Extracts from the Leaf of Couroupita guianensis (Aubl.): Phytochemical, Toxicological Analysis and Evaluation of Antioxidant and Antimicrobial Activities against Oral Microorganisms.

The study of phytotherapy in dentistry holds great relevance because of the scarcity of research conducted on the treatment of oral pathologies, specifically, caries and periodontal disease. Therefore, this research aimed to analyze the chemical composition of extracts from Couroupita guianensis Aubl. leaves, evaluate their toxicity, and assess their antioxidant and antimicrobial properties against Staphylococcus aureus, Streptococcus mutans, and Candida albicans. Three extracts were prepared using assisted ultrasound and the Soxhlet apparatus, namely, Crude Ultrasound Extract (CUE), Crude Soxhlet Extract (CSE), and the Ethanol Soxhlet Extract (ESE). Flavonoids, tannins, and saponins were detected in the chemical analysis, while LC-DAD analysis revealed the presence of caffeic acid, sinapic acid, rutin, quercetin, luteolin, kaempferol, and apigenin in all extracts. GC-MS analysis identified stigmasterol and ß-sitosterol in the CUE and CSE. The ESE showed higher antioxidant activity (2.98 ± 0.96 and 4.93 ± 0.90) determined by the DPPH• and ABTS•+ methods, respectively. In the toxicity evaluation, the CUE at 50 µg/mL and the ESE at 50 µg/mL stimulated the growth of Allium cepa roots, while all extracts inhibited root growth at 750 µg/mL. None of the extracts exhibited toxicity against Artemia salina. Antibacterial activity was observed in all extracts, particularly against the microorganisms S. aureus and S. mutans. However, no antifungal activity against C. albicans was detected. These results suggest that extracts of C. guianensis have therapeutic potential for controlling microorganisms in the oral microbiota.

Cabelo em neurocirurgia: é necessária a tricotomia? / Hair in neurosurgical: is necessary the hair removal?

Este trabalho relata a nossa experiência que conclui ser desnecessária a tricotomia do couro cabeludo no preparo pré-operatório das craniotomias. No Hospital Nove de Julho, desde o final do ano de 1992, foi abolida a tricotomia do couro cabeludo como rotina nos procedimentos neurocirúrgicos

Enfermeira (o) em neurocirurgia / Nurse in neurosurgery

Relatamos nesse trabalho nossa experiência de enfermeiras em neurocirurgia. Enfocamos a sala cirúrgica dentro do Centro Cirúrgico do Hospsital Nove de Julho, o papel da enfermeira em relaçäo as visitas pré e pós-operatórias, o nosso contato com a Comissäo de Controle de Infecçäo Hospitalar (CCIH), a atuaçäo no Centro Cirúrgico, com nossa carga horária, e nossas atividades em relaçäo ao preparo da sala; cuidados após a chegada do paciente no que se refere a recepçäo, seu conforto, segurança, seu posicionamento; o início da cirurgia com suas diversas etapas; término da cirurgia onde dispensamos cuidados ao paciente; a após a saída do paciente procuramos organizar a sal, dar cuidados a materiais especiais; e além de tudo nosso contato direto com a supervisäo do Centro Cirúrgico. Chegamos ao fim do trabalho concluindo o que nos resultou dessa experiência