feature selection and Support Vector Machine as a classifier with an accuracy of 0.900, precision of 0.902, recall of 0.957 and F1-score of 0.929.

A Convolutional Neural Network Architecture for Segmentation of Lung Diseases Using Chest X-ray Images.

The segmentation of lungs from medical images is a critical step in the diagnosis and treatment of lung diseases. Deep learning techniques have shown great promise in automating this task, eliminating the need for manual annotation by radiologists. In this research, a convolution neural network architecture is proposed for lung segmentation using chest X-ray images. In the proposed model, concatenate block is embedded to learn a series of filters or features used to extract meaningful information from the image. Moreover, a transpose layer is employed in the concatenate block to improve the spatial resolution of feature maps generated by a prior convolutional layer. The proposed model is trained using k-fold validation as it is a powerful and flexible tool for evaluating the performance of deep learning models. The proposed model is evaluated on five different subsets of the data by taking the value of k as 5 to obtain the optimized model to obtain more accurate results. The performance of the proposed model is analyzed for different hyper-parameters such as the batch size as 32, optimizer as Adam and 40 epochs. The dataset used for the segmentation of disease is taken from the Kaggle repository. The various performance parameters such as accuracy, IoU, and dice coefficient are calculated, and the values obtained are 0.97, 0.93, and 0.96, respectively.