1.
Anal Chem
; 60(20): 2249-53, 1988 Oct 15.
Artículo
en Inglés
| MEDLINE
| ID: mdl-3239797
2.
Chem Res Toxicol
; 1(2): 123-7, 1988.
Artículo
en Inglés
| MEDLINE
| ID: mdl-2979719
RESUMEN
Organophosphorus compounds have been shown to exhibit toxic behavior as insecticides, pesticides, and mammalicides. Soman and 21 related compounds were studied for possible structure-activity relationships. Computer-aided methods were used to generate a linear expression relating the activity (ln [1/LD50], rabbit I.V.) of the compounds to three structure-based descriptors (R = 0.96). Principal components regression and jackknife analysis were performed to assess the stability of the model.
Asunto(s)
Compuestos Organofosforados/química , Gráficos por Computador , Modelos Moleculares , Conformación Molecular , Relación Estructura-Actividad
3.
Anal Chem
; 59(7): 1048-54, 1987 Apr 01.
Artículo
en Inglés
| MEDLINE
| ID: mdl-3592213