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2.
Rev Sci Instrum ; 88(3): 035101, 2017 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-28372382

RESUMEN

This paper presents an innovative forced oscillations dynamic tribometer, the CHRONOS tribometer, with a lubricated ball-on-flat contact configuration fitted out with an in situ optical visualization system and a triggered high-speed camera. The CHRONOS tribometer generates controlled oscillating kinematics by means of a shaker with a range of strokes from 5 µm to 2.5 mm and an oscillation frequency which can be adjusted from 5 Hz to 250 Hz. Displacement and velocity are measured using a vibrometer. The ball-on-flat mean contact pressure is set between 200 MPa and 600 MPa. During motion, the instantaneous normal and friction forces and the interfacial film thickness distribution (in the nanometer scale) are simultaneously measured. In addition to this instantaneous approach, a more macroscopic approach is developed in terms of moving averages of friction and velocity. Another parameter, the friction-velocity tilt angle, is also introduced. This last parameter may give information on the friction-velocity dependence. Eventually, the experiments performed on the CHRONOS device lead to the representation of synchronized temporal signals of displacement/velocity, friction, and lubricant central film thickness. This superimposition of key parameters reveals time effects introduced by the periodical fluid squeeze and flow in the contact.

3.
Clin Microbiol Infect ; 22(8): 735.e1-9, 2016 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-27237545

RESUMEN

In order to assess the level of occupational exposure to the main pathogens transmitted by the Ixodes ricinus tick, a seroprevalence study was performed on serum samples collected in 2003 from 2975 forestry workers of northeastern France. The global seroprevalence estimated for the seven pathogens studied was 14.1% (419/2975) for Borrelia burgdorferi sl, 5.7% (164/2908) for Francisella tularensis, 2.3% (68/2941) for tick-borne encephalitis virus, 1.7% (50/2908) for Anaplasma phagocytophilum and 1.7% (48/2908) for Bartonella henselae. The seroprevalences of Babesia divergens and Babesia microti studied in a subgroup of participants seropositive for at least one of these latter pathogens were 0.1% (1/810) and 2.5% (20/810), respectively. Borrelia burgdorferi sl seroprevalence was significantly higher in Alsace and Lorraine and F. tularensis seroprevalence was significantly higher in Champagne-Ardenne and Franche-Comté. The results of this survey also suggest low rates of transmission of Bartonella henselae and F. tularensis by ticks and a different west/east distribution of Babesia species in France. The frequency and potential severity of these diseases justify continued promotion of methods of prevention of I. ricinus bites.


Asunto(s)
Agricultores , Bosques , Ixodes/microbiología , Enfermedades por Picaduras de Garrapatas/epidemiología , Enfermedades por Picaduras de Garrapatas/microbiología , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Animales , Estudios Transversales , Femenino , Francia/epidemiología , Geografía , Humanos , Masculino , Persona de Mediana Edad , Exposición Profesional , Oportunidad Relativa , Vigilancia de la Población , Estudios Seroepidemiológicos , Enfermedades por Picaduras de Garrapatas/transmisión , Adulto Joven
4.
Med Mal Infect ; 38(10): 533-42, 2008 Oct.
Artículo en Francés | MEDLINE | ID: mdl-18722066

RESUMEN

OBJECTIVE: The aim of this article was to assess the seroprevalence of Lyme Borreliosis and tick-borne encephalitis (TBE) among occupationally exposed forest workers. METHODS: Workers exposed to tick bites in Eastern France were interviewed by occupational health physicians of the mutualité sociale agricole (MSA) on their sociodemographic features, their occupational activity, their last tick bite, their clinical history, and their means of prevention. Blood sampling was carried out for antibody detection. RESULTS: Among the 2975 subjects included in the study, the observed seroprevalence was 14.1% for Lyme borreliosis and 3.4% for TBE. Age, occupational activity, and place of residence significantly influenced the serological status of Lyme borreliosis. The seroprevalence was significantly higher among woodcutters (17.5%) than among other occupational categories (p<.001). Seroprevalence in Alsace (26.9%) and Lorraine (16.5%) were significantly higher than in other regions (p<0.001 and p<0.01, respectively). The seroprevalence of TBE was significantly higher in Alsace (5.5%; p<0.001). The rates of seroprevalence for both infections varied according to forest areas. The multifactorial analysis of prevention practices revealed three types of behaviors as far as protection was concerned: "rigorous", "partial", or "insufficient". CONCLUSION: These results do not change the present French indications for use of TBE vaccine. They highlight the importance of information on these diseases and the need for further studies on microbial ecology and risk-factors identification.


Asunto(s)
Encefalitis Transmitida por Garrapatas/epidemiología , Agricultura Forestal , Enfermedad de Lyme/epidemiología , Enfermedades Profesionales/epidemiología , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Animales , Anticuerpos Antibacterianos/sangre , Anticuerpos Antivirales/sangre , Vectores Arácnidos/microbiología , Vectores Arácnidos/virología , Mordeduras y Picaduras/epidemiología , Mordeduras y Picaduras/microbiología , Mordeduras y Picaduras/virología , Borrelia burgdorferi/inmunología , Virus de la Encefalitis Transmitidos por Garrapatas/inmunología , Encefalitis Transmitida por Garrapatas/prevención & control , Encefalitis Transmitida por Garrapatas/transmisión , Femenino , Francia/epidemiología , Humanos , Enfermedad de Lyme/prevención & control , Enfermedad de Lyme/transmisión , Masculino , Persona de Mediana Edad , Enfermedades Profesionales/prevención & control , Estudios Seroepidemiológicos , Garrapatas/microbiología , Garrapatas/virología , Adulto Joven
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